Search Results - "Satohisa, Seiro"

ASPP2 suppression promotes malignancy via LSR and YAP in human endometrial cancer by Konno, Takumi, Kohno, Takayuki, Okada, Tadahi, Shimada, Hiroshi, Satohisa, Seiro, Kikuchi, Shin, Saito, Tsuyoshi, Kojima, Takashi

“…Apoptosis-stimulating p53 protein 2 (ASPP2) is an apoptosis inducer that acts via binding with p53 and epithelial polarity molecule PAR3. Lipolysis-stimulated…”
Get full text

Rap1GAP inhibits tumor progression in endometrial cancer by Tamate, Masato, Tanaka, Ryoichi, Osogami, Hiroyuki, Matsuura, Motoki, Satohisa, Seiro, Iwasaki, Masahiro, Saito, Tsuyoshi

“…Endometrioid adenocarcinoma (EAC) is a common endometrial cancer with recent dramatic increases in incidence. Previous findings indicate that Rap1GAP acts as a…”
Get full text

Possibility of Targeting Claudin-2 in Therapy for Human Endometrioid Endometrial Carcinoma by Okada, Tadahi, Konno, Takumi, Kohno, Takayuki, Shimada, Hiroshi, Saito, Kimihito, Satohisa, Seiro, Saito, Tsuyoshi, Kojima, Takashi

“…Claudin-2 (CLDN-2) is a leaky-type tight junction protein, and its overexpression increases tumorigenesis of some types of cancer cells. In the present study,…”
Get more information

Efficacy of liquid‐based genetic diagnosis of endometrial cancer by Matsuura, Motoki, Yamaguchi, Kiyoshi, Tamate, Masato, Satohisa, Seiro, Teramoto, Mizue, Iwasaki, Masahiro, Sugita, Shintaro, Hasegawa, Tadashi, Koubo, Rika, Takane, Kiyoko, Ikenoue, Tsuneo, Furukawa, Yoichi, Saito, Tsuyoshi

“…Although liquid‐based cytology (LBC) has increased the sensitivity of cytological diagnosis of endometrial cancer (EC) compared with conventional smear…”
Get full text

Localization of Tricellular Tight Junction Molecule LSR at Midbody and Centrosome During Cytokinesis in Human Epithelial Cells by Konno, Takumi, Kohno, Takayuki, Kikuchi, Shin, Shimada, Hiroshi, Satohisa, Seiro, Takano, Kenichi, Saito, Tsuyoshi, Kojima, Takashi

“…Epithelial integrity and barrier function are maintained during cytokinesis in vertebrate epithelial tissues. The changes in localization and the roles of…”
Get full text

Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer by Shimada, Hiroshi, Abe, Shyuetsu, Kohno, Takayuki, Satohisa, Seiro, Konno, Takumi, Takahashi, Syunta, Hatakeyama, Tsubasa, Arimoto, Chihiro, Kakuki, Takuya, Kaneko, Yakuto, Takano, Ken-ichi, Saito, Tsuyoshi, Kojima, Takashi

“…Lipolysis-stimulated lipoprotein receptor (LSR) is a unique molecule of tricellular contacts of normal and cancer cells. We investigated how the loss of LSR…”
Get full text

The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells by Shimada, Hiroshi, Satohisa, Seiro, Kohno, Takayuki, Takahashi, Syunta, Hatakeyama, Tsubasa, Konno, Takumi, Tsujiwaki, Mitsuhiro, Saito, Tsuyoshi, Kojima, Takashi

“…Lipolysis-stimulated lipoprotein receptor (LSR) has been identified as a novel molecular constituent of tricellular contacts that have a barrier function for…”
Get full text

The tight-junction protein claudin-6 induces epithelial differentiation from mouse F9 and embryonic stem cells by Sugimoto, Kotaro, Ichikawa-Tomikawa, Naoki, Satohisa, Seiro, Akashi, Yushi, Kanai, Risa, Saito, Tsuyoshi, Sawada, Norimasa, Chiba, Hideki

“…During epithelialization, cell adhesions and polarity must be established to maintain tissue assemblies and separate the biological compartments in the body…”
Get full text

Epithelial barrier dysfunction and cell migration induction via JNK/cofilin/actin by angubindin-1 by Konno, Takumi, Kohno, Takayuki, Kikuchi, Shin, Shimada, Hiroshi, Satohisa, Seiro, Saito, Tsuyoshi, Kondoh, Masuo, Kojima, Takashi

“…Angulin-1/LSR is a tricellular tight junction molecule, that plays an important role in maintaining the epithelial and endothelial barriers. The actin…”
Get full text

Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer by Shimada, Hiroshi, Satohisa, Seiro, Kohno, Takayuki, Konno, Takumi, Takano, Ken-Ichi, Takahashi, Syunta, Hatakeyama, Tsubasa, Arimoto, Chihiro, Saito, Tsuyoshi, Kojima, Takashi

