Search Results - "Satwani, Prakash"

Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen Receptor Consortium Report by Schultz, Liora M, Baggott, Christina, Prabhu, Snehit, Pacenta, Holly L, Phillips, Christine L, Rossoff, Jenna, Stefanski, Heather E, Talano, Julie-An, Moskop, Amy, Margossian, Steven P, Verneris, Michael R, Myers, Gary Douglas, Karras, Nicole A, Brown, Patrick A, Qayed, Muna, Hermiston, Michelle, Satwani, Prakash, Krupski, Christa, Keating, Amy K, Wilcox, Rachel, Rabik, Cara A, Fabrizio, Vanessa A, Rouce, Rayne H, Chinnabhandar, Vasant, Kunicki, Michael, Barsan, Valentin V, Goksenin, A Yasemin, Li, Yimei, Mavroukakis, Sharon, Egeler, Emily, Curran, Kevin J, Mackall, Crystal L, Laetsch, Theodore W

“…Tisagenlecleucel is a CD19-specific chimeric antigen receptor T-cell therapy, US Food and Drug Administration-approved for children, adolescents, and young…”
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Risk factors for chronic kidney disease following acute kidney injury in pediatric allogeneic hematopoietic cell transplantation by Prasad, Malavika, Jain, Namrata G., Radhakrishnan, Jai, Jin, Zhezhen, Satwani, Prakash

“…Risk factors associated with the progression of acute kidney injury to chronic kidney disease in pediatric allogeneic hematopoietic cell transplantation…”
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Healthcare utilization and financial impact of acute-graft-versus host disease among children undergoing allogeneic hematopoietic cell transplantation by Ricci, Angela, Jin, Zhezhen, Broglie, Larisa, Bhatia, Monica, George, Diane, Garvin, James H., Hall, Matthew, Satwani, Prakash

“…The impact of AGVHD on healthcare utilization and cost is not well described. In this retrospective single center cohort study of 240 pediatric patients, we…”
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Financial impact of post-transplant complications among children undergoing allogeneic hematopoietic cell transplantation by Ricci, Angela, Jin, Zhezhen, Bourgeois, Wallace, Broglie, Larisa, Bhatia, Monica, Davis, Laurie, George, Diane, Garvin, James H., Hall, Matthew, Ruiz, Jenny, Satwani, Prakash

“…Complications following allogeneic hematopoietic cell transplantation (alloHCT) continue to be a significant challenge that often result in significant…”
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Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes by Marsh, Rebecca A., Rao, Kanchan, Satwani, Prakash, Lehmberg, Kai, Müller, Ingo, Li, Dandan, Kim, Mi-Ok, Fischer, Alain, Latour, Sylvain, Sedlacek, Petr, Barlogis, Vincent, Hamamoto, Kazuko, Kanegane, Hirokazu, Milanovich, Sam, Margolis, David A., Dimmock, David, Casper, James, Douglas, Dorothea N., Amrolia, Persis J., Veys, Paul, Kumar, Ashish R., Jordan, Michael B., Bleesing, Jack J., Filipovich, Alexandra H.

“…There have been no studies on patient outcome after allogeneic hematopoietic cell transplantation (HCT) in patients with X-linked inhibitor of apoptosis (XIAP)…”
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A Phase 3, Single-Arm, Prospective Study of Remestemcel-L, Ex Vivo Culture-Expanded Adult Human Mesenchymal Stromal Cells for the Treatment of Pediatric Patients Who Failed to Respond to Steroid Treatment for Acute Graft-versus-Host Disease by Kurtzberg, Joanne, Abdel-Azim, Hisham, Carpenter, Paul, Chaudhury, Sonali, Horn, Biljana, Mahadeo, Kris, Nemecek, Eneida, Neudorf, Steven, Prasad, Vinod, Prockop, Susan, Quigg, Troy, Satwani, Prakash, Cheng, Annie, Burke, Elizabeth, Hayes, Jack, Skerrett, Donna

“…•This is the first mesenchymal stromal cell study in acute graft-versus-host disease (aGVHD) to meet a primary efficacy endpoint.•There are no approved…”
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Case Report: Secondary Hemophagocytic Lymphohistiocytosis With Disseminated Infection in Chronic Granulomatous Disease-A Serious Cause of Mortality by Squire, Jacqueline D, Vazquez, Stephanie N, Chan, Angela, Smith, Michele E, Chellapandian, Deepak, Vose, Laura, Teppa, Beatriz, Hanson, I Celine, Chinn, Ivan K, Forbes-Satter, Lisa, Seeborg, Filiz O, Nicholas, Sarah K, Martinez, Caridad A, Allen, Carl E, Connors, Thomas J, Satwani, Prakash, Shtessel, Maria, Ale, Hanadys, Noroski, Lenora M, Rider, Nicholas L, Milner, Joshua D, Leiding, Jennifer W

