Search Results - "Satonaka, Hiroshi"

Eucommia ulmoides (Tochu) and its extract geniposidic acid reduced blood pressure and improved renal hemodynamics by Ishimitsu, Akira, Tojo, Akihiro, Satonaka, Hiroshi, Ishimitsu, Toshihiko

“…Eucommia ulmoides leaves are used as Tochu tea, which has a blood pressure lowering effect of unknown mechanism. The effects of Tochu tea and its component,…”
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V-ATPase blockade reduces renal gluconeogenesis and improves insulin secretion in type 2 diabetic rats by Hirao, Jun, Tojo, Akihiro, Hatakeyama, Saaya, Satonaka, Hiroshi, Ishimitsu, Toshihiko

“…Vacuolar H -adenosine triphosphatase (V-ATPase) stimulates vesicular acidification that may activate cytoplasmic enzymes, hormone secretion and membrane…”
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Optimal blood pressure targets for patients with hypertension: a systematic review and meta-analysis by Sakima, Atsushi, Satonaka, Hiroshi, Nishida, Norifumi, Yatsu, Keisuke, Arima, Hisatomi

“…Optimal blood pressure (BP) targets for hypertension have been an important clinical issue but have been elusive. The Systolic Blood Pressure Intervention…”
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Severe Acute Interstitial Nephritis Induced by α-glucosidase Inhibitor Miglitol in an Elderly Patient with Type 2 Diabetic Nephropathy by Ono, Kazutoshi, Masuda, Takahiro, Ono, Yuko, Hishida, Erika, Yoshizawa, Hiromichi, Imai, Toshimi, Satonaka, Hiroshi, Akimoto, Tetsu, Nagata, Daisuke

“…A 79-year-old male patient with type 2 diabetic nephropathy and hypertension was admitted to our hospital because of acute kidney injury with significantly…”
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Decreased Podocyte Vesicle Transcytosis and Albuminuria in APC C-Terminal Deficiency Mice with Puromycin-Induced Nephrotic Syndrome by Hatakeyama, Saaya, Tojo, Akihiro, Satonaka, Hiroshi, Yamada, Nami O, Senda, Takao, Ishimitsu, Toshihiko

“…In minimal change nephrotic syndrome, podocyte vesicle transport is enhanced. Adenomatous polyposis coli (APC) anchors microtubules to cell membranes and plays…”
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Involvement of P2Y12 receptor in vascular smooth muscle inflammatory changes via MCP-1 upregulation and monocyte adhesion by Satonaka, Hiroshi, Nagata, Daisuke, Takahashi, Masao, Kiyosue, Arihiro, Myojo, Masahiro, Fujita, Daishi, Ishimitsu, Toshihiko, Nagano, Tetsuo, Nagai, Ryozo, Hirata, Yasunobu

“…Antiplatelet drugs, frequently used for cardiovascular events with thrombotic involvement, are also regarded as possible promising agents for cardiovascular…”
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Gestational Hypertension as Risk Factor of Hypertension in Middle-Aged and Older Women by Watanabe, Mariko, Sairenchi, Toshimi, Nishida, Keiko, Uchiyama, Koji, Haruyama, Yasuo, Satonaka, Hiroshi, Ishimitsu, Toshihiko, Yasu, Takanori, Fukasawa, Ichio, Kobashi, Gen

“…The association of gestational hypertension (GH) with future hypertension in Japanese women is unclear. Hence, this study aimed to examine the association…”
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Role of circulating endothelial progenitors in responsiveness to erythropoiesis-stimulating agents in hemodialysis patients by Ishimitsu, Akira, Satonaka, Hiroshi, Furuichi, Masahito, Murayama, Yoshiki, Tojo, Akihiro, Ishimitsu, Toshihiko

“…BackgroundThough treatment of anemia in chronic kidney disease (CKD) patients has been improved remarkably by erythropoiesis-stimulating agents (ESA),…”
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AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation by Nagata, Daisuke, Takeda, Ryo, Sata, Masataka, Satonaka, Hiroshi, Suzuki, Etsu, Nagano, Tetsuo, Hirata, Yasunobu

“…AMP-activated protein kinase (AMPK) is a stress-activated protein kinase that works as a metabolic sensor of cellular ATP levels. Here, we investigated whether…”
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Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells by Myojo, Masahiro, Nagata, Daisuke, Fujita, Daishi, Kiyosue, Arihiro, Takahashi, Masao, Satonaka, Hiroshi, Morishita, Yoshiyuki, Akimoto, Tetsu, Nagai, Ryozo, Komuro, Issei, Hirata, Yasunobu

