Search Results - "Sato, Atsuyasu"

SP-B and SP-C containing new synthetic surfactant for treatment of extremely immature lamb lung by Sato, Atsuyasu, Ikegami, Machiko

“…Although superiority of synthetic surfactant over animal-driven surfactant has been known, there is no synthetic surfactant commercially available at present…”
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Fraction of MHCII and EpCAM expression characterizes distal lung epithelial cells for alveolar type 2 cell isolation by Hasegawa, Koichi, Sato, Atsuyasu, Tanimura, Kazuya, Uemasu, Kiyoshi, Hamakawa, Yoko, Fuseya, Yoshinori, Sato, Susumu, Muro, Shigeo, Hirai, Toyohiro

“…Alveolar type 2 (AT2) cells play important roles in maintaining adult lung homeostasis. AT2 cells isolated from the lung have revealed the cell-specific…”
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Subtyping emphysematous COPD by respiratory volume change distributions on CT by Shima, Hiroshi, Tanabe, Naoya, Oguma, Akira, Shimizu, Kaoruko, Kaji, Shizuo, Terada, Kunihiko, Oguma, Tsuyoshi, Kubo, Takeshi, Suzuki, Masaru, Makita, Hironi, Sato, Atsuyasu, Nishimura, Masaharu, Sato, Susumu, Konno, Satoshi, Hirai, Toyohiro

“…There is considerable heterogeneity among patients with emphysematous chronic obstructive pulmonary disease (COPD). We hypothesised that in addition to…”
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Associations of fractional exhaled nitric oxide with airway dimension and mucus plugs on ultra-high-resolution computed tomography in former smokers and nonsmokers with asthma by Hayashi, Yusuke, Tanabe, Naoya, Matsumoto, Hisako, Shimizu, Kaoruko, Sakamoto, Ryo, Oguma, Tsuyoshi, Sunadome, Hironobu, Sato, Atsuyasu, Sato, Susumu, Hirai, Toyohiro

“…Associations of fractional exhaled nitric oxide (FeNO) with airway wall remodeling and mucus plugs remain to be explored in smokers and nonsmokers with asthma…”
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Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity by Tsao, Po-Nien, Matsuoka, Chisa, Wei, Shu-Chen, Sato, Atsuyasu, Sato, Susumu, Hasegawa, Koichi, Chen, Hung-kuan, Ling, Thai-Yen, Mori, Munemasa, Cardoso, Wellington V., Morimoto, Mitsuru

“…Abnormal enlargement of the alveolar spaces is a hallmark of conditions such as chronic obstructive pulmonary disease and bronchopulmonary dysplasia. Notch…”
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Associations of pulmonary and extrapulmonary computed tomographic manifestations with impaired physical activity in symptomatic patients with chronic obstructive pulmonary disease by Hamakawa, Yoko, Tanabe, Naoya, Shima, Hiroshi, Terada, Kunihiko, Shiraishi, Yusuke, Maetani, Tomoki, Kubo, Takeshi, Kozawa, Satoshi, Koizumi, Koji, Kanezaki, Masashi, Shimizu, Kaoruko, Oguma, Tsuyoshi, Sato, Atsuyasu, Sato, Susumu, Hirai, Toyohiro

“…In patients with chronic obstructive pulmonary disease (COPD), emphysema, airway disease, and extrapulmonary comorbidities may cause various symptoms and…”
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Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease by Uemasu, Kiyoshi, Tanabe, Naoya, Tanimura, Kazuya, Hasegawa, Koichi, Mizutani, Tatsushi, Hamakawa, Yoko, Sato, Susumu, Ogawa, Emiko, Thomas, Matthew J., Ikegami, Machiko, Muro, Shigeo, Hirai, Toyohiro, Sato, Atsuyasu

“…Epithelial dysfunction in the small airways may cause the development of emphysema in chronic obstructive pulmonary disease. C/EBPα (CCAAT/enhancer binding…”
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Direct evaluation of peripheral airways using ultra-high-resolution CT in chronic obstructive pulmonary disease by Tanabe, Naoya, Shima, Hiroshi, Sato, Susumu, Oguma, Tsuyoshi, Kubo, Takeshi, Kozawa, Satoshi, Koizumi, Koji, Sato, Atsuyasu, Togashi, Kaori, Hirai, Toyohiro

“…•A small airway <2 mm in diameter is a major pathological site in COPD.•Small airways <2 mm in diameter cannot be evaluated with conventional…”
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CCAAT/enhancer-binding protein-α suppresses lung tumor development in mice through the p38α MAP kinase pathway by Sato, Atsuyasu, Yamada, Norishige, Ogawa, Yuya, Ikegami, Machiko

“…The transcription factor CCAAT/enhancer-binding protein α (C/EBPα) is a basic leucine zipper transcription factor and is expressed in alveolar type II cells,…”
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Associations of airway tree to lung volume ratio on computed tomography with lung function and symptoms in chronic obstructive pulmonary disease by Tanabe, Naoya, Sato, Susumu, Oguma, Tsuyoshi, Shima, Hiroshi, Sato, Atsuyasu, Muro, Shigeo, Hirai, Toyohiro

