Search Results - "Satoshi Futakawa"

Structural basis for specific inhibition of Autotaxin by a DNA aptamer by Kato, Kazuki, Ikeda, Hisako, Miyakawa, Shin, Futakawa, Satoshi, Nonaka, Yosuke, Fujiwara, Masatoshi, Okudaira, Shinichi, Kano, Kuniyuki, Aoki, Junken, Morita, Junko, Ishitani, Ryuichiro, Nishimasu, Hiroshi, Nakamura, Yoshikazu, Nureki, Osamu

“…SELEX selections and crystallographic analyses have allowed development of a DNA aptamer that inhibits autotaxin with high potency and specificity, and…”
Get full text

Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease by Matsuda, Yusaku, Nonaka, Yosuke, Futakawa, Satoshi, Imai, Hirotaka, Akita, Kazumasa, Nishihata, Toshiaki, Fujiwara, Masatoshi, Ali, Yusuf, Bhisitkul, Robert B., Nakamura, Yoshikazu

“…Currently approved therapies for age-related macular degeneration (AMD) are inhibitors against vascular endothelial growth factor (VEGF), which is a major…”
Get full text

α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling by Kitazume, Shinobu, Imamaki, Rie, Ogawa, Kazuko, Komi, Yusuke, Futakawa, Satoshi, Kojima, Soichi, Hashimoto, Yasuhiro, Marth, Jamey D., Paulson, James C., Taniguchi, Naoyuki

“…Antiangiogenesis therapies are now part of the standard repertoire of cancer therapies, but the mechanisms for the proliferation and survival of endothelial…”
Get full text

High affinity sialoside ligands of myelin associated glycoprotein by Zeng, Ying, Rademacher, Christoph, Nycholat, Corwin M., Futakawa, Satoshi, Lemme, Katrin, Ernst, Beat, Paulson, James C.

“…Myelin associated glycoprotein (Siglec-4) is a myelin adhesion receptor, that is, well established for its role as an inhibitor of axonal outgrowth in nerve…”
Get full text

High Throughput ELISAs to Measure a Unique Glycan on Transferrin in Cerebrospinal Fluid : A Possible Extension toward Alzheimer's Disease Biomarker Development by Futakawa, Satoshi, Shirotani, Keiro, Nara, Kiyomitsu, Hoshi, Kyoka, Saito, Toshie, Tohyama, Yuriko, Kitazume, Shinobu, Yuasa, Tatsuhiko, Miyajima, Masakazu, Arai, Hajime, Kuno, Atsushi, Narimatsu, Hisashi, Hashimoto, Yasuhiro

“…We have established high-throughput lectin-antibody ELISAs to measure different glycans on transferrin (Tf) in cerebrospinal fluid (CSF) using lectins and an…”
Get full text

Sialoside Analogue Arrays for Rapid Identification of High Affinity Siglec Ligands by Blixt, Ola, Han, Shoufa, Liao, Liang, Zeng, Ying, Hoffmann, Julia, Futakawa, Satoshi, Paulson, James C

“…The siglec family of sialic acid binding proteins participates in diverse cell surface biology that includes regulation of immune cell signaling and the…”
Get full text

A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH by Futakawa, Satoshi, Nara, Kiyomitsu, Miyajima, Masakazu, Kuno, Atsushi, Ito, Hiromi, Kaji, Hiroyuki, Shirotani, Keiro, Honda, Takashi, Tohyama, Yuriko, Hoshi, Kyoka, Hanzawa, Yusuke, Kitazume, Shinobu, Imamaki, Rie, Furukawa, Katsutoshi, Tasaki, Kazuhiro, Arai, Hiroyuki, Yuasa, Tatsuhiko, Abe, Masafumi, Arai, Hajime, Narimatsu, Hisashi, Hashimoto, Yasuhiro

“…Abstract Idiopathic normal pressure hydrocephalus (iNPH) is an elderly dementia caused by abnormal metabolism in the cerebrospinal fluid (CSF). The tap test is…”
Get full text

β-Galactoside α2,6-Sialyltransferase I Cleavage by BACE1 Enhances the Sialylation of Soluble Glycoproteins: A NOVEL REGULATORY MECHANISM FOR α2,6-SIALYLATION by Sugimoto, Ichiro, Futakawa, Satoshi, Oka, Ritsuko, Ogawa, Kazuko, Marth, Jamey D, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro, Kitazume, Shinobu

“…BACE1 (β-site amyloid precursor protein-cleaving enzyme-1) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a neurotoxic…”
Get full text

beta -Galactoside alpha 2,6-Sialyltransferase I Cleavage by BACE1 Enhances the Sialylation of Soluble Glycoproteins: A NOVEL REGULATORY MECHANISM FOR alpha 2,6-SIALYLATION by Sugimoto, Ichiro, Futakawa, Satoshi, Oka, Ritsuko, Ogawa, Kazuko, Marth, Jamey D, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro, Kitazume, Shinobu

“…BACE1 ( beta -site amyloid precursor protein-cleaving enzyme-1) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a…”
Get full text