“…Because endothelial nitric oxide synthase (eNOS) has anti-inflammatory and anti-arteriosclerotic functions, it has been recognized as one of the key molecules…”
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A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell by Nagata, Daisuke, Kiyosue, Arihiro, Takahashi, Masao, Satonaka, Hiroshi, Tanaka, Kimie, Sata, Masataka, Nagano, Tetsuo, Nagai, Ryozo, Hirata, Yasunobu

“…The inhibition of apoptotic changes in vascular endothelial cells is important for preventing vascular damage from hypoxia. AMP-activated protein kinase (AMPK)…”
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Aldosterone-induced osteopontin gene transcription in vascular smooth muscle cells involves glucocorticoid response element by Kiyosue, Arihiro, Nagata, Daisuke, Myojo, Masahiro, Sato, Tomohiko, Takahashi, Masao, Satonaka, Hiroshi, Nagai, Ryozo, Hirata, Yasunobu

“…Osteopontin (OPN) is known to be one of the cytokines that is involved in the vascular inflammation caused by aldosterone (Aldo). Previous reports have shown…”
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Effects of atorvastatin and ezetimibe on endothelial function in dyslipidemic patients with chronic kidney disease by Ishimitsu, Toshihiko, Ohno, Eri, Ueno, Yasuhiko, Onoda, Shou, Nagase, Akihiko, Ohira, Takehiro, Nakano, Nobuyuki, Satonaka, Hiroshi

“…Backgroud Chronic kidney disease (CKD) is a staple risk factor not only for renal failure but also for cardiovascular diseases. In addition, because…”
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Adrenomedullin Induces Endothelium-Dependent Vasorelaxation via the Phosphatidylinositol 3-Kinase/Akt-Dependent Pathway in Rat Aorta by Nishimatsu, Hiroaki, Suzuki, Etsu, Nagata, Daisuke, Moriyama, Nobuo, Satonaka, Hiroshi, Walsh, Kenneth, Sata, Masataka, Kangawa, Kenji, Matsuo, Hisayuki, Goto, Atsuo, Kitamura, Tadaichi, Hirata, Yasunobu

“…ABSTRACT—To study the mechanisms by which adrenomedullin (AM) induces endothelium-dependent vasorelaxation, we examined whether AM-induced…”
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Blockade of endogenous cytokines mitigates neointimal formation in obese Zucker rats by TAKEDA, Ryo, SUZUKI, Etsu, SATONAKA, Hiroshi, OBA, Shigeyoshi, NISHIMATSU, Hiroaki, OMATA, Masao, FUJITA, Toshiro, NAGAI, Ryozo, HIRATA, Yasunobu

“…It is well known that diabetes mellitus is a major risk factor for vascular diseases such as atherosclerosis and restenosis after angioplasty. It has become…”
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Virus Removal and Eradication by Modified Double Filtration Plasmapheresis Decreases Factor XIII Levels by Hanafusa, Norio, Satonaka, Hiroshi, Doi, Kent, Noiri, Eisei, Fujita, Toshiro

“…Factor XIII (FXIII) deficiency increases the chance for pathological bleeding, but this disorder cannot be detected by routine laboratory tests. Virus removal…”
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Transcriptional Activation of the cyclin D1 Gene Is Mediated by Multiple Cis-Elements, Including SP1 Sites and a cAMP-responsive Element in Vascular Endothelial Cells by Nagata, Daisuke, Suzuki, Etsu, Nishimatsu, Hiroaki, Satonaka, Hiroshi, Goto, Atsuo, Omata, Masao, Hirata, Yasunobu

“…In an attempt to examine the mechanisms by which transcriptional activity of the cyclin D1 promoter is regulated in vascular endothelial cells (EC), we…”
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Myocyte Enhancer Factor 2 Mediates Vascular Inflammation via the p38-Dependent Pathway by Suzuki, Etsu, Satonaka, Hiroshi, Nishimatsu, Hiroaki, Oba, Shigeyoshi, Takeda, Ryo, Omata, Masao, Fujita, Toshiro, Nagai, Ryozo, Hirata, Yasunobu

“…Although it has been established that myocyte enhancer factor 2 (MEF2) plays pivotal roles in the development of the cardiovascular system as well as skeletal…”
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Effect of Tochu Extract and Its Component Geniposidic Acid on Renal Hemodynamics and Hypertensive Renal Damage: PO1824 by Tojo, Akihiro, Satonaka, Hiroshi, Ishimitsu, Toshihiko

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Rituximab in treatment of anti-GBM antibody glomerulonephritis: A case report and literature review by Uematsu-Uchida, Mayu, Ohira, Takehiro, Tomita, Shigeki, Satonaka, Hiroshi, Tojo, Akihiro, Ishimitsu, Toshihiko

“…Anti-glomerular basement membrane (GBM) disease is a T cell-mediated disease that has a poor prognosis with conventional therapy. We tested rituximab as a…”
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