Search Results - "Sasinowski, Maciek"

Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma by Neely, Benjamin A, Wilkins, Christopher E, Marlow, Laura A, Malyarenko, Dariya, Kim, Yunee, Ignatchenko, Alexandr, Sasinowska, Heather, Sasinowski, Maciek, Nyalwidhe, Julius O, Kislinger, Thomas, Copland, John A, Drake, Richard R

“…Renal cell carcinoma comprises 2 to 3% of malignancies in adults with the most prevalent subtype being clear-cell RCC (ccRCC). This type of cancer is well…”
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A Swedish Population-based Study of Adverse Birth Outcomes among Pregnant Women Treated with Buprenorphine or Methadone: Preliminary Findings by Wurst, Keele E., Zedler, Barbara K., Joyce, Andrew R., Sasinowski, Maciek, Murrelle, E. Lenn

“…Background Untreated opioid dependence in pregnant women is associated with adverse birth outcomes. Buprenorphine and methadone are options for opioid agonist…”
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Discordance between apolipoprotein B and low-density lipoprotein particle number is associated with insulin resistance in clinical practice by Varvel, Stephen A., PhD, Dayspring, Thomas D., MD, Edmonds, Yvette, PhD, Thiselton, Dawn L., PhD, Ghaedi, Leila, PhD, Voros, Szilard, MD, McConnell, Joseph P., PhD, Sasinowski, Maciek, MD, PhD, Dall, Tara, MD, Warnick, G. Russell, MSc, MBA

“…Background Discordance between measures of atherogenic lipoprotein particle number (apolipoprotein B [ApoB] and low-density lipoprotein [LDL] particle number…”
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Rice transposable elements: a survey of 73,000 sequence-tagged-connectors by Mao, L, Wood, T C, Yu, Y, Budiman, M A, Tomkins, J, Woo, S, Sasinowski, M, Presting, G, Frisch, D, Goff, S, Dean, R A, Wing, R A

“…As part of an international effort to sequence the rice genome, the Clemson University Genomics Institute is developing a sequence-tagged-connector (STC)…”
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Comparison of cardiometabolic risk biomarkers from a national clinical laboratory with the US adult population by Wolin, Elliott, PhD, White, Justin, MS, Pottala, James V., PhD, Sasinowski, Maciek, PhD, MD, Dall, Tara, MD, Dayspring, Thomas D., MD, McConnell, Joseph P., PhD, Hoefner, Daniel M., PhD, Varvel, Stephen A., PhD, Thiselton, Dawn L., PhD, Warnick, G. Russell, MS, Harris, William S., PhD

“…Background Clinical laboratory patient databases are an untapped source of valuable diagnostic and prognostic information. However, the lack of associated…”
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Familial Hypercholesterolemia Prevalence of 1.5% in a Clinical Database of 542,214 Patients: Refined Risk Stratification Using ApoB:LDL-C Ratio by Varvel, Stephen A., PhD, Voros, Szilard, MD, Thiselton, Dawn, PhD, Dall, Tara, MD, Sasinowski, Maciek, MD, PhD, McConnell, Joseph, PhD, Ueda, Masako, PhD, Warnick, Russ, MS, MBA

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Biomarkers of Cholesterol Homeostasis in a Clinical Laboratory Database Sample Comprising 667,718 Patients by Dayspring, Thomas D., MD, Varvel, Stephen A., PhD, Ghaedi, Leila, PhD, Thiselton, Dawn L., PhD, Bruton, James, MS, Sasinowski, Maciek, MD, PhD, McConnell, Joseph P., PhD

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Precision enhancement of MALDI-TOF MS using high resolution peak detection and label-free alignment by Tracy, Maureen B, Chen, Haijian, Weaver, Dennis M, Malyarenko, Dariya I, Sasinowski, Maciek, Cazares, Lisa H, Drake, Richard R, Semmes, O. John, Tracy, Eugene R, Cooke, William E

“…We have developed an automated procedure for aligning peaks in multiple TOF spectra that eliminates common timing errors and small variations in spectrometer…”
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Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration by von Roemeling, Christina A., Marlow, Laura A., Radisky, Derek C., Rohl, Austin, Larsen, Hege E., Wei, Johnny, Sasinowska, Heather, Zhu, Heng, Drake, Richard, Sasinowski, Maciek, Tun, Han W., Copland, John A.

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Validation of an administrative claims coding algorithm for serious opioid overdose: A medical chart review by Mountcastle, Sally B., Joyce, Andrew R., Sasinowski, Maciek, Costello, Nancy, Doshi, Snehal, Zedler, Barbara K.

