Search Results - "Saso, Luciano"

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases by Singh, Anju, Kukreti, Ritushree, Saso, Luciano, Kukreti, Shrikant

“…Oxidative stress is proposed as a regulatory element in ageing and various neurological disorders. The excess of oxidants causes a reduction of antioxidants,…”
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Natural Sources, Pharmacokinetics, Biological Activities and Health Benefits of Hydroxycinnamic Acids and Their Metabolites by Sova, Matej, Saso, Luciano

“…Hydroxycinnamic acids (HCAs) are important natural phenolic compounds present in high concentrations in fruits, vegetables, cereals, coffee, tea and wine. Many…”
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An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation by Saha, Sarmistha, Buttari, Brigitta, Panieri, Emiliano, Profumo, Elisabetta, Saso, Luciano

“…Inflammation is a key driver in many pathological conditions such as allergy, cancer, Alzheimer's disease, and many others, and the current state of available…”
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Mechanistic Insight into Oxidative Stress-Triggered Signaling Pathways and Type 2 Diabetes by Singh, Anju, Kukreti, Ritushree, Saso, Luciano, Kukreti, Shrikant

“…Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the biochemical processes leading to elevated production of reactive oxygen…”
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Potential Applications of NRF2 Inhibitors in Cancer Therapy by Panieri, Emiliano, Saso, Luciano

“…The NRF2/KEAP1 pathway represents one of the most important cell defense mechanisms against exogenous or endogenous stressors. Indeed, by increasing the…”
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HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers by Moosavi, Fatemeh, Giovannetti, Elisa, Saso, Luciano, Firuzi, Omidreza

“…Cancer is a major cause of death worldwide. MET tyrosine kinase receptor [MET, c-MET, hepatocyte growth factor (HGF) receptor] pathway activation is associated…”
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Kaempferol as a Dietary Anti-Inflammatory Agent: Current Therapeutic Standing by Alam, Waqas, Khan, Haroon, Shah, Muhammad Ajmal, Cauli, Omar, Saso, Luciano

“…Inflammation is a physiological response to different pathological, cellular or vascular damages due to physical, chemical or mechanical trauma. It is…”
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Advances in research of Schiff-base metal complexes as potent antioxidants by Kostova, Irena, Saso, Luciano

“…The search for metal-derived antioxidants has received much attention and effort in order to identify the compounds having high capacity in scavenging free…”
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A Perspective on Nrf2 Signaling Pathway for Neuroinflammation: A Potential Therapeutic Target in Alzheimer's and Parkinson's Diseases by Saha, Sarmistha, Buttari, Brigitta, Profumo, Elisabetta, Tucci, Paolo, Saso, Luciano

“…Neuroinflammation plays a pivotal role in Alzheimer's disease (AD) and Parkinson's disease (PD), the leading causes of dementia. These neurological disorders…”
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Modulation of neurotrophic signaling pathways by polyphenols by Moosavi, Fatemeh, Hosseini, Razieh, Saso, Luciano, Firuzi, Omidreza

“…Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of…”
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Detection of Reactive Oxygen and Nitrogen Species by Electron Paramagnetic Resonance (EPR) Technique by Suzen, Sibel, Gurer-Orhan, Hande, Saso, Luciano

“…During the last decade there has been growing interest in physical-chemical oxidation processes and the behavior of free radicals in living systems. Radicals…”
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Pharmacological Modulation of Oxidative Stress by Saha, Sarmistha, Saso, Luciano

“…An imbalance between the formation of reactive oxygen species (ROS) and the reaction of antioxidant proteins is referred to as oxidative stress [...]…”
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PFAS Molecules: A Major Concern for the Human Health and the Environment by Panieri, Emiliano, Baralic, Katarina, Djukic-Cosic, Danijela, Buha Djordjevic, Aleksandra, Saso, Luciano

“…Per- and polyfluoroalkyl substances (PFAS) are a group of over 4700 heterogeneous compounds with amphipathic properties and exceptional stability to chemical…”
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Pharmacological applications of antioxidants: lights and shadows by Saso, Luciano, Firuzi, Omidreza

“…Oxidative stress is linked with many pathologies ranging from cancer to neurodegenerative disorders and antioxidants have presumably therapeutic value in such…”
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Oxidative Stress: Role and Response of Short Guanine Tracts at Genomic Locations by Singh, Anju, Kukreti, Ritushree, Saso, Luciano, Kukreti, Shrikant

“…Over the decades, oxidative stress has emerged as a major concern to biological researchers. It is involved in the pathogenesis of various lifestyle-related…”
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Controversy about pharmacological modulation of Nrf2 for cancer therapy by Milkovic, Lidija, Zarkovic, Neven, Saso, Luciano

“…Conventional anticancer therapies such as radiotherapy and chemotherapies are associated with oxidative stress generating reactive oxygen species (ROS) and…”
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The Nrf2 Pathway in Ischemic Stroke: A Review by Farina, Marcelo, Vieira, Leonardo Eugênio, Buttari, Brigitta, Profumo, Elisabetta, Saso, Luciano

“…Ischemic stroke, characterized by the sudden loss of blood flow in specific area(s) of the brain, is the leading cause of permanent disability and is among the…”
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Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs by Telkoparan-Akillilar, Pelin, Suzen, Sibel, Saso, Luciano

“…Oxidative stress (OS) is associated with many diseases ranging from cancer to neurodegenerative disorders. Nuclear factor-erythroid 2 p45-related factor 2…”
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Antioxidant Activity of Coumarins and Their Metal Complexes by Todorov, Lozan, Saso, Luciano, Kostova, Irena

“…Ubiquitously present in plant life, coumarins, as a class of phenolic compounds, have multiple applications-in everyday life, in organic synthesis, in medicine…”
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Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease by Ganguly, Gargi, Chakrabarti, Sasanka, Chatterjee, Uttara, Saso, Luciano

“…Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases of the elderly people that have devastating effects in terms of morbidity…”
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