Search Results - "Sato, Shuichiro"

An Efficient and Practical Method for the Synthesis of the 5-Acylamino-4-(4-pyrimidinyl)isoxazole Derivative AKP-001, a Potent P38 MAP Kinase Inhibitor by Ohta, Shuji, Saito, Takahisa, Kato, Jun-ya, Sato, Shuichiro, Hayashi, Hiroyuki, Hasumi, Koichi

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Antibody response against NY‐ESO‐1 in CHP‐NY‐ESO‐1 vaccinated patients by Kawabata, Ryohei, Wada, Hisashi, Isobe, Midori, Saika, Takashi, Sato, Shuichiro, Uenaka, Akiko, Miyata, Hiroshi, Yasuda, Takushi, Doki, Yuichiro, Noguchi, Yuji, Kumon, Hiromi, Tsuji, Kazuhide, Iwatsuki, Keiji, Shiku, Hiroshi, Ritter, Gerd, Murphy, Roger, Hoffman, Eric, Old, Lloyd J., Monden, Morito, Nakayama, Eiichi

“…NY‐ESO‐1 specific humoral responses are frequently observed in patients with various types of NY‐ESO‐1 antigen expressing tumors. In a large proportion of…”
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Spontaneous remission of a non-small cell lung cancer possibly caused by anti-NY-ESO-1 immunity by Nakamura, Yoichi, Noguchi, Yuji, Satoh, Eiichi, Uenaka, Akiko, Sato, Shuichiro, Kitazaki, Takeshi, Kanda, Tetsuro, Soda, Hiroshi, Nakayama, Eiichi, Kohno, Shigeru

“…Abstract Spontaneous remission of malignant tumors is rare and the biological mechanism of such remission has not been addressed. We report the case of a…”
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NY-ESO-1 expression and immunogenicity in malignant and benign breast tumors by SUGITA, Yurika, WADA, Hisashi, GNJATIC, Sacha, WILLIAMSON, Barbara, SCANLAN, Matthew J, ONO, Toshiro, SAKITA, Isao, YASUI, Masayoshi, MIYOSHI, Yasuo, TAMAKI, Yasuhiro, MATSUURA, Nariaki, NOGUCHI, Shinzaburo, FUJITA, Shoichiro, OLD, Lloyd J, NAKAYAMA, Eiichi, MONDEN, Morito, NAKATA, Tetsuya, SATO, Shuichiro, NOGUCHI, Yuji, JUNGBLUTH, Achim A, YAMAGUCHI, Masae, CHEN, Yao-Tseng, STOCKERT, Elisabeth

“…NY-ESO-1 is a cancer/testis antigen expressed in normal adult tissues solely in the testicular germ cells of normal adults and in various cancers. It induces…”
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XAGE-1 Expression in Non–Small Cell Lung Cancer and Antibody Response in Patients by NAKAGAWA, Kazuhiko, NOGUCHI, Yuji, YOSHINO, Tadashi, YAMASHITA, Kazuki, TSUNODA, Tsukasa, AOE, Motoi, SHIMIZU, Nobuyoshi, NAKAYAMA, Eiichi, UENAKA, Akiko, SATO, Shuichiro, OKUMURA, Hideo, TANAKA, Motoyuki, SHIMONO, Michihide, ELDIB, Mohamed Ali, ONO, Toshiro, OHARA, Nobuya

“…Purpose: XAGE-1 was originally identified by the search for PAGE/GAGE -related genes using expressed sequence tag database and was shown to exhibit…”
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Identification of a CD4 T‐cell epitope in tumor rejection antigen RLakt on BALB/c radiation‐leukemia RL male 1 by Kaya, Savas, Uenaka, Akiko, Sato, Shuichiro, Ono, Toshiro, Aji, Toshiki, Nakayama, Eiichi

“…We have previously shown that the RLakt antigen was predominantly recognized by CD8 cytotoxic T lymphocytes (CTL) in RL male 1‐bearing or ‐rejected syngeneic…”
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NY-ESO-1 Expression and Immunogenicity in Esophageal Cancer by FUJITA, Shoichiro, WADA, Hisashi, YANO, Masahiko, ONO, Toshiro, CHEN, Yao-Tseng, HIGASHIYAMA, Masahiko, GNJATIC, Sacha, OLD, Lloyd J, NAKAYAMA, Eiichi, MONDEN, Morito, JUNGBLUTH, Achim A, SATO, Shuichiro, NAKATA, Tetsuya, NOGUCHI, Yuji, DOKI, Yuichiro, YASUI, Masayoshi, SUGITA, Yurika, YASUDA, Takushi