“…Decreased airway lumen size and increased lung volume are major structural changes in chronic obstructive pulmonary disease (COPD). However, even though the…”
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Mucus plugging on computed tomography and the sputum microbiome in patients with asthma, chronic obstructive pulmonary disease, and asthma-COPD overlap by Tanabe, Naoya, Matsumoto, Hisako, Morimoto, Chie, Hayashi, Yusuke, Sakamoto, Ryo, Oguma, Tsuyoshi, Nagasaki, Tadao, Sunadome, Hironobu, Sato, Atsuyasu, Sato, Susumu, Ohashi, Kai, Tsukahara, Takamitsu, Hirai, Toyohiro

“…Despite clinical implications, the pathogenesis of mucus plugging in asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap (ACO)…”
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Fractal analysis of low attenuation clusters on computed tomography in chronic obstructive pulmonary disease by Tanabe, Naoya, Muro, Shigeo, Sato, Susumu, Oguma, Tsuyoshi, Sato, Atsuyasu, Hirai, Toyohiro

“…The fractal dimension characterizing the cumulative size distribution of low attenuation area (LAA) clusters, identified with a fixed threshold such as - 950…”
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Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size by Bridges, James P, Ludwig, Marie-Gabrielle, Mueller, Matthias, Kinzel, Bernd, Sato, Atsuyasu, Xu, Yan, Whitsett, Jeffrey A, Ikegami, Machiko

“…Pulmonary surfactant levels within the alveoli are tightly regulated to maintain lung volumes and promote efficient gas exchange across the air/blood barrier…”
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Lobar distribution of non-emphysematous gas trapping and lung hyperinflation in chronic obstructive pulmonary disease by Shima, Hiroshi, Tanabe, Naoya, Sato, Susumu, Oguma, Tsuyoshi, Kubo, Takeshi, Kozawa, Satoshi, Koizumi, Koji, Watanabe, Aya, Sato, Atsuyasu, Togashi, Kaori, Hirai, Toyohiro

“…Lung hyperinflation in chronic obstructive pulmonary disease (COPD) is closely associated with emphysema and non-emphysematous gas trapping, termed functional…”
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Protocol for cell-type-specific tissue reconstruction in the murine lung fibrogenic microenvironment by Hasegawa, Koichi, Miyata, Ryo, Menju, Toshi, Hirai, Toyohiro, Date, Hiroshi, Sato, Atsuyasu

“…Pulmonary fibrosis is a process characterized by epithelial injury and fibroblast activation. It is also well recognized as a predisposition to lung cancer…”
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Surfactant Protein-D Inhibits Lung Inflammation Caused by Ventilation in Premature Newborn Lambs by SATO, Atsuyasu, WHITSETT, Jeffrey A, SCHEULE, Ronald K, LKEGAMI, Machiko

“…Premature newborns frequently require manual ventilation for resuscitation during which lung injury occurs. Although surfactant protein (SP)-D regulates…”
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Influence of Asthma Onset on Airway Dimensions on Ultra–high-resolution Computed Tomography in Chronic Obstructive Pulmonary Disease by Tanabe, Naoya, Sato, Susumu, Oguma, Tsuyoshi, Shima, Hiroshi, Kubo, Takeshi, Kozawa, Satoshi, Koizumi, Koji, Sato, Atsuyasu, Togashi, Kaori, Matsumoto, Hisako, Hirai, Toyohiro

“…PURPOSE:Asthma onset before the age of 40 years is associated with distinct clinical manifestations in chronic obstructive pulmonary disease (COPD) patients,…”
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Physiological Impairments on Respiratory Oscillometry and Future Exacerbations in Chronic Obstructive Pulmonary Disease Patients without a History of Frequent Exacerbations by Zhang, Yi, Tanabe, Naoya, Shima, Hiroshi, Shiraisi, Yusuke, Oguma, Tsuyoshi, Sato, Atsuyasu, Muro, Shigeo, Sato, Susumu, Hirai, Toyohiro

“…Respiratory oscillometry allows measuring respiratory resistance and reactance during tidal breathing and may predict exacerbations in patients with chronic…”
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Complementary regional heterogeneity information from COPD patients obtained using oxygen-enhanced MRI and chest CT by Fuseya, Yoshinori, Muro, Shigeo, Sato, Susumu, Tanabe, Naoya, Sato, Atsuyasu, Tanimura, Kazuya, Hasegawa, Koichi, Uemasu, Kiyoshi, Kubo, Takeshi, Kido, Aki, Fujimoto, Koji, Fushimi, Yasutaka, Kusahara, Hiroshi, Sakashita, Naotaka, Ohno, Yoshiharu, Togashi, Kaori, Mishima, Michiaki, Hirai, Toyohiro

“…The heterogeneous distribution of emphysema is a key feature of chronic obstructive pulmonary disease (COPD) patients that typically is evaluated using…”
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Association between blood eosinophil count and small airway eosinophils in smokers with and without COPD by Maetani, Tomoki, Tanabe, Naoya, Sato, Atsuyasu, Shiraishi, Yusuke, Sakamoto, Ryo, Ogawa, Emiko, Sakai, Hiroaki, Matsumoto, Hisako, Sato, Susumu, Date, Hiroshi, Hirai, Toyohiro, Muro, Shigeo

“…Introduction Airway eosinophilic inflammation is a pathological feature in a subgroup of patients with COPD and in some smokers with a high COPD risk. Although…”
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