“…Purpose A standardized definition for serious opioid overdose has not been clearly established for disease surveillance or assessing the impact of risk…”
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From Value Assessment to Value Cocreation: Informing Clinical Decision-Making with Medical Claims Data by Thompson, Steven, Varvel, Stephen, Sasinowski, Maciek, Burke, James P

“…Big data and advances in analytical processes represent an opportunity for the healthcare industry to make better evidence-based decisions on the value…”
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A Swedish population-based study of adverse birth outcomes among pregnant women treated with buprenorphine or methadone: preliminary findings by Wurst, Keele E, Zedler, Barbara K, Joyce, Andrew R, Sasinowski, Maciek, Murrelle, E. Lenn

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Comprehensive Biomarker Testing of Glycemia, Insulin Resistance, and Beta Cell Function Has Greater Sensitivity to Detect Diabetes Risk Than Fasting Glucose and HbA1c and Is Associated with Improved Glycemic Control in Clinical Practice by Varvel, Stephen A., Voros, Szilard, Thiselton, Dawn L., Pottala, James V., Dall, Tara, Warnick, G. Russell, McConnell, Joseph P., Ghaedi, Leila, Sasinowski, Maciek, Graham, Timothy

“…Blood-based biomarker testing of insulin resistance (IR) and beta cell dysfunction may identify diabetes risk earlier than current glycemia-based approaches…”
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Enhancement of Sensitivity and Resolution of Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometric Records for Serum Peptides Using Time-Series Analysis Techniques by Malyarenko, Dariya I, Cooke, William E, Adam, Bao-Ling, Malik, Gunjan, Chen, Haijian, Tracy, Eugene R, Trosset, Michael W, Sasinowski, Maciek, Semmes, O. John, Manos, Dennis M

“…Measurement of peptide/protein concentrations in biological samples for biomarker discovery commonly uses high-sensitivity mass spectrometers with a…”
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A Swedish Population-based Study of Adverse Birth Outcomes among Pregnant Women Treated with Buprenorphine or Methadone: Preliminary Findings by Keele E. Wurst, Barbara K. Zedler, Andrew R. Joyce, Maciek Sasinowski, E. Lenn Murrelle

“…Background Untreated opioid dependence in pregnant women is associated with adverse birth outcomes. Buprenorphine and methadone are options for opioid agonist…”
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Serum α-hydroxybutyrate (α-HB) predicts elevated 1 h glucose levels and early-phase β-cell dysfunction during OGTT by Varvel, Stephen A, Pottala, James V, Thiselton, Dawn L, Caffrey, Rebecca, Dall, Tara, Sasinowski, Maciek, McConnell, Joseph P, Warnick, G Russell, Voros, Szilard, Graham, Timothy E

“…Objective Serum α-hydroxybutyrate (α-HB) is elevated in insulin resistance and diabetes. We tested the hypothesis that the α-HB level predicts abnormal 1 h…”
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Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration by Von Roemeling, Christina A, Marlow, Laura A, Radisky, Derek C, Rohl, Austin, Larsen, Hege Ekeberg, Wei, Johnny, Sasinowska, Heather, Zhu, Heng, Drake, Richard, Sasinowski, Maciek, Tun, Han W, Copland, John A

“…Currently there is a lack of targeted therapies that lead to long-term attenuation or regression of disease in patients with advanced clear cell renal cell…”
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What is mzXML good for? by Lin, Simon M, Zhu, Lihua, Winter, Andrew Q, Sasinowski, Maciek, Kibbe, Warren A

“…mzXML (extensible markup language) is one of the pioneering data formats for mass spectrometry-based proteomics data collection. It is an open data format that…”
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Serum [alpha]-hydroxybutyrate ([alpha]-HB) predicts elevated 1 h glucose levels and early-phase [beta]-cell dysfunction during OGTT by Varvel, Stephen A, Pottala, James V, Thiselton, Dawn L, Caffrey, Rebecca, Dall, Tara, Sasinowski, Maciek, McConnell, Joseph P, Warnick, G Russell, Voros, Szilard, Graham, Timothy E

“…Objective Serum α-hydroxybutyrate (α-HB) is elevated in insulin resistance and diabetes. We tested the hypothesis that the α-HB level predicts abnormal 1 h…”
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Resampling and deconvolution of linear time-of-flight records for enhanced protein profiling by Malyarenko, Dariya I., Cooke, William E., Tracy, Eugene R., Drake, Richard R., Shin, Susanna, Semmes, O. John, Sasinowski, Maciek, Manos, Dennis M.

“…We have developed a peak deconvolution strategy that is applicable to the full mass range of a time‐of‐flight (TOF) spectrum. This strategy involves resampling…”
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