“…Purpose: Although NY-ESO-1 was isolated from an esophageal carcinoma patient, its expression in this type of cancer and its immunogenicity in esophageal cancer…”
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Decreased expression of B7 costimulatory molecules and major histocompatibility complex class-I in human hepatocellular carcinoma by FUJIWARA, KEISHI, HIGASHI, TOSHIHIRO, NOUSO, KAZUHIRO, NAKATSUKASA, HARUSHIGE, KOBAYASHI, YOSHIYUKI, UEMURA, MASAYUKI, NAKAMURA, SHIN-ICHIRO, SATO, SHUICHIRO, HANAFUSA, TADASHI, YUMOTO, YASUHIRO, NAITO, ICHIRO, SHIRATORI, YASUSHI

“…Background and Aim:  We analyzed the expression of antigen‐processing and antigen‐presenting molecules in surgically resected fresh samples of human…”
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Identification of glioma‐specific RFX4‐E and ‐F isoforms and humoral immune response in patients by Matsushita, Hirokazu, Uenaka, Akiko, Ono, Toshiro, Hasegawa, Kosei, Sato, Shuichiro, Koizumi, Fumihito, Nakagawa, Kazuhiko, Toda, Masahiro, Shingo, Tetsuro, Ichikawa, Tomotsugu, Noguchi, Yuji, Tamiya, Takashi, Furuta, Tomohisa, Kawase, Takeshi, Date, Isao, Nakayama, Eiichi

“…For regulatory factor X4 (RFX4), two alternatively spliced variants, RFX4‐A and ‐B, were reported in the testis. In this study, we identified transcript…”
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HLA-DRB10410-Restricted Recognition of XAGE-1b37-48 Peptide by CD4 T Cells by Morishita, Yoshiyuki, Uenaka, Akiko, Kaya, Savas, Sato, Shuichiro, Aji, Toshiki, Nakayama, Eiichi

“…XAGE‐1b belongs to cancer/testis (CT) antigens, and has been shown to be expressed frequently in lung cancers and to elicit an antibody response in patients…”
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Over-Expression of the Testis-Specific Gene TSGA10 in Cancers and Its Immunogenicity by Tanaka, Ryo, Ono, Toshiro, Sato, Shuichiro, Nakada, Tetsuya, Koizumi, Fumihito, Hasegawa, Kosei, Nakagawa, Kazuhiko, Okumura, Hideo, Yamashita, Toshiharu, Ohtsuka, Mikio, Asagoe, Kenji, Yamasaki, Osamu, Noguchi, Yuji, Iwatsuki, Keiji, Nakayama, Eiichi

“…The TSGA10 gene was originally isolated in normal testis by differential mRNA display. TSGA10 is located on chromosome 2q11.2 and consists of 19 exons…”
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XAGE-1 mRNA Expression in Prostate Cancer and Antibody Response in Patients by Koizumi, Fumihito, Noguchi, Yuji, Saika, Takashi, Nakagawa, Kazuhiko, Sato, Shuichiro, Eldib, Ali Mohamed Ali, Nasu, Yasutomo, Kumon, Hiromi, Nakayama, Eiichi

“…To evaluate the feasibility of cancer vaccine targeting XAGE‐1, we investigated the expression of 4 XAGE‐1 transcript variants and the humoral immune response…”
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Cellular distribution of telomerase reverse transcriptase in human hepatocellular carcinoma by ONISHI, TORU, NOUSO, KAZUHIRO, HIGASHI, TOSHIHIRO, TOSHIKUNI, NOBUYUKI, NAKATSUKASA, HARUSHIGE, KOBAYASHI, YOSHIYUKI, UEMURA, MASAYUKI, YUMOTO, EIICHIRO, FUJIWARA, KEISHI, SATO, SHUICHIRO, NAKAMURA, SHINICHIRO, YOKOYAMA, JUNKO, HANAFUSA, TADASHI, SHIRATORI, YASUSHI

