Search Results - "Sassoon, David A"

Identification and characterization of a non-satellite cell muscle resident progenitor during postnatal development by Gomes, Edgar R, Marazzi, Giovanna, Mitchell, Kathryn J, Cadot, Bruno, Parlakian, Ara, Sassoon, David A, Besson, Vanessa, Pannérec, Alice

“…In postnatal skeletal muscle, satellite cells are resident myogenic progenitors responsible for muscle growth and regeneration. A distinct population of…”
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Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development by Vallecillo-García, Pedro, Orgeur, Mickael, vom Hofe-Schneider, Sophie, Stumm, Jürgen, Kappert, Verena, Ibrahim, Daniel M., Börno, Stefan T., Hayashi, Shinichiro, Relaix, Frédéric, Hildebrandt, Katrin, Sengle, Gerhard, Koch, Manuel, Timmermann, Bernd, Marazzi, Giovanna, Sassoon, David A., Duprez, Delphine, Stricker, Sigmar

“…Fibro-adipogenic progenitors (FAPs) are an interstitial cell population in adult skeletal muscle that support muscle regeneration. During development,…”
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Paternally expressed gene 3 (Pw1/Peg3) promotes sexual dimorphism in metabolism and behavior by Tanaka, Karo, Besson, Vanessa, Rivagorda, Manon, Oury, Franck, Marazzi, Giovanna, Sassoon, David A

“…The paternally expressed gene 3 (Pw1/Peg3) is a mammalian-specific parentally imprinted gene expressed in stem/progenitor cells of the brain and endocrine…”
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The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal by Correra, Rosa Maria, Ollitrault, David, Valente, Mariana, Mazzola, Alessia, Adalsteinsson, Bjorn T., Ferguson-Smith, Anne C., Marazzi, Giovanna, Sassoon, David A.

“…Pw1/Peg3 is an imprinted gene expressed from the paternally inherited allele. Several imprinted genes, including Pw1/Peg3 , have been shown to regulate overall…”
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A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior by Denizot, Anne-Lyse, Besson, Vanessa, Correra, Rosa Maria, Mazzola, Alessia, Lopes, Izolina, Courbard, Jean-Remy, Marazzi, Giovanna, Sassoon, David A

“…Parental imprinting is a mammalian-specific form of epigenetic regulation in which one allele of a gene is silenced depending on its parental origin…”
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Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2 by Vandenberg, Alysia L, Sassoon, David A

“…Wnt signaling effectors direct the development and adult remodeling of the female reproductive tract (FRT); however, the role of non-canonical Wnt signaling…”
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PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations by Besson, Vanessa, Smeriglio, Piera, Wegener, Amélie, Relaix, Frédéric, Nait Oumesmar, Brahim, Sassoon, David A, Marazzi, Giovanna

“…A variety of markers are invaluable for identifying and purifying stem/progenitor cells. Here we report the generation of a murine reporter line driven by Pw1…”
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Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle by Formicola, Luigi, Pannérec, Alice, Correra, Rosa Maria, Gayraud-Morel, Barbara, Ollitrault, David, Besson, Vanessa, Tajbakhsh, Shahragim, Lachey, Jennifer, Seehra, Jasbir S, Marazzi, Giovanna, Sassoon, David A

“…Degenerative myopathies typically display a decline in satellite cells coupled with a replacement of muscle fibers by fat and fibrosis. During this…”
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Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury by Stumm, Jürgen, Vallecillo-García, Pedro, Vom Hofe-Schneider, Sophie, Ollitrault, David, Schrewe, Heinrich, Economides, Aris N., Marazzi, Giovanna, Sassoon, David A., Stricker, Sigmar

“…Fibro-adipogenic progenitors (FAPs) are resident mesenchymal progenitors in adult skeletal muscle that support muscle repair, but also give rise to fibrous and…”
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Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea by Dabdoub, Alain, Donohue, Maura J, Brennan, Angela, Wolf, Vladimir, Montcouquiol, Mireille, Sassoon, David A, Hseih, Jen-Chih, Rubin, Jeffrey S, Salinas, Patricia C, Kelley, Matthew W

“…In the mammalian cochlea, stereociliary bundles located on mechanosensory hair cells within the sensory epithelium are unidirectionally oriented. Development…”
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Defining skeletal muscle resident progenitors and their cell fate potentials by Pannérec, Alice, Formicola, Luigi, Besson, Vanessa, Marazzi, Giovanna, Sassoon, David A

“…The satellite cell is the major tissue-resident stem cell underlying muscle regeneration; however, multiple non-satellite myogenic progenitors as well as…”
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Fatty acid metabolism—the first trigger for cachexia? by Sassoon, David A

“…A recent study shows that skeletal muscle responds to tumor-secreted factors by undergoing a change in fatty acid metabolism, and that blocking this metabolic…”
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Effects of p21 deletion in mouse models of premature aging by Benson, Erica K., Zhao, Bo, Sassoon, David A., Lee, Sam W., Aaronson, Stuart A.

“…An approach to investigate the role of cellular senescence in organismal aging has been to abrogate signaling pathways known to induce cellular senescence and…”
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Induction of Homologue of Slimb Ubiquitin Ligase Receptor by Mitogen Signaling by Spiegelman, Vladimir S., Tang, Weigang, Chan, Andrew M., Igarashi, Makoto, Aaronson, Stuart A., Sassoon, David A., Katoh, Masaru, Slaga, Thomas J., Fuchs, Serge Y.

“…Homologue of Slimb (HOS) is the substrate-recognizing component of the SCFHOS-Roc1 E3 ubiquitin protein ligase. This ligase mediates ubiquitination of the…”
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The extraocular muscle stem cell niche is resistant to ageing and disease by Formicola, Luigi, Marazzi, Giovanna, Sassoon, David A

“…Specific muscles are spared in many degenerative myopathies. Most notably, the extraocular muscles (EOMs) do not show clinical signs of late stage myopathies…”
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Phosphotyrosine phosphatase inhibitor bisperoxovanadium endows myogenic cells with enhanced muscle stem cell functions via epigenetic modulation of Sca‐1 and Pw1 promoters by Smeriglio, Piera, Alonso‐Martin, Sonia, Masciarelli, Silvia, Madaro, Luca, Iosue, Ilaria, Marrocco, Valeria, Relaix, Frédéric, Fazi, Francesco, Marazzi, Giovanna, Sassoon, David A., Bouché, Marina

“…Understanding the regulation of the stem cell fate is fundamental for designing novel regenerative medicine strategies. Previous studies have suggested that…”
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PCBs Exert an Estrogenic Effect through Repression of the Wnt7a Signaling Pathway in the Female Reproductive Tract by Ma, Risheng, Sassoon, David A.

“…Polychlorinated biphenyls (PCBs) have been proposed to have a weak estrogenic activity and therefore pose a risk as potential environmental endocrine…”
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Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract by Miller, C, Sassoon, D A

“…The murine female reproductive tract differentiates along the anteroposterior axis during postnatal development. This process is marked by the emergence of…”
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A role for Wnt/β-catenin signaling in lens epithelial differentiation by Stump, Richard J.W, Ang, Sharyn, Chen, Yongjuan, von Bahr, Tatiana, Lovicu, Frank J, Pinson, Kathleen, de Iongh, Robbert U, Yamaguchi, Terry P, Sassoon, David A, McAvoy, John W

“…The differentiation of epithelial cells and fiber cells from the anterior and posterior compartments of the lens vesicle, respectively, give the mammalian lens…”
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Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis by Sassoon, David A, Miller, Cary, Degenhardt, Karl

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