Search Results - "Sato, Shinobu"

Chemical Modulation of DNA Replication along G‑Quadruplex Based on Topology-Dependent Ligand Binding by Takahashi, Shuntaro, Kotar, Anita, Tateishi-Karimata, Hisae, Bhowmik, Sudipta, Wang, Zi-Fu, Chang, Ta-Chau, Sato, Shinobu, Takenaka, Shigeori, Plavec, Janez, Sugimoto, Naoki

“…Ligands that bind to and stabilize guanine-quadruplex (G4) structures to regulate DNA replication have therapeutic potential for cancer and neurodegenerative…”
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Highly sensitive nuclease assays based on chemically modified DNA or RNA by Sato, Shinobu, Takenaka, Shigeori

“…Nucleolytic enzymes are associated with various diseases, and several methods have been developed for their detection. DNase expression is modulated in such…”
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Substituent effects of cyclic naphthalene diimide on G-quadruplex binding and the inhibition of cancer cell growth by Fukuda, Hikaru, Sato, Shinobu, Zou, Tingting, Higashi, Sen, Takahashi, Osamu, Habu, Manabu, Sasaguri, Masaaki, Tominaga, Kazuhiro, Takenaka, Shigeori, Takeuchi, Hiroshi

“…[Display omitted] •Cyclic naphthalene diimides 1–4 having aliphatic or aromatic part were synthesized.•3 bound to c-myc stronger than to TA-core, whereas 4…”
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Synthesis of a Peptide-Human Telomere DNA Conjugate as a Fluorometric Imaging Reagent for Biological Sodium Ion by SATO, Shinobu, IMAICHI, Yuuki, YOSHIURA, Yukiko, NAKAZAWA, Koji, TAKENAKA, Shigeori

“…A peptide-oligonucleotide conjugate (1) was synthesized by the attachment of FAM, TAMRA, and biotin moieties to a telomere DNA sequence of 5′-TAG GGT TAG GGT…”
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The Interaction of Cyclic Naphthalene Diimide with G-Quadruplex under Molecular Crowding Condition by Zou, Tingting, Sato, Shinobu, Yasukawa, Rui, Takeuchi, Ryusuke, Ozaki, Shunsuke, Fujii, Satoshi, Takenaka, Shigeori

“…G-quadruplex specific targeting molecules, also termed as G4 ligands, are attracting increasing attention for their ability to recognize and stabilize…”
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Membrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related Biomarkers by Kim, Hye Youn, Sato, Shinobu, Takenaka, Shigeori, Lee, Min-Ho

“…Highly sensitive and multiplexed in vitro detection of osteoporosis-related biochemical markers were carried out based on the membrane-based microwave-mediated…”
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Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment by Takahashi, Shuntaro, Bhowmik, Sudipta, Sato, Shinobu, Takenaka, Shigeori, Sugimoto, Naoki

“…The human telomere region is known to contain guanine-rich repeats and form a guanine-quadruplex (G4) structure. As telomeres play a role in the regulation of…”
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Naphthalene Diimides Carrying Two β-Cyclodextrins Prefer Telomere RNA G-Quadruplex Recognition by Zou, Tingting, Sato, Yuka, Kaneyoshi, Shuma, Mano, Kota, Yasukawa, Rui, Nakano, Yoshifumi, Fujii, Satoshi, Sato, Shinobu, Takenaka, Shigeori

“…Newly synthesized naphthalene diimide carrying two β-cyclodextrins (NDI-β-CyDs) showed improved specificity for the parallel G-quadruplex structure alongside…”
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Detection of an aberrant methylation of CDH4 gene in PCR product by ferrocenylnaphthalene diimide-based electrochemical hybridization assay by Sato, Shinobu, Tsueda, Masato, Kanezaki, Yusuke, Takenaka, Shigeori

“…[Display omitted] ► Hybridization efficiency with a DNA probe on the electrode was clarified. ► Hybridization efficiency was 20% for 105-meric PCR product. ►…”
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A Selective G-Quadruplex DNA-Stabilizing Ligand Based on a Cyclic Naphthalene Diimide Derivative by Islam, Md Monirul, Fujii, Satoshi, Sato, Shinobu, Okauchi, Tatsuo, Takenaka, Shigeori

