Search Results - "Sasseville, V."

Improvement of microwave emissivity parameterization of frozen Arctic soils using roughness measurements derived from photogrammetry by Meloche, J., Royer, A., Langlois, A., Rutter, N., Sasseville, V.

“…Soil emissivity of Arctic regions is a key parameter for assessing surface properties from microwave brightness temperature (Tb) measurements. Particularly in…”
Get full text

Safety Biomarkers in Preclinical Development: Translational Potential by Sasseville, V. G., Mansfield, K. G., Brees, D. J.

“…The identification, application, and qualification of safety biomarkers are becoming increasingly critical to successful drug discovery and development as…”
Get full text

Molecular Localization Techniques in the Diagnosis and Characterization of Nonhuman Primate Infectious Diseases by Mansfield, K. G., Sasseville, V. G., Westmoreland, S. V.

“…Molecular localization techniques remain important diagnostic and research tools for the pathologist evaluating nonhuman primate tissues. In situ hybridization…”
Get full text

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages by Stevenson, M, Swingler, S, Mann, A, Jacqué, J.-M, Brichacek, B, Sasseville, V.G, Williams, K, Lackner, A.A, Janoff, E.N, Wang, R, Fisher, D

“…Infection of macrophage lineage cells is a feature of primate lentivirus replication, and several properties of primate lentiviruses seem to have evolved to…”
Get full text

Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis by Westmoreland, SV, Rottman, JB, Williams, KC, Lackner, AA, Sasseville, VG

“…Although the mechanisms of human immunodeficiency virus (HIV) neuroinvasion, neuronal injury, and subsequent development of HIV-1-associated AIDS dementia…”
Get full text

Study on the Infectivity of Equine Herpesvirus 9 (EHV-9) by Different Routes of Inoculation in Hamsters by El-Habashi, N., Murakami, M., El-Nahass, E., Hibi, D., Sakai, H., Fukushi, H., Sasseville, V., Yanai, T.

“…The infectivity and pathology of equine herpesvirus 9 (EHV-9), a new neurotropic equine herpesvirus isolated from gazelles, was studied in hamsters…”
Get full text

A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus by Desrosiers, R C, Sasseville, V G, Czajak, S C, Zhang, X, Mansfield, K G, Kaur, A, Johnson, R P, Lackner, A A, Jung, J U

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Transcriptional Profiling of Liver and Effect of Glucocorticoids in a Rat Adjuvant-Induced Arthritis Model by Song, Y. L., Foster, W. R., Shuster, D. J., Nadler, S. G., Salter-Cid, L., Sasseville, V. G.

“…Glucocorticoids (GCs), despite having many undesirable side effects, remain effective for the treatment of many inflammatory diseases and are commonly used as…”
Get full text

Meeting Report: Spontaneous Lesions and Diseases in Wild, Captive-Bred, and Zoo-Housed Nonhuman Primates and in Nonhuman Primate Species Used in Drug Safety Studies by Sasseville, V. G., Mansfield, K. G., Mankowski, J. L., Tremblay, C., Terio, K. A., Mätz-Rensing, K., Gruber-Dujardin, E., Delaney, M. A., Schmidt, L. D., Liu, D., Markovits, J. E., Owston, M., Harbison, C., Shanmukhappa, S., Miller, A. D., Kaliyaperumal, S., Assaf, B. T., Kattenhorn, L., Macri, S. Cummings, Simmons, H. A., Baldessari, A., Sharma, P., Courtney, C., Bradley, A., Cline, J. M., Reindel, J. F., Hutto, D. L., Montali, R. J., Lowenstine, L. J.

“…The combination of loss of habitat, human population encroachment, and increased demand of select nonhuman primates for biomedical research has significantly…”
Get full text

Meeting Report: Emerging Respiratory Viral Infections and Nonhuman Primate Case Reports by Sasseville, V. G., Mankowski, J. L., Baldessari, A., Harbison, C., Laing, S., Kaliyaperumal, S., Mätz-Rensing, K., Miller, A. D., Schmidt, L. D., Kaplan-Kees, J., Dick, E. J., Reader, J. R., Liu, D., Crawford, L. K., Lane, J. H., Corner, S. M., Pardo, I. D., Evans, M. G., Murnane, R., Terio, K. A.

