Search Results - "Satoru Kajitani, Gustavo"
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Inflammation response, oxidative stress and DNA damage caused by urban air pollution exposure increase in the lack of DNA repair XPC protein
Published in Environment international (01-12-2020)“…•PM2.5 inflammatory response has been studied on mice with or without XPC protein.•XPC-knockout mice show an increased oxidative stress response to PM2.5…”
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DNA Damage Induced by Late Spring Sunlight in Antarctica
Published in Photochemistry and photobiology (01-11-2020)“…Sunlight ultraviolet (UV) radiation constitutes an important environmental genotoxic agent that organisms are exposed to, as it can damage DNA directly,…”
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Biomass burning in the Amazon region causes DNA damage and cell death in human lung cells
Published in Scientific reports (07-09-2017)“…Most of the studies on air pollution focus on emissions from fossil fuel burning in urban centers. However, approximately half of the world's population is…”
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NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells
Published in Oncotarget (26-07-2016)“…Cancer is a leading cause of death worldwide, and while great advances have been made particularly in chemotherapy, many types of cancer still present a dismal…”
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Cockayne Syndrome: The many challenges and approaches to understand a multifaceted disease
Published in Genetics and molecular biology (01-01-2020)“…The striking and complex phenotype of Cockayne syndrome (CS) patients combines progeria-like features with developmental deficits. Since the establishment of…”
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Extracellular vesicles in neurodegenerative, mental, and other neurological disorders: Perspectives into mechanisms, biomarker potential, and therapeutic implications
Published in Current topics in membranes (2024)“…Extracellular vesicles (EVs) are produced, secreted, and targeted by most human cells, including cells that compose nervous system tissues. EVs carry several…”
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Transcription blockage by DNA damage in nucleotide excision repair-related neurological dysfunctions
Published in Seminars in cell & developmental biology (01-06-2021)“…Human genetic syndromes deficient in nucleotide excision repair (NER), such as xeroderma pigmentosum and Cockayne syndrome, may present neurological…”
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miR-9-5p is Downregulated in Serum Extracellular Vesicles of Patients Treated with Biperiden After Traumatic Brain Injury
Published in Molecular neurobiology (01-11-2024)“…Traumatic brain injury (TBI) is a prevalent and debilitating condition, which often leads to the development of post-traumatic epilepsy (PTE), a condition that…”
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Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model
Published in Aging (Albany, NY.) (15-10-2021)“…Cockayne syndrome (CS) is a rare, autosomal genetic disorder characterized by premature aging-like features, such as cachectic dwarfism, retinal atrophy, and…”
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