Search Results - "Satler, Carol"

Monitoring for Pulmonary Hypertension Following Pulmonary Embolism: The INFORM Study by Tapson, Victor F., MD, Platt, David, MD, Xia, Fang, PhD, Teal, Simon A., BSc, Orden, Margarita de la, MSc, Divers, Christine H., PhD, Satler, Carol A., MD, PhD, Joish, Vijay N., PhD, Channick, Richard N., MD

“…Abstract Background Pulmonary hypertension and chronic thromboembolic pulmonary hypertension may develop after a pulmonary embolism event. A…”
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Safety and efficacy of RT234 vardenafil inhalation powder on exercise parameters in pulmonary arterial hypertension: phase II, dose-escalation study design by Benza, Raymond L, Franco, Veronica, Aras, Mandar A, Spikes, Leslie, Grinnan, Daniel, Satler, Carol

“…Pulmonary arterial hypertension (PAH) is a progressive disease characterized by high mean pulmonary arterial pressure (≥ 20 mmHg) and remodeling of the…”
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Toward More Individualized Treatment of Pulmonary Arterial Hypertension: Investigation of Biomarkers for Nitric Oxide Deficiency by Klinger, James, MD, McMahon, Timothy, PhD, Dweik, Raed, MD, Platt, David, MD, O'Brien, Gerald, MD, Satler, Carol, PhD

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Measuring Outcomes in Patients With Pulmonary Arterial Hypertension (PAH) Not on Active Treatment (MOTION): A Study of the Effects of Riociguat on Patient-Reported Outcomes and an Exploration of Telemetric Technology in PAH by Mathai, Stephen, MD, Minai, Omar, MD, Sullivan, Sean, PhD, Lerner, Debra, PhD, Levine, Deborah, Platt, David, MD, O'Brien, Gerald, MD, Satler, Carol, PhD

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Two isoforms of the mouse Ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current by LONDON, B, TRUDEAU, M. C, NEWTON, K. P, BEYER, A. K, COPELAND, N. G, GILBERT, D. J, JENKINS, N. A, SATLER, C. A, ROBERTSON, G. A

“…HERG, the human ether-a-go-go-related gene, encodes a K(+)-selective channel with properties similar to the rapidly activating component of the delayed…”
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BAYESIAN APPROACH FOR ELEVATE IPF: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL TO EVALUATE EFFICACY, SAFETY, AND DOSE RESPONSE OF DEUPIRFENIDONE (LYT-100) IN IPF by ZHANG, YANQIONG, GRAHAM, CAMILLA, GOLOD, DAVID, SANTIPADRI, SARAH, JENSEN, THOMAS, WENDELBERGER, BARBARA, KROP, JULIE, SATLER, CAROL A

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Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge by Logothetis, D E, Movahedi, S, Satler, C, Lindpaintner, K, Nadal-Ginard, B

“…The S4 region of voltage-dependent ion channels is involved in the voltage-sensing mechanism of channel activation. Previous studies in fast inactivating…”
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Selonsertib in adults with pulmonary arterial hypertension (ARROW): a randomised, double-blind, placebo-controlled, phase 2 trial by Rosenkranz, Stephan, Feldman, Jeremy, McLaughlin, Vallerie V, Rischard, Franz, Lange, Tobias J, White, R James, Peacock, Andrew J, Gerhardt, Felix, Ebrahimi, Ramin, Brooks, Gabriel, Satler, Carol, Frantz, Robert P

“…Data obtained in human lung tissue and preclinical models suggest that oxidative stress and increased apoptosis signal-regulating kinase 1 (ASK1) activity…”
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Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations by Butler, Javed, Hamo, Carine E, Udelson, James E, O'Connor, Christopher, Sabbah, Hani N, Metra, Marco, Shah, Sanjiv J, Kitzman, Dalane W, Teerlink, John R, Bernstein, Harold S, Brooks, Gabriel, Depre, Christophe, DeSouza, Mary M, Dinh, Wilfried, Donovan, Mark, Frische-Danielson, Regina, Frost, Robert J, Garza, Dahlia, Gohring, Udo-Michael, Hellawell, Jennifer, Hsia, Judith, Ishihara, Shiro, Kay-Mugford, Patricia, Koglin, Joerg, Kozinn, Marc, Larson, Christopher J, Mayo, Martha, Gan, Li-Ming, Mugnier, Pierrre, Mushonga, Sekayi, Roessig, Lothar, Russo, Cesare, Salsali, Afshin, Satler, Carol, Shi, Victor, Ticho, Barry, van der Laan, Michael, Yancy, Clyde, Stockbridge, Norman, Gheorghiade, Mihai

