Search Results - "Sass, Thea"
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An Exploratory Study Provides Insights into MMP9 and Aβ Levels in the Vitreous and Blood across Different Ages and in a Subset of AMD Patients
Published in International journal of molecular sciences (23-11-2022)“…Matrix metalloproteinase-9 (MMP9) and total amyloid-beta (Aβ) are prospective biomarkers of ocular ageing and retinopathy. These were quantified by ELISA in…”
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SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Published in Nature microbiology (01-08-2022)“…Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly…”
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COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study
Published in Scientific reports (28-06-2022)“…The Delta (B.1.617.2) variant was the predominant UK circulating SARS-CoV-2 strain between May and December 2021. How Delta infection compares with previous…”
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SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2
Published in BMC infectious diseases (27-07-2022)“…Since the emergence of SARS-CoV-2, evolutionary pressure has driven large increases in the transmissibility of the virus. However, with increasing levels of…”
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Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning
Published in Scientific reports (19-07-2022)“…Whole genome sequencing of SARS-CoV-2 has occurred at an unprecedented scale, and can be exploited for characterising outbreak risks at the fine-scale needed…”
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Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes
Published in The Journal of hospital infection (01-05-2023)“…The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes…”
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Descriptive comparison of admission characteristics between pandemic waves and multivariable analysis of the association of the Alpha variant (B.1.1.7 lineage) of SARS-CoV-2 with disease severity in inner London
Published in BMJ open (08-02-2022)“…BackgroundThe Alpha variant (B.1.1.7 lineage) of SARS-CoV-2 emerged and became the dominant circulating variant in the UK in late 2020. Current literature is…”
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SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study
Published in BMJ open respiratory research (01-09-2021)“…BackgroundSARS-CoV-2 lineage B.1.1.7 has been associated with an increased rate of transmission and disease severity among subjects testing positive in the…”
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Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Published in Nature microbiology (01-10-2022)Get full text
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Developing an intervention to optimise the outcome of cardiac surgery in people with diabetes: the OCTOPuS pilot study
Published in Pilot and feasibility studies (17-08-2021)“…Background Cardiothoracic surgical outcomes are poorer in people with diabetes compared with those without diabetes. There are two important uncertainties in…”
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