“…A cyclic naphthalene diimide (cyclic NDI, 1), carrying a benzene moiety as linker chain, was synthesized and its interaction with G-quadruplex DNAs of a-core…”
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Oral cancer diagnosis via a ferrocenylnaphthalene diimide-based electrochemical telomerase assay by Mori, Kumiko, Sato, Shinobu, Kodama, Masaaki, Habu, Manabu, Takahashi, Osamu, Nishihara, Tatsuji, Tominaga, Kazuhiro, Takenaka, Shigeori

“…Telomerase is regarded as a good marker for cancer because it is unregulated in most tumor cells compared with normal cells. We evaluated telomerase activity…”
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Diagnosis of Periodontal Disease from Saliva Samples Using Fourier Transform Infrared Microscopy Coupled with Partial Least Squares Discriminant Analysis by FUJII, Satoshi, SATO, Shinobu, FUKUDA, Keisuke, OKINAGA, Toshinori, ARIYOSHI, Wataru, USUI, Michihiko, NAKASHIMA, Keisuke, NISHIHARA, Tatsuji, TAKENAKA, Shigeori

“…Diagnosis of periodontal disease by Fourier transform infrared (FT-IR) microscopic technique was achieved for saliva samples. Twenty-two saliva samples,…”
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Formation and Electrical Evaluation of a Single Metallized DNA Nanowire in a Nanochannel by Himuro, Takahiro, Sato, Shinobu, Takenaka, Shigeori, Yasuda, Takashi

“…A novel fabrication process was developed for a single silver nanowire using DNA metallization in a nanochannel, and the electrical properties of this nanowire…”
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Fluorescence Imaging of Extracellular Potassium Ion Using Potassium Sensing Oligonucleotide by Sato, Shinobu, Ohzawa, Shinsuke, Sota, Kojiro, Sakamoto, Naoto, Udo, Ayano, Sueda, Shinji, Matsuda, Tomoki, Nagai, Takeharu, Takenaka, Shigeori

“…Potassium-sensing oligonucleotide, PSO, a conjugate of a quadruplex structure-forming oligonucleotide with a peptide incorporating a Förster Resonance Energy…”
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Electrochemical DNA Detection Using Supramolecular Interactions by SATO, Shinobu, TAKENAKA, Shigeori

“…An electrochemical DNA detection format has been developed to allow simple and rapid assays with downsized instruments. Since naphthalene diimide derivatives…”
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The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis by Haraguchi, Kazuya, Yada, Naomi, Sato, Shinobu, Habu, Manabu, Hayakawa, Mana, Takahashi, Osamu, Sasaguri, Masaaki, Takenaka, Shigeori, Yoshioka, Izumi, Matsuo, Kou, Tominaga, Kazuhiro

“…Telomerase activity is present in most cancers and is tightly regulated by the expression of human telomerase reverse transcriptase (hTERT). Hypermethylation…”
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Screening for Oral Cancer Using Electrochemical Telomerase Assay by Hayakawa, Mana, Sato, Shinobu, Diala, Irmina, Kodama, Masaaki, Tomoeda-Mori, Kumiko, Haraguchi, Kazuya, Tominaga, Kazuhiro, Takenaka, Shigeori

“…Electrochemical telomerase assay (ECTA) developed by our group was evaluated in an oral cancer screening using exfoliated oral cells and tissues obtained from…”
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Electrochemical detection of aberrant methylated gene using naphthalene diimide derivative carrying four ferrocene moieties by Sato, Shinobu, Tsueda, Masato, Takenaka, Shigeori

“…Naphthalene diimide derivative, F4ND, carrying four ferrocene moieties was synthesized as a new hybridization indicator for electrochemical gene detection…”
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Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate by Ohtsuka, Keiichi, Sato, Shinobu, Sato, Yusuke, Sota, Kojiro, Ohzawa, Shinsuke, Matsuda, Tomoki, Takemoto, Kiwamu, Takamune, Nobutoki, Juskowiak, Bernard, Nagai, Takeharu, Takenaka, Shigeori

“…When a biotinylated FRET probe based on a peptide-thrombin binding aptamer conjugate was introduced together with streptavidin and biotinylated nuclear export…”
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Metallization of Double-Stranded DNA Triggered by Bound Galactose-Modified Naphthalene Diimide by Komizo, Kohei, Ikedo, Hideyuki, Sato, Shinobu, Takenaka, Shigeori

“…Naphthalene diimide (NDI) derivatives bearing galactose moieties through different spacers, NDI-DS1 and NDI-DS2, were synthesized by the click reaction of the…”
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