Search Results - "Satoshi Kambayashi"

Decreased sensitivity of cyclin-dependent kinase 4/6 inhibitors, palbociclib and abemaciclib to canine lymphoma cells with high p16 protein expression and low retinoblastoma protein phosphorylation by MAYLINA, Leni, KAMBAYASHI, Satoshi, BABA, Kenji, IGASE, Masaya, MIZUNO, Takuya, OKUDA, Masaru

“…Canine lymphoma/leukemia cell lines with p16 protein expressions: high (17–71 and GL-1) and low (CLBL-1, CLC, Nody-1, and UL-1) were treated in vitro with…”
Get full text

Comparative Studies of Bioactivities and Chemical Components in Fresh and Black Garlics by Matsuse, Kanako, Hirata, Sho, Abdelrahman, Mostafa, Nakajima, Tetsuya, Iuchi, Yoshihito, Kambayashi, Satoshi, Okuda, Masaru, Kazumura, Kimiko, Manochai, Benya, Shigyo, Masayoshi

“…To investigate the bioactivities of fresh garlic and its processed product, black garlic, we conducted comparative analyses of antioxidant, anti-inflammatory,…”
Get full text

Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation by Maylina, Leni, Kambayashi, Satoshi, Baba, Kenji, Okuda, Masaru

“…Cyclin-dependent kinase inhibitor p16 (CDKN2A) primarily functions as a negative regulator of the retinoblastoma protein (pRb) pathway to prevent pRb…”
Get full text

Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone by YAMAMOTO, Hiroka, KIMURA, Kyoga, HORIKIRIZONO, Hiro, TAMURA, Yojiro, KAMBAYASHI, Satoshi, BABA, Kenji, OKUDA, Masaru, MIZUNO, Takuya, IGASE, Masaya

“…A 1-year-old spayed female Miniature Schnauzer had chronic hyponatremia, accompanied by polyuria and polydipsia. Blood tests and urinalysis revealed severe…”
Get full text

Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors by Igase, Masaya, Inanaga, Sakuya, Nishibori, Shoma, Itamoto, Kazuhito, Sunahara, Hiroshi, Nemoto, Yuki, Tani, Kenji, Horikirizono, Hiro, Nakaichi, Munekazu, Baba, Kenji, Kambayashi, Satoshi, Okuda, Masaru, Sakai, Yusuke, Sakurai, Masashi, Kato, Masahiro, Tsukui, Toshihiro, Mizuno, Takuya

“…The anti-programmed death 1 (PD-1) antibody has led to durable clinical responses in a wide variety of human tumors. We have previously developed the caninized…”
Get full text

Microparticle-associated tissue factor activity in dogs with disseminated intravascular coagulation by KOBAYASHI, Kosuke, BABA, Kenji, IGASE, Masaya, MIYAMA, Takako Shimokawa, KAMBAYASHI, Satoshi, OKUDA, Masaru

“…Microparticle (MP)-associated tissue factor (TF) activity in plasma might play a role in human disseminated intravascular coagulation (DIC). The aim of this…”
Get full text

Tissue factor procoagulant activity in the tumor cell lines and plasma of dogs with various malignant tumors by KOBAYASHI, Kosuke, BABA, Kenji, IGASE, Masaya, PRIMARIZKY, Hardany, NEMOTO, Yuki, MIYAMA, Takako SHIMOKAWA, KAMBAYASHI, Satoshi, MIZUNO, Takuya, OKUDA, Masaru

“…Hypercoagulability is a common paraneoplastic complication in dogs with various malignant tumors. Importantly, tissue factor procoagulant activity (TF-PCA)…”
Get full text

MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells by NAGAO, Itsuma, TSUJI, Kanako, GOTO-KOSHINO, Yuko, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, KAMBAYASHI, Satoshi, TOMIYASU, Hirotaka, BABA, Kenji, OKUDA, Masaru

“…Gallbladder mucocele (GBM) is one of the most common gallbladder diseases in dogs. Its pathogenesis has not yet been clarified, but excessive accumulation of a…”
Get full text

Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma by KAMBAYASHI, Satoshi, IGASE, Masaya, KOBAYASHI, Kosuke, KIMURA, Ayana, MIYAMA, Takako SHIMOKAWA, BABA, Kenji, NOGUCHI, Shunsuke, MIZUNO, Takuya, OKUDA, Masaru

“…Hypoxic conditions in various cancers are believed to relate with their malignancy, and hypoxia inducible factor-1α (HIF-1α) has been shown to be a major…”
Get full text

Improvement of anemia in five dogs with nonregenerative anemia treated with allogeneic adipose-derived stem cells by Mizuno, Takuya, Inoue, Misuzu, Kubo, Takeaki, Iwaki, Yoshihide, Kawamoto, Kosuke, Itamoto, Kazuhito, Kambayashi, Satoshi, Igase, Masaya, Baba, Kenji, Okuda, Masaru

