Search Results - "Satoh, Takayuki"
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Upregulation of p27 cyclin-dependent kinase inhibitor and a C-terminus truncated form of p27 contributes to G1 phase arrest
Published in Scientific reports (10-06-2016)“…Potent anti-cancer compounds FR901464 and its methyl-ketal derivative spliceostatin A (SSA) inhibit cell cycle progression at G1 and G2/M phases. These…”
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A Truncated Form of the p27 Cyclin-Dependent Kinase Inhibitor Translated from Pre-mRNA Causes G2-Phase Arrest
Published in Molecular and cellular biology (01-11-2022)“…Pre-mRNA splicing is an indispensable mechanism for eukaryotic gene expression. Splicing inhibition causes cell cycle arrest at the G 1 and G 2 /M phases, and…”
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IL-17/IFN-γ double producing CD8+ T (Tc17/IFN-γ) cells: A novel cytotoxic T-cell subset converted from Tc17 cells by IL-12
Published in International immunology (01-12-2011)“…It has been reported that IFN-γ-producing CD8+ T (Tc1) cells express cytotoxic molecules such as perforin and granzyme B to exhibit higher cytotoxicity against…”
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FGF induces oscillations of Hes1 expression and Ras/ERK activation
Published in Current biology (22-04-2008)“…Many biological processes, such as circadian rhythms and somite segmentation [1], are regulated by molecular clocks. During somitogenesis, mRNAs for Notch…”
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The ERK-MAPK Pathway Regulates Longevity through SKN-1 and Insulin-like Signaling in Caenorhabditis elegans
Published in The Journal of biological chemistry (24-09-2010)“…It has not been determined yet whether the ERK-MAPK pathway regulates longevity of metazoans. Here, we show that the Caenorhabditis elegans ERK cascade…”
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U2 snRNP is required for expression of the 3' end of genes
Published in PloS one (20-05-2014)“…Pre-mRNA in eukaryotes is subjected to mRNA processing, which includes capping, polyadenylation, and splicing. Transcription and mRNA processing are coupled,…”
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Down-regulation of the PI3-kinase/Akt pathway by ERK MAP kinase in growth factor signaling
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-09-2008)“…The ERK MAP kinase and PI3-kinase/Akt pathways are major intracellular signaling modules, which are known to regulate diverse cellular processes including cell…”
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Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein
Published in International journal of molecular sciences (09-02-2015)“…In eukaryotes, pre-mRNA splicing is an essential step for gene expression. We have been analyzing post-splicing intron turnover steps in higher eukaryotes…”
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CrkL is a novel target of Sprouty2 in fibroblast growth factor signaling
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-03-2010)“…Sprouty, an inhibitor of receptor tyrosine kinase signaling, plays an important role in the regulation of a wide variety of biological processes. Although it…”
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Establishment of a stable T lymphoma cell line transduced with HLA-A24:02-restricted WT1-specific TCR genes and its application to antigen-specific immunomonitoring
Published in Biomedical research (Tokyo) (01-02-2013)“…Wilms' tumor gene 1 (WT1) has been proposed as an attractive target for cancer immunotherapy. A natural 9-mer peptide (CYTWNQMNL), which bound to human…”
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Control of Self-Formed GaAs Nanoholes Combined with Embedded InAs Quantum Dots
Published in Japanese Journal of Applied Physics (01-04-2005)“…We investigated the self-formation of GaAs nanoholes combined with embedded InAs quantum dots (QDs), grown by molecular beam epitaxy using the…”
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Anti‐IL‐6 receptor mAb eliminates myeloid‐derived suppressor cells and inhibits tumor growth by enhancing T‐cell responses
Published in European journal of immunology (01-08-2012)“…CD11b+Gr‐1+ immature myeloid cells (ImCs), which are abnormally increased in tumor‐bearing mice, were classified into three different subsets according to…”
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The development of IL‐17/IFN‐γ‐double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter
Published in European journal of immunology (01-09-2012)“…The plasticity of T lymphocytes induced by epigenetic modifications of gene promoters may play a pivotal role in controlling their effector functions, which…”
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A Truncated Form of the p27 Cyclin-Dependent Kinase Inhibitor Translated from Pre-mRNA Causes G 2 -Phase Arrest
Published in Molecular and cellular biology (17-11-2022)“…Pre-mRNA splicing is an indispensable mechanism for eukaryotic gene expression. Splicing inhibition causes cell cycle arrest at the G and G /M phases, and this…”
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U2 snRNP is required for the phosphorylation of Pol II CTD Ser2 and efficient transcription elongation (560.4)
Published in The FASEB journal (01-04-2014)“…Pre‐mRNA in eukaryotes is subjected to post‐transcriptional modifications, such as capping, polyadenylation and splicing. Transcription and…”
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The development of IL ‐17/ IFN ‐γ‐double producing CTL s from T c17 cells is driven by epigenetic suppression of S ocs3 gene promoter
Published in European journal of immunology (01-09-2012)“…The plasticity of T lymphocytes induced by epigenetic modifications of gene promoters may play a pivotal role in controlling their effector functions, which…”
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The development of IL-17/IFN-[gamma]-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter
Published in European journal of immunology (01-09-2012)“…The plasticity of T lymphocytes induced by epigenetic modifications of gene promoters may play a pivotal role in controlling their effector functions, which…”
Get full text
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