“…The increasing burden and the continued suboptimal outcomes for patients with heart failure underlines the importance of continued research to develop novel…”
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Risk of Second Primary Malignancies (SPMs) Following Bortezomib (Btz)-Based Therapy: Analysis of Four Phase 3 Randomized Controlled Trials in Previously Untreated or Relapsed Multiple Myeloma (MM) by Miguel, Jesús F San, Richardson, Paul G., Orlowski, Robert Z., Goldschmidt, Hartmut, Corzo, Deyanira, Satler, Carol, Esseltine, Dixie-Lee, Neuwirth, Rachel, Ponsillo, Maria, Cakana, Andrew Z, King, Jay, Deraedt, William M, Desai, Avinash, Lutska, Yana, Gifkins, Dina, Liu, Kevin, Sonneveld, Pieter

“…Abstract 2933 MM patients have a significantly increased risk of developing certain SPMs subsequent to their initial diagnosis, including a 3.49-fold increased…”
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Multiple different missense mutations in the pore region of HERG in patients with long QT syndrome by SATLER, C. A, VESELY, M. R, DUGGAL, P, GINSBURG, G. S, BEGGS, A. H

“…Long QT syndrome (LQTS), is an inherited cardiac disorder in which ventricular tachyarrhythmias predispose affected individuals to syncope, seizures, and…”
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Missense mutation in the pore region of HERG causes familial long QT syndrome by BENSON, D. W, MACRAE, C. A, VESELY, M. R, WALSH, E. P, SEIDMAN, J. G, SEIDMAN, C. E, SATLER, C. A

“…Long QT syndrome (LQT) is an inherited cardiac disorder that results in syncope, seizures, and sudden death. In a family with LQT, we identified a novel…”
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Evidence of genetic heterogeneity in Romano-Ward long QT syndrome : analysis of 23 families by TOWBIN, J. A, HUA LI, TAGGART, R, LEHMANN, M. H, SCHWARTZ, P. J, SATLER, C. A, AYYAGARI, R, ROBINSON, J. L, MOSS, A, HEJTMANCIK, J. F

“…The Romano-Ward long-QT Syndrome (LQTS) is an autosomal dominant inherited trait characterized by prolonged QT interval on ECG, life-threatening arrhythmias,…”
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Novel missense mutation in the cyclic nucleotide-binding domain ofHERG causes long QT syndrome by Satler, Carol Ann, Walsh, Edward P., Vesely, Mark R., Plummer, Mark H., Ginsburg, Geoffrey S., Jacob, Howard J.

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Recent Advances in the Laboratory of Molecular and Cellular Cardiology by Breitbart, Roger E., London, Barry, Nguyen, Hanh T., Satler, Carol A.

“…This article highlights some of the research in cardiac molecular biology in progress in the Department of Cardiology at Children's Hospital. It provides a…”
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Recent advances in the Laboratory of Molecular and Cellular Cardiology by Breitbart, Roger E., London, Barry, Nguyen, Hanh T., Satler, Carol A.

“…This article highlights some of the research in cardiac molecular biology in progress in the Department of Cardiology at Children's Hospital. It provides a…”
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Two Isoforms of the Mouse Ether-a-go-go-Related Gene Coassemble to Form Channels With Properties Similar to the Rapidly Activating Component of the Cardiac Delayed Rectifier K sup + Current by London, Barry, Trudeau, Matthew C, Newton, Kimberly P, Beyer, Anita K, Copeland, Neal G, Gilbert, Debra J, Jenkins, Nancy A, Satler, Carol A, Robertson, Gail A

“…HERG, the human ether-a-go-go-related gene, encodes a K sub +-selective channel with properties similar to the rapidly activating component of the delayed…”
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Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome by Satler, Carol Ann, Walsh, Edward P., Vesely, Mark R., Plummer, Mark H., Ginsburg, Geoffrey S., Jacob, Howard J.

“…Autosomal‐dominant long QT syndrome (LQT) is an inherited disorder, predisposing affected individuals to sudden death from tachyarrhythmias. To identify the…”
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