Search Results - "Sasmal, Dinakar"
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Pharmacological evaluation of glutamate transporter 1 (GLT-1) mediated neuroprotection following cerebral ischemia/reperfusion injury
Published in European journal of pharmacology (25-07-2010)“…Recently glutamate transporters have emerged as a potential therapeutic target in a wide range of acute and chronic neurological disorders, owing to their…”
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2
Additional acetyl cholinesterase inhibitory property of diaryl pyrazoline derivatives
Published in Bioorganic & medicinal chemistry letters (01-02-2013)“…MAO-B and AChE are the two validated targets for Alzheimer’s disease. In pursuit of a single molecule hitting both the targets, we explored a set of previously…”
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3
Mechanism of deltamethrin induced thymic and splenic toxicity in mice and its protection by piperine and curcumin: in vivo study
Published in Drug and chemical toxicology (New York, N.Y. 1978) (02-01-2018)“…Deltamethrin (DLM) is a well-known pyrethroid insecticide which is widely used in the agriculture and home pest control due to restriction on the sale of…”
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4
Modulations of brain amines and dopaminergic behavior by a novel, reversible and selective MAO-B inhibitor
Published in Brain research (27-08-2012)“…Abstract Monoamine oxidase (MAO) B is a validated target for many neurodegenerative diseases. Recently we have reported a few pyrazolines as reversible and…”
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5
Development of a new in ovo model for the assessment of nephrotoxicity and its comparison with an existing in vivo model
Published in Current science (Bangalore) (10-03-2017)“…In this study, the chick embryo model has been used as an alternative to the mammalian model for assessing nephrotoxicity. Resemblance of the chick embryo to…”
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Mechanism of immunoprotective effects of curcumin in DLM-induced thymic apoptosis and altered immune function: an in silico and in vitro study
Published in Immunopharmacology and immunotoxicology (02-11-2015)“…Curcumin, a main component of Curcuma Longa Linn, is a plant polyphenol used as an immune-enhancer in the Indian system of traditional medicine. However, its…”
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7
Neuroprotection by rosiglitazone in transient focal cerebral ischemia might not be mediated by glutamate transporter-1
Published in Journal of neuroscience research (01-11-2011)“…Glutamate transport represents a key mechanism for maintaining low level of glutamate in the extracellular milieu to restrict the excitotoxic action of…”
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8
Antioxidant and DNA damage protective properties of anthocyanin-rich extracts from Hibiscus and Ocimum: a comparative study
Published in Natural product research (01-01-2014)“…Anthocyanin extracts (AEs) from Ocimum tenuiflorum (leaf), Hibiscus rosa-sinensis (petal) and Hibiscus sabdariffa (calyx) were investigated and compared for in…”
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9
An insight into deltamethrin induced apoptotic calcium, p53 and oxidative stress signalling pathways
Published in Toxicology and environmental health sciences (01-03-2015)“…Deltamethrin (DLM), a type 2 synthetic pyrethroid insecticide, is widely used in home and agricultural pest control. Humans are exposed to DLM by various modes…”
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10
Deltamethrin, a pyrethroid insecticide, could be a promising candidate as an anticancer agent
Published in Medical hypotheses (01-08-2015)“…Abstract Cancer is the one of the leading causes of death, whose incidences is increasing day by day. Various types of anticancer agents are used for its…”
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11
Anti-inflammatory and antinociceptive activity of arbortristoside-A
Published in Journal of ethnopharmacology (28-02-2008)“…Nyctanthes arbortristis Linn is a well-documented plant. It is evident from literature and previous investigations that Nyctanthes arbortristis possesses…”
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12
Evaluation of in silico, in vitro α-amylase inhibition potential and antidiabetic activity of Pterospermum acerifolium bark
Published in Pharmaceutical biology (01-02-2014)“…Pterospermum acerifolium (L.) Willd (Sterculiaceae) has been traditionally used in the treatment of diabetes mellitus but no scientific data has been published…”
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13
Antidiabetic Activity of Pterospermum acerifolium Flowers and Glucose Uptake Potential of Bioactive Fraction in L6 Muscle Cell Lines with Its HPLC Fingerprint
Published in BioMed research international (2014)“…The present study was designed to estimate the detailed antidiabetic activity of Pterospermum acerifolium (L.) Willd flowers. In vitro alpha amylase inhibition…”
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14
Evaluation of immunomodulatory activity of Glycyrhiza glabra L roots in combination with zing
Published in Asian Pacific journal of tropical biomedicine (01-01-2012)“…To determine the immunomodulatory properties of roots of Glycyrrhiza glabra (G. glabra) L. (Liquorice), and also to check whether significant potentiation in…”
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15
Aqueous extract of Boerhaavia diffusa root ameliorates ethylene glycol-induced hyperoxaluric oxidative stress and renal injury in rat kidney
Published in Pharmaceutical biology (01-12-2011)“…Boerhaavia diffusa Linn. (Nyctaginaceae) is widely used in traditional Indian medicines against renal afflictions including calcium oxalate (CaOx) urolithiasis…”
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Evaluation of antiarthritic and immunomodulatory activity of Barleria lupulina
Published in Asian Pacific journal of tropical biomedicine (2012)“…Barleria lupulina Lindl (Acanthaceae) (B. lupulina) has been traditionally used in the treatment of rheumatoid arthritis but, no scientific data has been…”
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17
Rheological Characterization and Drug Release Studies of Gum Exudates of Terminalia catappa Linn
Published in AAPS PharmSciTech (2008)“…The present study was undertaken to evaluate the gum exudates of Terminalia catappa Linn. (TC gum) as a release retarding excipient in oral controlled drug…”
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18
Stability-indicating validation of acitretin and isoacitretin in human plasma by LC-ESI-MS/MS bioanalytical method and its application to pharmacokinetic analysis
Published in Biomedical chromatography (01-06-2011)“…LC‐ ESI‐ MS/MS simultaneous bioanalytical method was developed to determine acitretin and its metabolite isoacitretin in human plasma using acitretin‐d3 used…”
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Synthesis, antispasmodic and antidiarrheal activities of some 1-substituted imidazole derivatives
Published in Acta pharmaceutica (Zagreb, Croatia) (01-06-2011)“…A series of 1-substituted imidazoles 1a-d and 2a-d were synthesized and screened for antispasmodic and antidiarrheal activities. Antispasmodic activity was…”
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In Vitro Antihistaminic Activity of Some 1-Substituted Imidazoles: H^sub 2^-Receptor Antagonism
Published in Journal of pharmaceutical sciences and research (01-01-2011)Get full text
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