Search Results - "Sassi Samia, Ben"
-
1
Interaction of Mitochondrial Polygenic Score and Lifestyle Factors in LRRK2 p.Gly2019Ser Parkinsonism
Published in Movement disorders (01-10-2023)“…A mitochondrial polygenic score (MGS) is composed of genes related to mitochondrial function and found to be associated with Parkinson's disease (PD) risk. To…”
Get full text
Journal Article -
2
Myoclonus status revealing COVID 19 infection
Published in Seizure (London, England) (01-01-2023)“…At the beginning of the coronavirus virus (COVID-19) pandemic, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) was thought to cause mainly…”
Get full text
Journal Article -
3
The Evolution of Genetic Variability at the LRRK2 Locus
Published in Genes (03-07-2024)“…Leucine-rich repeat kinase 2 ( ) c.6055G>A (p.G2019S) is a frequent cause of Parkinson's disease (PD), accounting for >30% of Tunisian Arab-Berber patients. is…”
Get full text
Journal Article -
4
The Genetic Architecture of Parkinson's Disease in the AfrAbia Population: Current State and Future Perspectives
Published in Journal of integrative neuroscience (19-08-2024)“…Over 80% of genetic studies in the Parkinson's disease (PD) field have been conducted on individuals of European descent. There is a social and scientific…”
Get full text
Journal Article -
5
Increased T-bet/GATA-3 and ROR-γt /Foxp3 Ratios in Cerebrospinal Fluid as Potential Criteria for Definite Neuro-Behçet’s Disease
Published in Journal of clinical medicine (29-07-2022)“…When the central nervous system (CNS) is the primary affected site in an initial attack of Behçet’s disease (BD), the differential diagnosis is particularly…”
Get full text
Journal Article -
6
LRRK2 Gly2019Ser penetrance in Arab–Berber patients from Tunisia: a case-control genetic study
Published in Lancet neurology (01-07-2008)“…Summary Background Several genes have been implicated in the pathogenesis of Parkinson's disease (PD). The aim of this study was to define the clinical…”
Get full text
Journal Article -
7
Challenges of Parkinson's disease GWASs in African people
Published in Lancet neurology (01-11-2023)“…The variant named rs3115534-G, which is in the non-coding region of GBA1 (the gene encoding the lysosomal enzyme glucocerebrosidase), is reported as a new…”
Get full text
Journal Article -
8
B Cells Specific CpG Induces High IL-10 and IL-6 Expression In Vitro in Neuro-Behçet's Disease
Published in Cells (Basel, Switzerland) (12-04-2022)“…Remitting-RelapsingMultiple Sclerosis (RRMS) and Neuro-Behçet Disease (NBD) are two chronic neuroinflammatory disorders leading to neurological damage. Herein,…”
Get full text
Journal Article -
9
A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's disease
Published in Journal of neurology, neurosurgery and psychiatry (01-04-2010)“…Genetic classification of Parkinson's disease (PD) subtypes may become the preferred diagnostic tool for neurologists. Herein we compare clinical features from…”
Get full text
Journal Article -
10
Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families
Published in Movement disorders (01-01-2007)“…Mutations in the leucine‐rich repeat kinase‐2 gene (LRRK2) are responsible for some forms of familial as well as sporadic Parkinson's disease (PD). The purpose…”
Get full text
Journal Article -
11
Genetic Modifiers of LRRK2 Parkinson's Disease: A Replication Study in Arab‐Berbers
Published in Movement disorders (01-04-2024)Get full text
Journal Article -
12
Myasthenia gravis and COVID‐19: A case series and comparison with literature
Published in Acta neurologica Scandinavica (01-09-2021)“…Objective To describe presenting symptoms, clinical outcomes, and therapeutic management of concurrent Coronavirus disease 2019 (COVID‐19) infections in…”
Get full text
Journal Article -
13
Comprehensive sequencing of the LRRK2 gene in patients with familial Parkinson's disease from North Africa
Published in Movement disorders (15-10-2010)“…The LRRK2 gene is a key player in Parkinson's disease (PD), however prevalence and pathogenicity of LRRK2 variants remain to be investigated in ethnically…”
Get full text
Journal Article -
14
Diffuse cerebral edema with leukoencephalopathy revealing systemic lupus erythematosus: A case report and review of literature
Published in Lupus (01-11-2023)“…Background: Systemic lupus erythematosus (SLE) is a common autoimmune disease with various symptoms involving multiple organs. Neuropsychological…”
Get full text
Journal Article -
15
Letter to editor response: Why myoclonus is linked to COVID19 infection, not to anti-COVID 19 vaccine
Published in Seizure (London, England) (01-03-2023)Get full text
Journal Article -
16
The AfrAbia+plus Parkinson's Disease Genomic Consortium
Published in Lancet neurology (01-02-2024)Get full text
Journal Article -
17
RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses
Published in Lancet neurology (01-06-2024)“…Parkinson's disease is a progressive neurodegenerative disorder with multifactorial causes, among which genetic risk factors play a part. The RAB GTPases are…”
Get full text
Journal Article -
18
Availability of Therapies and Services for Parkinson's Disease in Africa: A Continent‐Wide Survey
Published in Movement disorders (01-10-2021)“…Background The growing burden of Parkinson's disease (PD) in Africa necessitates the identification of available therapies and services to improve patient…”
Get full text
Journal Article -
19
Disability progression in multiple sclerosis: a Tunisian prospective cohort study
Published in Neurological sciences (01-05-2018)“…Data regarding multiple sclerosis (MS) course in North Africans are scarce and mainly retrospective. To prospectively assess disability progression of multiple…”
Get full text
Journal Article -
20
Motor phenotype of LRRK2-associated Parkinson's disease: A tunisian longitudinal study
Published in Movement disorders (01-02-2015)“…Mutations in the leucine‐rich repeat kinase 2 gene (LRRK2) were found to be a significant cause of late‐onset autosomal dominant forms of Parkinson's disease…”
Get full text
Journal Article