“…A workshop on Emerging Respiratory Viral Infections and Spontaneous Diseases in nonhuman primates was sponsored by the concurrent Annual Meetings of the…”
Get full text

Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis by Sasseville, VG, Smith, MM, Mackay, CR, Pauley, DR, Mansfield, KG, Ringler, DJ, Lackner, AA

“…The pathogenesis of neurological dysfunction associated with human immunodeficiency (HIV)-1 infection is uncertain. However, the presence of macrophage…”
Get full text

Control of Viremia in Simian Immunodeficiency Virus Infection by CD8$^+$ Lymphocytes by Schmitz, Jörn E., Kuroda, Marcelo J., Santra, Sampa, Sasseville, Vito G., Simon, Meredith A., Lifton, Michelle A., Racz, Paul, Tenner-Racz, Klara, Dalesandro, Margaret, Scallon, Bernhard J., Ghrayeb, John, Forman, Meryl A., Montefiori, David C., Rieber, E. Peter, Letvin, Norman L., Reimann, Keith A.

“…Clinical evidence suggests that cellular immunity is involved in controlling human immunodeficiency virus-1 (HIV-1) replication. An animal model of acquired…”
Get full text

Impact of infections and normal flora in nonhuman primates on drug development by Sasseville, V.G, Diters, R.W

“…Preclinical safety studies that are required for the marketing approval of a pharmaceutical include single and repeat dose studies in rodent and nonrodent…”
Get full text

Testing paradigm for prediction of development-limiting barriers and human drug toxicity by Sasseville, V.G., Lane, J.H., Kadambi, V.J., Bouchard, P., Lee, F.W., Balani, S.K., Miwa, G.T., Smith, P.F., Alden, C.L.

“…The financial investment grows exponentially as a new chemical entity advances through each stage of discovery and development. The opportunity exists for the…”
Get full text

Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus by Sasseville, VG, Newman, WA, Lackner, AA, Smith, MO, Lausen, NC, Beall, D, Ringler, DJ

“…AIDS encephalitis is a common sequela to HIV-1 infection in humans and simian immunodeficiency virus (SIVmac) infection in macaques. Although…”
Get full text

Atrioventricular Valvular Angiectasis in Sprague-Dawley Rats by Fang, H, Howroyd, P.C, Fletcher, A.M, Diters, R.W, Woicke, J, Sasseville, V.G, Bregman, C.L, Freebern, W.J, Durham, S.K, Mense, M.G

“…Subendothelial heart valve angiectasis has been reported in cows, dogs, pigs, rats, mice, and in human fetuses and newborns. We observed a high incidence (62…”
Get full text

Monocyte adhesion to endothelium in simian immunodeficiency virus- induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/alpha 4 beta 1 integrin interactions by Sasseville, VG, Newman, W, Brodie, SJ, Hesterberg, P, Pauley, D, Ringler, DJ

“…Because the mechanisms associated with recruitment of monocytes to brain in AIDS encephalitis are unknown, we used tissues from rhesus monkeys infected with…”
Get full text

Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain by Nottet, HS, Persidsky, Y, Sasseville, VG, Nukuna, AN, Bock, P, Zhai, QH, Sharer, LR, McComb, RD, Swindells, S, Soderland, C, Gendelman, HE

“…HIV-1 penetration of the brain is a pivotal event in the neuropathogenesis of AIDS-associated dementia. The establishment of productive viral replication or…”
Get full text

Identification of a nef allele that causes lymphocyte activation and acute disease in Macaque monkeys by Du, Zhenjian, Lang, Sabine M., Sasseville, Vito G., Lackner, Andrew A., Ilyinskii, Petr O., Daniel, Muthiah D., Jung, Jae U., Desrosiers, Ronald C.

“…Residues 17 and 18 In nef of SIVmac239 were changed from RQ to YE to create a translated sequence of SRP-SGDLYERLLRARGETYGRLLGEVEDGYSOSP from residues 10–43…”
Get full text

Enhanced Expression of Proinflammatory Cytokines in the Central Nervous System Is Associated with Neuroinvasion by Simian Immunodeficiency Virus and the Development of Encephalitis by Orandle, Marlene S, MacLean, Andrew G, Sasseville, Vito G, Alvarez, Xavier, Lackner, Andrew A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text