“…•Five canine cases with nonregenerative anemia were included in this study.•All were treated with allogeneic adipose-derived stem cells (ADSCs).•All cases…”
Get full text

Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders by IGASE, Masaya, MIYAMA, Takako SHIMOKAWA, KAMBAYASHI, Satoshi, SHIMOYAMA, Yumiko, HIRAOKA, Hiroko, HIRATA, Yumi, IWATA, Miki, BABA, Kenji, MIZUNO, Takuya, OKUDA, Masaru

“…A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb was revealed with bimodal monoclonal gammopathy composed of IgA by…”
Get full text

Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors by Masaya Igase, Sakuya Inanaga, Shoma Nishibori, Kazuhito Itamoto, Hiroshi Sunahara, Yuki Nemoto, Kenji Tani, Hiro Horikirizono, Munekazu Nakaichi, Kenji Baba, Satoshi Kambayashi, Masaru Okuda, Yusuke Sakai, Masashi Sakurai, Masahiro Kato, Toshihiro Tsukui, Takuya Mizuno

“…Background: The anti-programmed death 1 (PD-1) antibody has led to durable clinical responses in a wide variety of human tumors. We have previously developed…”
Get full text

Blockade of isoprenoids biosynthesis by simvastatin induces autophagy-mediated cell death via downstream c-Jun N-terminal kinase activation and cell cycle dysregulation in canine T-cell lymphoma cells by Kobayashi, Kosuke, Baba, Kenji, Kambayashi, Satoshi, Okuda, Masaru

“…Statins are inhibitors of the mevalonic acid pathway that mediates cellular metabolism by producing cholesterol and isoprenoids and are widely used in treating…”
Get full text

Plasma cell‐free DNA in canine lymphoma patients as a novel material for genotyping by Kambayashi, Satoshi, Ono, Nanae, Tone, Tomofumi, Baba, Kenji, Okuda, Masaru

“…Canine lymphoma is a disease with high morbidity and poor long‐term prognosis, despite a high response rate to chemotherapy. In this study, we focused on…”
Get full text

Effect of simvastatin on cell proliferation and Ras activation in canine tumour cells by Kobayashi, Kosuke, Baba, Kenji, Kambayashi, Satoshi, Okuda, Masaru

“…Statins are inhibitors of the mevalonate cascade that is responsible for cholesterol biosynthesis and the formation of intermediate metabolites, farnesyl…”
Get full text

Decreased sensitivity of cyclin-dependent kinase 4/6 inhibitors, palbociclib and abemaciclib to canine lymphoma cells with high p16 protein expression and low retinoblastoma protein phosphorylation by MAYLINA, Leni, KAMBAYASHI, Satoshi, BABA, Kenji, IGASE, Masaya, MIZUNO, Takuya, OKUDA, Masaru

“…Canine lymphoma/leukemia cell lines with p16 protein expressions: high (17-71 and GL-1) and low (CLBL-1, CLC, Nody-1, and UL-1) were treated in vitro with…”
Get full text

Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone by YAMAMOTO, Hiroka, KIMURA, Kyoga, HORIKIRIZONO, Hiro, TAMURA, Yojiro, KAMBAYASHI, Satoshi, BABA, Kenji, OKUDA, Masaru, MIZUNO, Takuya, IGASE, Masaya

“…A 1-year-old spayed female Miniature Schnauzer had chronic hyponatremia, accompanied by polyuria and polydipsia. Blood tests and urinalysis revealed severe…”
Get full text

MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells by NAGAO, Itsuma, TSUJI, Kanako, GOTO-KOSHINO, Yuko, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, KAMBAYASHI, Satoshi, TOMIYASU, Hirotaka, BABA, Kenji, OKUDA, Masaru

“…Gallbladder mucocele (GBM) is one of the most common gallbladder diseases in dogs. Its pathogenesis has not yet been clarified, but excessive accumulation of a…”
Get full text

Abstract 4149: Increased migration ability of osimertinib-resistant EGFR-T790M mutant non-small-cell lung cancer cells by Kambayashi, Satoshi, Koh, Yasuhiro, Ohyama, Maiha, Tanaka, Ayaka, Akamatsu, Hiroaki, Tokudome, Nahomi, Ueda, Hiroki, Yamamoto, Nobuyuki

“…Abstract Background: A third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib is effective against…”
Get full text

Abstract 3797: Non-invasive identification of tumor cells using near infrared composition imaging system by Koh, Yasuhiro, Kambayashi, Satoshi, Akamatsu, Hiroaki, Tokudome, Nahomi, Ueda, Hiroki, Yamamoto, Nobuyuki

“…Abstract BACKGROUND: Circulating tumor cells (CTCs) are expected to be utilized for decision-making in precision cancer medicine and further elucidation of…”
Get full text