Search Results - "Sassani, André B"
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Expression of Fas Ligand in Arteries of Hypercholesterolemic Rabbits Accelerates Atherosclerotic Lesion Formation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-02-2000)“…ABSTRACTFas ligand (FasL) is expressed by cells of the arterial wall and is present in human atherosclerotic lesions. However, the role of FasL in modifying…”
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Second-Generation Adenoviral Vectors Do Not Prevent Rapid Loss of Transgene Expression and Vector DNA From the Arterial Wall
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2000)“…The utility of adenoviral vectors for arterial gene transfer is limited by the brevity of their expression and by inflammatory host responses. As a step toward…”
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Germline Incorporation of a Replication-Defective Adenoviral Vector in Mice Does Not Alter Immune Responses to Adenoviral Vectors
Published in Molecular therapy (01-11-2000)“…The utility of adenoviral vectors is limited by immune responses to adenoviral antigens. We sought to develop immune-competent mice in which the immune…”
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Adventitial delivery minimizes the proinflammatory effects of adenoviral vectors
Published in Journal of vascular surgery (01-03-1999)“…Purpose: Adenovirus-mediated arterial gene transfer is a promising tool in the study of vascular biology and the development of vascular gene therapy. However,…”
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