“…Chronic granulomatous disease (CGD) is a primary immune deficiency due to defects in phagocyte respiratory burst leading to severe and life-threatening…”
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Juvenile Myelomonocytic Leukemia by Satwani, Prakash, MD, Kahn, Justine, MD, Dvorak, Christopher C., MD

“…Juvenile myelomonocytic leukemia (JMML), a rare myeloid malignancy that occurs in young children, is considered a clonal disease originating in pluripotent…”
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Bacterial bloodstream infections in pediatric allogeneic hematopoietic stem cell recipients before and after implementation of a central line-associated bloodstream infection protocol: A single-center experience by Chang, Alicia K., MD, Foca, Marc D., MD, Jin, Zhezhen, MD, Vasudev, Rahul, MD, Laird, Mary, RN, PNP, Schwartz, Sharon, RN, PNP, Qureshi, Mahvish, MD, Kolb, Michelle, RN, PNP, Levinson, Anya, MD, Bhatia, Monica, MD, Kung, Andrew, MD, PhD, Garvin, James, MD, PhD, George, Diane, MD, Della-Latta, Phyllis, PhD, Whittier, Susan, PhD, Saiman, Lisa, MD, MPH, Satwani, Prakash, MD

“…Highlights • Maintenance of CLABSI prevention strategies. • Significant decrease in S. epidermidis blood stream infection. • Significant decrease in Gram…”
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Study 275: Updated Expanded Access Program for Remestemcel-L in Steroid-Refractory Acute Graft-versus-Host Disease in Children by Kurtzberg, Joanne, Prockop, Susan, Chaudhury, Sonali, Horn, Biljana, Nemecek, Eneida, Prasad, Vinod, Satwani, Prakash, Teira, Pierre, Hayes, Jack, Burke, Elizabeth

“…•There are no approved therapies for acute graft-versus-host disease (aGVHD) in children <12 years.•A total of 241 children with steroid-refractory aGVHD…”
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Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance by Narayan, Gopeshwar, Freddy, Allen J., Xie, Dongxu, Liyanage, Hema, Clark, Lorraine, Kisselev, Sergey, Un Kang, Ji, Nandula, Subhadra V., McGuinn, Catherine, Subramaniyam, Shivakumar, Alobeid, Bachir, Satwani, Prakash, Savage, David, Bhagat, Govind, Murty, Vundavalli V.

“…PCDH10 has been implicated as a tumor suppressor, since epigenetic alterations of this gene have been noted in multiple tumor types. However, to date, studies…”
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Health-related quality of life (HRQoL): The impact of medical and demographic variables upon pediatric recipients of hematopoietic stem cell transplantation by Brice, Lisa, Weiss, Rebecca, Wei, Ying, Satwani, Prakash, Bhatia, Monica, George, Diane, Garvin, James, Morris, Erin, Harrison, Lauren, Cairo, Mitchell S., Sands, Stephen A.

“…Background The trajectory of Heath‐Related Quality of Life (HRQoL) in pediatric recipients who have undergone hematopoietic stem cell transplantation (HSCT),…”
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HSC extrinsic sex-related and intrinsic autoimmune disease–related human B-cell variation is recapitulated in humanized mice by Borsotti, Chiara, Danzl, Nichole M., Nauman, Grace, Hölzl, Markus A., French, Clare, Chavez, Estefania, Khosravi-Maharlooei, Mohsen, Glauzy, Salome, Delmotte, Fabien R., Meffre, Eric, Savage, David G., Campbell, Sean R., Goland, Robin, Greenberg, Ellen, Bi, Jing, Satwani, Prakash, Yang, Suxiao, Bathon, Joan, Winchester, Robert, Sykes, Megan

“…B cells play a major role in antigen presentation and antibody production in the development of autoimmune diseases, and some of these diseases…”
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Clinical and Economic Impact of Cytomegalovirus Infection among Children Undergoing Allogeneic Hematopoietic Cell Transplantation by Rastogi, Sonal, Ricci, Angela, Jin, Zhezhen, Bhatia, Monica, George, Diane, Garvin, James H., Hall, Matthew, Satwani, Prakash