Molecular insights into beta -galactoside alpha 2,6-sialyltransferase secretion in vivo by Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Futakawa, Satoshi, Hagiwara, Yoshiaki, Takikawa, Hajime, Kato, Michio, Kasahara, Akinori, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro

“…beta -Galactoside alpha 2,6-sialyltransferase (ST6Gal I), which is highly expressed in the liver, is mainly cleaved by Alzheimer's beta -site amyloid precursor…”
Get full text

Molecular insights into β-galactoside α2,6-sialyltransferase secretion in vivo by Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Futakawa, Satoshi, Hagiwara, Yoshiaki, Takikawa, Hajime, Kato, Michio, Kasahara, Akinori, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro

“…β-Galactoside α2,6-sialyltransferase (ST6Gal I), which is highly expressed in the liver, is mainly cleaved by Alzheimer's β-site amyloid precursor…”
Get full text

Development of sandwich enzyme-linked immunosorbent assay systems for plasma β-galactoside α2,6-sialyltransferase, a possible hepatic disease biomarker by Futakawa, Satoshi, Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Hagiwara, Yoshiaki, Kinoshita, Akinori, Miyashita, Kazuya, Hashimoto, Yasuhiro

“…Previous reports, including our work, have shown that plasma β-galactoside α2,6-sialyltransferase (ST6Gal I) activity is significantly increased in particular…”
Get full text

Development of sandwich enzyme-linked immunosorbent assay systems for plasma beta -galactoside alpha 2,6-sialyltransferase, a possible hepatic disease biomarker by Futakawa, Satoshi, Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Hagiwara, Yoshiaki, Kinoshita, Akinori, Miyashita, Kazuya, Hashimoto, Yasuhiro

“…Previous reports, including our work, have shown that plasma beta - galactoside alpha 2,6-sialyltransferase (ST6Gal I) activity is significantly increased in…”
Get full text

Development of sandwich enzyme-linked immunosorbent assay systems for plasma beta-galactoside alpha2,6-sialyltransferase, a possible hepatic disease biomarker by Futakawa, Satoshi, Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Hagiwara, Yoshiaki, Kinoshita, Akinori, Miyashita, Kazuya, Hashimoto, Yasuhiro

“…Previous reports, including our work, have shown that plasma beta-galactoside alpha2,6-sialyltransferase (ST6Gal I) activity is significantly increased in…”
Get full text

Development of sandwich enzyme-linked immunosorbent assay systems for plasma P-galactoside a2,6-sialyltransferase, a possible hepatic disease biomarker by FUTAKAWA, Satoshi, KITAZUME, Shinobu, OKA, Ritsuko, OGAWA, Kazuko, HAGIWARA, Yoshiaki, KINOSHITA, Akinori, MIYASHITA, Kazuya, HASHIMOTO, Yasuhiro

Get full text

α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling by Shinobu Kitazume, Rie Imamaki, Kazuko Ogawa, Yusuke Komi, Satoshi Futakawa, Soichi Kojima, Yasuhiro Hashimoto, Jamey D. Marth, James C. Paulson, Naoyuki Taniguchi

“…Antiangiogenesis therapies are now part of the standard repertoire of cancer therapies, but the mechanisms for the proliferation and survival of endothelial…”
Get full text

β-Galactoside α2,6-Sialyltransferase I Cleavage by BACE1 Enhances the Sialylation of Soluble Glycoproteins by Ichiro Sugimoto, Satoshi Futakawa, Ritsuko Oka, Kazuko Ogawa, Jamey D. Marth, Eiji Miyoshi, Naoyuki Taniguchi, Yasuhiro Hashimoto, Shinobu Kitazume

“…BACE1 ( β -site a myloid precursor protein- c leaving e nzyme- 1 ) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a…”
Get full text

β-Galactoside α2,6-Sialyltransferase I Cleavage by BACE1 Enhances the Sialylation of Soluble Glycoproteins by Sugimoto, Ichiro, Futakawa, Satoshi, Oka, Ritsuko, Ogawa, Kazuko, Marth, Jamey D., Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro, Kitazume, Shinobu

“…BACE1 (β-site amyloid precursor protein-cleaving enzyme-1) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a neurotoxic…”
Get full text

Beta-galactoside alpha2,6-sialyltransferase I cleavage by BACE1 enhances the sialylation of soluble glycoproteins. A novel regulatory mechanism for alpha2,6-sialylation by Sugimoto, Ichiro, Futakawa, Satoshi, Oka, Ritsuko, Ogawa, Kazuko, Marth, Jamey D, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro, Kitazume, Shinobu

“…BACE1 (beta-site amyloid precursor protein-cleaving enzyme-1) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a…”
Get full text

Development of candidate biomarkers for dementia: Cerebrospinal fluid-specific carbohydrate side chains by Shirotani, Keiro, Futakawa, Satoshi, Kuno, Atsushi, Ito, Hiromi, Matsuzaki, Hideki, Hirabayashi, Jun, Narimatsu, Hisashi, Saito, Yukari, Saito, Toshie, Miyajima, Masakazu, Arai, Hajime, Furukawa, Katsutoshi, Arai, Hiroyuki, Hashimoto, Yasuhiro

Get full text