Search Results - "Sato, Tokiharu"
-
1
Lesion Area in the Cerebral Cortex Determines the Patterns of Axon Rewiring of Motor and Sensory Corticospinal Tracts After Stroke
Published in Frontiers in neuroscience (11-10-2021)“…The corticospinal tract (CST) is an essential neural pathway for reorganization that recovers motor functions after brain injuries such as stroke. CST…”
Get full text
Journal Article -
2
Cerebrospinal fluid-contacting neuron tracing reveals structural and functional connectivity for locomotion in the mouse spinal cord
Published in eLife (21-02-2023)“…Cerebrospinal fluid-contacting neurons (CSF-cNs) are enigmatic mechano- or chemosensory cells lying along the central canal of the spinal cord. Recent studies…”
Get full text
Journal Article -
3
The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication
Published in Scientific reports (03-09-2018)“…Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting…”
Get full text
Journal Article -
4
Direct Comparison of Odor Responses of Homologous Glomeruli in the Medial and Lateral Maps of the Mouse Olfactory Bulb
Published in eNeuro (01-03-2020)“…Olfactory sensory neurons (OSNs) expressing same-type odorant receptors typically project to a pair of glomeruli in the medial and lateral sides of the…”
Get full text
Journal Article -
5
Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions
Published in Haematologica (Roma) (01-09-2012)“…NKG2D is an activating receptor expressed by natural killer and T cells, which have crucial functions in tumor and microbial immunosurveillance. Several…”
Get full text
Journal Article -
6
Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice
Published in FEBS letters (14-09-2015)“…•JSAP1 and JLP are essential for mouse cerebellar Purkinje cell (PC) survival.•JSAP1/JLP-deficient PCs exhibit axonal dystrophy, followed by cell…”
Get full text
Journal Article -
7
Expression and distribution of JNK/SAPK‐associated scaffold protein JSAP1 in developing and adult mouse brain
Published in Journal of neurochemistry (01-06-2006)“…The c‐Jun N‐terminal kinase (JNK) is one of the three major mitogen‐activated protein kinases (MAPKs) playing key roles in various cellular processes in…”
Get full text
Journal Article -
8
JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-09-2014)“…The ADP‐ribosylation factor 6 (ARF6) GTPase is important in cytokinesis and localizes to the midbody. However, the mechanism and regulation of ARF6's…”
Get full text
Journal Article -
9
Narrowly Confined and Glomerulus-Specific Onset Latencies of Odor-Evoked Calcium Transients in the Juxtaglomerular Cells of the Mouse Main Olfactory Bulb
Published in eNeuro (01-01-2019)“…Odor information is transmitted from olfactory sensory neurons to principal neurons at the glomeruli of the olfactory bulb. The intraglomerular neuronal…”
Get full text
Journal Article -
10
Role of plasma membrane localization of the scaffold protein JSAP1 during differentiation of cerebellar granule cell precursors
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-01-2011)“…We previously reported that the scaffold protein c‐Jun NH2‐terminal kinase (JNK)/stress‐activated protein kinase‐associated protein 1 (JSAP1) functions in…”
Get full text
Journal Article -
11
The scaffold protein JLP plays a key role in regulating ultraviolet B‐induced apoptosis in mice
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-04-2014)“…The ultraviolet B (UVB) component of sunlight can cause severe damage to skin cells and even induce skin cancer. Growing evidence indicates that the…”
Get full text
Journal Article -
12
JSAP1/JIP3 Cooperates with Focal Adhesion Kinase to Regulate c-Jun N-terminal Kinase and Cell Migration
Published in The Journal of biological chemistry (11-11-2005)“…c-Jun N-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 (JSAP1) (also termed JNK-interacting protein 3; JIP3) is a member of a…”
Get full text
Journal Article -
13
The scaffold protein JSAP1 regulates proliferation and differentiation of cerebellar granule cell precursors by modulating JNK signaling
Published in Molecular and cellular neuroscience (01-11-2008)“…Cerebellar granule cell precursors (GCPs) proliferate in the outer part of the external granular layer (EGL). They begin their differentiation by exiting the…”
Get full text
Journal Article -
14
Ablation of the scaffold protein JLP causes reduced fertility in male mice
Published in Transgenic research (01-12-2008)“…The specific and efficient activation of mitogen-activated protein kinase (MAPK) signaling modules is mediated, at least in part, by scaffold proteins. c-Jun…”
Get full text
Journal Article -
15
Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death
Published in Neuroscience letters (11-12-2007)“…We previously identified c-Jun NH 2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 (JSAP1, also known as JNK-interacting protein 3)…”
Get full text
Journal Article -
16
Structure, regulation, and function of micro1 in the sea urchin Hemicentrotus pulcherrimus
Published in Development genes and evolution (01-11-2004)“…The animal-vegetal axis of sea urchin embryos is morphologically apparent at the 16-cell stage, when the mesomeres, macromeres, and micromeres align along it…”
Get full text
Journal Article -
17
TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models
Published in Acta neuropathologica (01-10-2023)“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by TDP-43 inclusions in the cortical and spinal motor neurons. It…”
Get full text
Journal Article -
18
CRISPR/CasRx suppresses KRAS-induced brain arteriovenous malformation developed in postnatal brain endothelial cells in mice
Published in JCI insight (22-11-2024)“…Brain arteriovenous malformations (bAVMs) are anomalies forming vascular tangles connecting the arteries and veins, which cause hemorrhagic stroke in young…”
Get full text
Journal Article -
19
JSAP 1 and JLP are required for ARF 6 localization to the midbody in cytokinesis
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-09-2014)“…The ADP ‐ribosylation factor 6 ( ARF 6) GTP ase is important in cytokinesis and localizes to the midbody. However, the mechanism and regulation of ARF 6's…”
Get full text
Journal Article -
20