Search Results - "Sather, S"

Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer by Linger, R M A, Cohen, R A, Cummings, C T, Sather, S, Migdall-Wilson, J, Middleton, D H G, Lu, X, Barón, A E, Franklin, W A, Merrick, D T, Jedlicka, P, DeRyckere, D, Heasley, L E, Graham, D K

“…Non-small cell lung cancer (NSCLC) is a prevalent and devastating disease that claims more lives than breast, prostate, colon and pancreatic cancers combined…”
Get full text

Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1 by Smith, A H, Jensen, K P, Li, J, Nunez, Y, Farrer, L A, Hakonarson, H, Cook-Sather, S D, Kranzler, H R, Gelernter, J

“…Opioids are very effective analgesics, but they are also highly addictive. Methadone is used to treat opioid dependence (OD), acting as a selective agonist at…”
Get full text

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia by Lee-Sherick, A B, Eisenman, K M, Sather, S, McGranahan, A, Armistead, P M, McGary, C S, Hunsucker, S A, Schlegel, J, Martinson, H, Cannon, C, Keating, A K, Earp, H S, Liang, X, DeRyckere, D, Graham, D K

“…Acute myeloid leukemia (AML) continues to be extremely difficult to treat successfully, and the unacceptably low overall survival rates mandate that we assess…”
Get full text

Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology by Rogers, A E J, Le, J P, Sather, S, Pernu, B M, Graham, D K, Pierce, A M, Keating, A K

“…Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive multimodality therapy. The…”
Get full text

The small‐molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis by Branchford, B. R., Stalker, T. J., Law, L., Acevedo, G., Sather, S., Brzezinski, C., Wilson, K. M., Minson, K., Lee‐Sherick, A. B., Davizon‐Castillo, P., Ng, C., Zhang, W., Neeves, K. B., Lentz, S. R., Wang, X., Frye, S. V., Shelton Earp, H., DeRyckere, D., Brass, L. F., Graham, D. K., Di Paola, J. A.

“…Essentials Signaling by Gas6 through Tyro3/Axl/Mer receptors is essential for stable platelet aggregation. UNC2025 is a small molecule inhibitor of the Mer…”
Get full text

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia by Lee-Sherick, A B, Eisenman, K M, Sather, S, McGranahan, A, Armistead, P M, McGary, C S, Hunsucker, S A, Schlegel, J, Martinson, H, Cannon, C, Keating, A K, Earp, H S, Liang, X, DeRyckere, D, Graham, D K

Get full text

Lymphoblastic leukemia lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase by KEATING, A. K, SALZBERG, D. B, PARK, J, CURRAN-EVERETT, D, MCGAVRAN, L, MELTESEN, L, GORE, L, JOHNSON, G. L, GRAHAM, D. K, SATHER, S, LIANG, X, NICKOLOFF, S, ANWAR, A, DERYCKERE, D, HILL, K, JOUNG, D, SAWCZYN, K. K

“…Mer (MerTK) is a receptor tyrosine kinase important in platelet aggregation, as well as macrophage cytokine secretion and clearance of apoptotic cells. Mer is…”
Get full text

Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia by Brandao, L N, Winges, A, Christoph, S, Sather, S, Migdall-Wilson, J, Schlegel, J, McGranahan, A, Gao, D, Liang, X, DeRyckere, D, Graham, D K

“…Pediatric leukemia survival rates have improved dramatically over the past decades. However, current treatment protocols are still largely ineffective in cases…”
Get full text

Lighted stylet tracheal intubation : A review by DAVIS, L, COOK-SATHER, S. D, SCHREINER, M. S

Get full text

A comparison of awake versus paralyzed tracheal intubation for infants with pyloric stenosis by COOK-SATHER, S. D, TULLOCH, H. V, CNAAN, A, NICOLSON, S. C, CUBINA, M. L, GALLAGHER, P. R, SCHREINER, M. S

“…This prospective, nonrandomized, observational study of 76 infants with pyloric stenosis was conducted at an academic children's hospital and compared awake…”
Get full text

Selective in vivo rescue by GroEL/ES of thermolabile folding intermediates to phage P22 structural proteins by Gordon, C L, Sather, S K, Casjens, S, King, J

“…The in vivo conformational substrates of the GroE chaperonins have been difficult to identify, in part because of limited information on in vivo polypeptide…”
Get full text

Lighted stylet intubation in the presence of cricoid pressure by Davis, L, Cook-Sather, S D

Get full text

A simple towel headrest for infants and children by Cook-Sather, S D

Get full text

General anesthesia versus deep sedation for children undergoing invasive procedures in oncologic clinic by S. Shah-Hosseini, Z. A. Fang, C. J. Bae, K. A. Harris, R. M. Chiavacci, R. Aplenc, A. F. Reilly, A. E. Kazak, S. D. Cook-Sather

“…Abstract Introduction Several successful general anesthetic and deep sedation techniques have been established for children under- going invasive oncologic…”
Get full text

Intracellular trapping of a cytoplasmic folding intermediate of the phage P22 tailspike using iodoacetamide by Sather, S K, King, J

“…Critical steps in polypeptide chain folding within the bacterial cytoplasm have been difficult to identify. Salmonella cells infected with…”
Get full text

157 EXPRESSION OF THE MER PROTO-ONCOGENE IN T CELL ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS IS ASSOCIATED WITH AN EARLY T CELL STAGE OF DIFFERENTIATION by Cao, J., Salzburg, D. B., Sather, S., Keating, A. K., Graham, D. K.

“…Tyrosine kinases play an important role in normal cellular growth and differentiation. Abnormal tyrosine kinase activity can result in cellular transformation…”
Get full text

Pulse oximetry probe adhesive disks: a potential for infant aspiration by Reddy, S P, Cook-Sather, S D

Get full text

Degradation of HMG-CoA reductase in vitro. Cleavage in the membrane domain by a membrane-bound cysteine protease by Moriyama, T, Sather, S K, McGee, T P, Simoni, R D

“…We have recently shown that the endoplasmic reticulum (ER) membrane protein, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, is cleaved in isolated…”
Get full text

A view from the other side of the bed by Sather, S A, Zwelling, E

“…A unique perspective on multiple pregnancy is shared through the writings of an expectant mother of triplets during the 19 weeks she spent on strict bed rest,…”
Get more information

A 5' spliced leader is added in trans to both alpha- and beta-tubulin transcripts in Trypanosoma brucei by Sather, S, Agabian, N

“…The approximately 15 α - and 15 β -tubulin genes of Trypanosoma brucei are arranged in a tandem array of alternating α - and β -tubulin genes. We have examined…”
Get full text