“…Background and Aim:  Telomerase is the enzyme that synthesizes telomeric DNA, and the activation of telomerase is closely related to cellular immortality…”
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Design and synthesis of 5-[(2-chloro-6-fluorophenyl)acetylamino]-3-(4-fluorophenyl)-4-(4-pyrimidinyl)isoxazole (AKP-001), a novel inhibitor of p38 MAP kinase with reduced side effects based on the antedrug concept by Hasumi, Koichi, Sato, Shuichiro, Saito, Takahisa, Kato, Jun-ya, Shirota, Kazuhiko, Sato, Jun, Suzuki, Hiroyuki, Ohta, Shuji

“…Inhibitors of p38 mitogen-activated protein (MAP) kinase, which are closely involved in the production of inflammatory cytokines, are considered promising…”
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Identification of the HERV-K gag antigen in prostate cancer by SEREX using autologous patient serum and its immunogenicity by Ishida, Toshiaki, Obata, Yuichi, Ohara, Nobuya, Matsushita, Hirokazu, Sato, Shuichiro, Uenaka, Akiko, Saika, Takashi, Miyamura, Takako, Chayama, Kosuke, Nakamura, Yurika, Wada, Hisashi, Yamashita, Toshiharu, Morishima, Tsuneo, Old, Lloyd J, Nakayama, Eiichi

“…The prostate cancer HERV-K gag-related NGO-Pr-54 antigen was identified by SEREX analysis using autologous patient serum. NGO-Pr-54 mRNA was observed to be…”
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T cell immunomonitoring and tumor responses in patients immunized with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein by Uenaka, Akiko, Wada, Hisashi, Isobe, Midori, Saika, Takashi, Tsuji, Kazuhide, Sato, Eiichi, Sato, Shuichiro, Noguchi, Yuji, Kawabata, Ryohei, Yasuda, Takushi, Doki, Yuichiro, Kumon, Hiromi, Iwatsuki, Keiji, Shiku, Hiroshi, Monden, Morito, Jungbluth, Achim A, Ritter, Gerd, Murphy, Roger, Hoffman, Eric, Old, Lloyd J, Nakayama, Eiichi

“…We recently showed that vaccination with a complex of cholesterol-bearing hydrophobized pullulan and NY-ESO-1 protein (CHP-NY-ESO-1) elicited antibody…”
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Halogen-Magnesium Exchange Reaction of Iodoindole Derivatives by Sakamoto, Takao, Kondo, Yoshinori, Yoshida, Akihiro, Sato, Shuichiro

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Prolonged survival of patients with lung adenocarcinoma expressing XAGE-1b and HLA class I antigens by Kikuchi, Eiki, Yamazaki, Koichi, Nakayama, Eiichi, Sato, Shuichiro, Uenaka, Akiko, Yamada, Noriyuki, Oizumi, Satoshi, Dosaka-Akita, Hirotoshi, Nishimura, Masaharu

“…XAGE-1b is a cancer/testis antigen that has been shown to be expressed at a significant frequency and to be immunogenic in non-small cell lung cancer (NSCLC)…”
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Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors by Sato, Shuichiro, Noguchi, Yuji, Ohara, Nobuya, Uenaka, Akiko, Shimono, Michihide, Nakagawa, Kazuhiko, Koizumi, Fumihito, Ishida, Toshiaki, Yoshino, Tadashi, Shiratori, Yasushi, Nakayama, Eiichi

“…XAGE-1 is a cancer/testis (CT) antigen and has been shown to be immunogenic in lung cancer patients. Among 4 alternative splicing variants, XAGE-1a, b, c and…”
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Identification of DR9-restricted XAGE antigen on lung adenocarcinoma recognized by autologous CD4 T-cells by SHIMONO, Michihide, UENAKA, Akiko, NOGUCHI, Yuji, SATO, Shuichiro, OKUMURA, Hideo, NAKAGAWA, Kazuhiko, KIURA, Katsuyuki, TANIMOTO, Mitsune, NAKAYAMA, Eiichi

“…We previously demonstrated a dominant IgG response against XAGE-1b antigen in a lung cancer patient by serological analysis of antigens by recombinant…”
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