“…•Cytomegalovirus (CMV) infection is associated with longer hospitalization.•CMV infection results in higher cost of allogeneic hematopoietic cell…”
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Mesenchymal stromal cells: Getting ready for clinical primetime by Wobma, Holly, Satwani, Prakash

“…Mesenchymal stromal cells (MSC) are multipotent precursor cells that can be derived from a variety of tissue sources, with a working definition based on…”
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Preliminary Results of the Safety of Immunotherapy with Gemtuzumab Ozogamicin following Reduced Intensity Allogeneic Stem Cell Transplant in Children with CD33+ Acute Myeloid Leukemia by ROMAN, Elizabeth, COONEY, Erin, BRADLEY, Brigid, DEL TORO, Gustavo, GEORGE, Diane, GARVIN, James, VAN DEVEN, Carmella, CAIRO, Mitchell S, HARRISON, Lauren, MILITANO, Olga, WOLOWNIK, Karen, HAWKS, Ria, FOLEY, Sandi, SATWANI, Prakash, UNAL, Elif, BHATIA, Monica

“…Purpose: Myeloablative allogeneic stem cell transplantation (SCT) has been successful in the treatment of childhood acute myeloid leukemia (AML), but may be…”
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Risk Factors and Utility of a Risk-Based Algorithm for Monitoring Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections in Pediatric Recipients after Allogeneic Hematopoietic Cell Transplantation by Rustia, Evelyn, Violago, Leah, Jin, Zhezhen, Foca, Marc D, Kahn, Justine M, Arnold, Staci, Sosna, Jean, Bhatia, Monica, Kung, Andrew L, George, Diane, Garvin, James H, Satwani, Prakash

“…Abstract Infectious complications, particularly viral infections, remain a significant cause of morbidity and mortality after allogeneic hematopoietic cell…”
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Transplantation-Related Mortality, Graft Failure, and Survival after Reduced-Toxicity Conditioning and Allogeneic Hematopoietic Stem Cell Transplantation in 100 Consecutive Pediatric Recipients by Satwani, Prakash, Jin, Zhezhen, Duffy, Deirdre, Morris, Erin, Bhatia, Monica, Garvin, James H, George, Diane, Bradley, Mary Brigid, Harrison, Lauren, Petrillo, Kristen, Schwartz, Joseph, Foley, Sandra, Hawks, Ria, Baxter-Lowe, Lee Ann, Cairo, Mitchell S

“…Abstract Allogeneic hematopoietic stem cell transplantation (allo-HSCT) with myeloablative conditioning is associated with a 10%-40% risk of day +100…”
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Impact of Pretransplantation 18F-fluorodeoxy Glucose–Positron Emission Tomography Status on Outcomes after Allogeneic Hematopoietic Cell Transplantation for Non-Hodgkin Lymphoma by Bachanova, Veronika, Burns, Linda J., Ahn, Kwang Woo, Laport, Ginna G., Akpek, Görgün, Kharfan-Dabaja, Mohamed A., Nishihori, Taiga, Agura, Edward, Armand, Philippe, Jaglowski, Samantha M., Cairo, Mitchell S., Cashen, Amanda F., Cohen, Jonathon B., D'Souza, Anita, Freytes, César O., Gale, Robert Peter, Ganguly, Siddhartha, Ghosh, Nilanjan, Holmberg, Leona A., Inwards, David J., Kanate, Abraham S., Lazarus, Hillard M., Malone, Adriana K., Munker, Reinhold, Mussetti, Alberto, Norkin, Maxim, Prestidge, Tim D., Rowe, Jacob M., Satwani, Prakash, Siddiqi, Tanya, Stiff, Patrick J., William, Basem M., Wirk, Baldeep, Maloney, David G., Smith, Sonali M., Sureda, Anna M., Carreras, Jeanette, Hamadani, Mehdi

“…Assessment with 18F-fluorodeoxy glucose (FDG)–positron emission tomography (PET) before hematopoietic cell transplantation (HCT) for lymphoma may be prognostic…”
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Efficacy of Treatment Options for Children with Steroid-Refractory Acute Gvhd by Satwani, Prakash, Chaudhury, Sonali, Musat, Mihaela Georgiana, Wehling, Jodie, Shang, Gwen

“…Background: Approximately half of patients with acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic cell transplantation (alloHCT)…”
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