Search Results - "Sato, Misako"

Cytoglobin functions as a redox regulator of melanogenesis in normal epidermal melanocytes by Tanaka, Yo, Sato-Matsubara, Misako, Tsuruta, Daisuke, Tanaka, Hiroshi, Kadono, Chiho, Sugawara, Koji, Kawada, Norifumi, Wakamatsu, Kazumasa, Ito, Shosuke, Yoshizato, Katsutoshi

“…Epidermal melanocytes are continuously exposed to sunlight-induced reactive oxygen species (ROS) and oxidative stress generated during the synthesis of…”
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Improved Proteome and Phosphoproteome Analysis on a Cation Exchanger by a Combined Acid and Salt Gradient by Adachi, Jun, Hashiguchi, Kazunari, Nagano, Maiko, Sato, Misako, Sato, Ayako, Fukamizu, Kazuna, Ishihama, Yasushi, Tomonaga, Takeshi

“…Currently used elution methods for strong cation exchange (SCX) chromatography are based on two principles: salt and pH gradient. In this paper, we report the…”
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Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction by Sato, Misako, Muragaki, Yasuteru, Saika, Shizuya, Roberts, Anita B., Ooshima, Akira

“…Tubulointerstitial fibrosis is the final common result of a variety of progressive injuries leading to chronic renal failure. Transforming growth factor-β…”
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Hexa Histidine–Tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species by Dat, Ninh Quoc, Thuy, Le Thi Thanh, Hieu, Vu Ngoc, Hai, Hoang, Hoang, Dinh Viet, Thi Thanh Hai, Nguyen, Thuy, Tuong Thi Van, Komiya, Tohru, Rombouts, Krista, Dong, Minh Phuong, Hanh, Ngo Vinh, Hoang, Truong Huu, Sato‐Matsubara, Misako, Daikoku, Atsuko, Kadono, Chiho, Oikawa, Daisuke, Yoshizato, Katsutoshi, Tokunaga, Fuminori, Pinzani, Massimo, Kawada, Norifumi

“…Background and Aims Antifibrotic therapy remains an unmet medical need in human chronic liver disease. We report the antifibrotic properties of cytoglobin…”
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New player in tumor‐stromal interaction: Granulin as a novel therapeutic target for pancreatic ductal adenocarcinoma liver metastasis by Sato‐Matsubara, Misako, Kawada, Norifumi

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Cloaking the ACE2 receptor with salivary cationic proteins inhibits SARS-CoV-2 entry by Yoshizato, Katsutoshi, Taira, Toshio, Sato-Matsubara, Misako, Sekiguchi, Shizuko, Yabunaka, Yoriko, Kira, Yukimi, Ohashi, Tetsu, Daikoku, Atsuko, Ofusa, Ken, Kadono, Chiho, Oikawa, Daisuke, Matsubara, Tsutomu, Nakagama, Yu, Kido, Yasutoshi, Tokunaga, Fuminori, Ikeda, Kazuo, Kaneko, Akira, Kawada, Norifumi

“…Abstract Saliva contributes to the innate immune system, which suggests that it can prevent SARS-CoV-2 entry. We studied the ability of healthy salivary…”
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Association between HLA‐DQA1/DRB1 polymorphism and development of hepatocellular carcinoma during entecavir treatment by Kozuka, Ritsuzo, Enomoto, Masaru, Sato‐Matsubara, Misako, Yoshida, Kanako, Motoyama, Hiroyuki, Hagihara, Atsushi, Fujii, Hideki, Uchida‐Kobayashi, Sawako, Morikawa, Hiroyasu, Tamori, Akihiro, Kawada, Norifumi, Murakami, Yoshiki

“…Background and Aims It remains unclear whether there is an association between single‐nucleotide polymorphisms (SNPs) and development of hepatocellular…”
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Real-time motion analysis reveals cell directionality as an indicator of breast cancer progression by Weiger, Michael C, Vedham, Vidya, Stuelten, Christina H, Shou, Karen, Herrera, Mark, Sato, Misako, Losert, Wolfgang, Parent, Carole A

“…Cancer cells alter their migratory properties during tumor progression to invade surrounding tissues and metastasize to distant sites. However, it remains…”
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Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines by Kadota, Mitsutaka, Yang, Howard H, Gomez, Bianca, Sato, Misako, Clifford, Robert J, Meerzaman, Daoud, Dunn, Barbara K, Wakefield, Lalage M, Lee, Maxwell P

“…To gain insight into the role of genomic alterations in breast cancer progression, we conducted a comprehensive genetic characterization of a series of four…”
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Strategy for SRM-based Verification of Biomarker Candidates Discovered by iTRAQ Method in Limited Breast Cancer Tissue Samples by Muraoka, Satoshi, Kume, Hideaki, Watanabe, Shio, Adachi, Jun, Kuwano, Masayoshi, Sato, Misako, Kawasaki, Naoko, Kodera, Yoshio, Ishitobi, Makoto, Inaji, Hideo, Miyamoto, Yasuhide, Kato, Kikuya, Tomonaga, Takeshi

“…Since LC–MS-based quantitative proteomics has become increasingly applied to a wide range of biological applications over the past decade, numerous studies…”
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Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species by Hoang, Dinh Viet, Thuy, Le Thi Thanh, Hai, Hoang, Hieu, Vu Ngoc, Kimura, Kenjiro, Oikawa, Daisuke, Ikura, Yoshihiro, Dat, Ninh Quoc, Hoang, Truong Huu, Sato-Matsubara, Misako, Dong, Minh Phuong, Hanh, Ngo Vinh, Uchida-Kobayashi, Sawako, Tokunaga, Fuminori, Kubo, Shoji, Ohtani, Naoko, Yoshizato, Katsutoshi, Kawada, Norifumi