“…Lipolysis-stimulated lipoprotein receptor (LSR) is a novel molecule present at tricellular contacts which recruits tricellulin (TRIC), a molecular component of…”
Get full text

ASPP2 suppression promotes malignancy via LSR and YAP in human endometrial cancer by Konno, Takumi, Kohno, Takayuki, Okada, Tadahi, Shimada, Hiroshi, Satohisa, Seiro, Kikuchi, Shin, Saito, Tsuyoshi, Kojima, Takashi

Get full text

Palonosetron in combination with 1-day versus 3-day dexamethasone for prevention of nausea and vomiting following paclitaxel and carboplatin in patients with gynecologic cancers: A randomized, multicenter, phase-II trial by Matsuura, Motoki, Satohisa, Seiro, Teramoto, Mizue, Tanaka, Ryoichi, Iwasaki, Masahiro, Nishikawa, Akira, Mizunuma, Masahiro, Tanaka, Satoshi, Hayakawa, Osamu, Saito, Tsuyoshi

“…Aim Chemotherapy‐induced nausea and vomiting (CINV) can affect a patient's quality of life, leading to poor compliance with further treatments. Previous…”
Get full text

Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation by Nishiura, Keisuke, Sugimoto, Kotaro, Satohisa, Seiro, Chiba, Hideki, Ichikawa-Tomikawa, Naoki

“…Tight junctions are intercellular junctions localized at the most apical end of the lateral plasma membrane. They consist of four kinds of transmembrane…”
Get full text

Low-dose SN-38 with paclitaxel induces lethality in human uterine cervical adenocarcinoma cells by increasing caspase activity by Teramoto, Mizue, Suzuki, Takahiro, Satohisa, Seiro, Akashi, Yushi, Matsuura, Motoki, Suzuki, Miwa, Tanaka, Ryoichi, Saito, Tsuyoshi

“…Combination of anticancer drugs may provide a rational molecular basis for novel chemotherapeutic strategies. Paclitaxel and SN-38 (an active metabolite of…”
Get full text

Hypermethylation in promoter region of retinoic acid receptor-beta gene and immunohistochemical findings on retinoic acid receptors in carcinogenesis of endometrium by Li, Rong, Saito, Tsuyoshi, Tanaka, Ryoichi, Satohisa, Seiro, Adachi, Katsuya, Horie, Miyabi, Akashi, Yushi, Kudo, Ryuichi

“…In the present study, we analyzed the immunohistochemical findings for the RA receptor (RAR), retinoic X receptor (RXR) and hypermethylation of promoter-region…”
Get full text

Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta by Wang, Wen, Feng, Lin, Zhang, Honghai, Hachy, Stephanie, Satohisa, Seiro, Laurent, Louise C, Parast, Mana, Zheng, Jing, Chen, Dong-bao

“…Context: Placental angiogenesis contributes to the pathogenesis of preeclampsia (PE) that affects 5–8% of all human pregnancies. MicroRNA (miRNA) are a class…”
Get full text

BAG3-mediated Mcl-1 stabilization contributes to drug resistance via interaction with USP9X in ovarian cancer by HABATA, SHUTARO, IWASAKI, MASAHIRO, SUGIO, ASUKA, SUZUKI, MIWA, TAMATE, MASATO, SATOHISA, SEIRO, TANAKA, RYOICHI, SAITO, TSUYOSHI

“…Paclitaxel in combination with carboplatin improves survival among patients with susceptible ovarian cancers, but no strategy has been established against…”
Get full text

ERα increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3 by Abe, Shuetsu, Iwasaki, Masahiro, Habata, Shutaro, Mariya, Tasuku, Tamate, Masato, Matsuura, Motoki, Satohisa, Seiro, Saito, Tsuyoshi

“…Endometrial cancer is a leading cause of cancer-associated mortality in women and has a poor prognosis in advanced stages. Our previous study revealed that…”
Get full text

ER[alpha] increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3 by Abe, Shuetsu, Iwasaki, Masahiro, Habata, Shutaro, Mariya, Tasuku, Tamate, Masato, Matsuura, Motoki, Satohisa, Seiro, Saito, Tsuyoshi

“…Endometrial cancer is a leading cause of cancer-associated mortality in women and has a poor prognosis in advanced stages. Our previous study revealed that…”
Get full text

BAG3 increases the invasiveness of uterine corpus carcinoma cells by suppressing miR-29b and enhancing MMP2 expression by HABATA, SHUTARO, IWASAKI, MASAHIRO, SUGIO, ASUKA, SUZUKI, MIWA, TAMATE, MASATO, SATOHISA, SEIRO, TANAKA, RYOICHI, SAITO, TSUYOSHI

“…Approximately 30% of uterine corpus carcinomas are diagnosed at an advanced stage and have a poor prognosis. Our previous study indicated that BCL2-associated…”
Get full text