“…Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer…”
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Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model by Sato, Misako, Matsubara, Tsutomu, Adachi, Jun, Hashimoto, Yuuki, Fukamizu, Kazuna, Kishida, Marina, Yang, Yu-An, Wakefield, Lalage M, Tomonaga, Takeshi

“…Transforming growth factor-β (TGF-β) has a dual role in tumorigenesis, acting as either a tumor suppressor or as a pro-oncogenic factor in a context-dependent…”
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Trps1 regulates proliferation and apoptosis of chondrocytes through Stat3 signaling by Suemoto, Hiroki, Muragaki, Yasuteru, Nishioka, Katsuhiro, Sato, Misako, Ooshima, Akira, Itoh, Shunji, Hatamura, Ikuji, Ozaki, Michitaka, Braun, Attila, Gustafsson, Erika, Fässler, Reinhard

“…Mutations in the TRPS1 gene lead to the tricho-rhino-phalangeal syndrome, which is characterized by skeletal defects and abnormal hair development. The TRPS1…”
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TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury[S] by Matsubara, Tsutomu, Tanaka, Naoki, Sato, Misako, Kang, Dong Wook, Krausz, Kristopher W., Flanders, Kathleen C., Ikeda, Kazuo, Luecke, Hans, Wakefield, Lalage M., Gonzalez, Frank J.

“…Transforming growth factor-β (TGFβ) is activated as a result of liver injury, such as cholestasis. However, its influence on endogenous metabolism is not…”
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Anti-fibrotic treatments for chronic liver diseases: the present and the future by Odagiri, Naoshi, Matsubara, Tsutomu, Sato-Matsubara, Misako, Fujii, Hideki, Enomoto, Masaru, Kawada, Norifumi

“…Liver fibrosis reflects tissue scarring in the liver due to the accumulation of excessive extracellular matrix in response to chronically persistent liver…”
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Smad3 Signaling Is Required for Epithelial-Mesenchymal Transition of Lens Epithelium after Injury by Saika, Shizuya, Kono-Saika, Satoko, Ohnishi, Yoshitaka, Sato, Misako, Muragaki, Yasuteru, Ooshima, Akira, Flanders, Kathleen C., Yoo, Jiyun, Anzano, Mario, Liu, Chia-Yang, Kao, Winston W.–Y., Roberts, Anita B.

“…Lens epithelial cells undergo epithelial-mesenchymal transition (EMT) after injury as in cataract extraction, leading to fibrosis of the lens capsule. Fibrosis…”
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Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes by Okina, Yoshinori, Sato-Matsubara, Misako, Kido, Yasutoshi, Urushima, Hayato, Daikoku, Atsuko, Kadono, Chiho, Nakagama, Yu, Nitahara, Yuko, Hoang, Truong Huu, Thuy, Le Thi Thanh, Matsubara, Tsutomu, Ohtani, Naoko, Ikeda, Kazuo, Yoshizato, Katsutoshi, Kawada, Norifumi

“…Cell-cell interactions between hepatocytes (Hep) and other liver cells are key to maintaining liver homeostasis. Cytoglobin (CYGB), expressed exclusively by…”
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Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling by Sato-Matsubara, Misako, Matsubara, Tsutomu, Daikoku, Atsuko, Okina, Yoshinori, Longato, Lisa, Rombouts, Krista, Thuy, Le Thi Thanh, Adachi, Jun, Tomonaga, Takeshi, Ikeda, Kazuo, Yoshizato, Katsutoshi, Pinzani, Massimo, Kawada, Norifumi

“…Cytoglobin (CYGB) belongs to the mammalian globin family and is exclusively expressed in hepatic stellate cells (HSCs) in the liver. In addition to its…”
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Soluble Immune Checkpoint Protein CD27 Is a Novel Prognostic Biomarker of Hepatocellular Carcinoma Development in Hepatitis C Virus–Sustained Virological Response Patients by Dong, Minh Phuong, Thuy, Le Thi Thanh, Hoang, Dinh Viet, Hai, Hoang, Hoang, Truong Huu, Sato-Matsubara, Misako, Hieu, Vu Ngoc, Daikoku, Atsuko, Hanh, Ngo Vinh, Urushima, Hayato, Dat, Ninh Quoc, Uchida-Kobayashi, Sawako, Enomoto, Masaru, Ohtani, Naoko, Tamori, Akihiro, Kawada, Norifumi

“…Factors affecting the probability of hepatocellular carcinoma (HCC) development even after sustained virological response (SVR) following anti–hepatitis C…”
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Double-Blind Randomized Clinical Trial of the Effects of Ezetimibe on Postprandial Hyperlipidaemia and Hyperglycaemia by Kikuchi, Kaori, Nezu, Uru, Inazumi, Koji, Miyazaki, Takashi, Ono, Kanako, Orime, Kazuki, Shirakawa, Jun, Sato, Koichiro, Koike, Hirofumi, Wakasugi, Tadashi, Sato, Misako, Kawakami, Chihiro, Watanabe, Shinichiro, Yamakawa, Tadashi, Terauchi, Yasuo

“…Aim: Ezetimibe selectively blocks intestinal cholesterol absorption by inhibiting Niemann-Pick C1-like 1 (NPC1L1) and reducing LDL cholesterol (LDL-C). In…”
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