Search Results - "Sasiadek, Maria"

Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine by Supplitt, Stanislaw, Karpinski, Pawel, Sasiadek, Maria, Laczmanska, Izabela

“…Over the last decades, transcriptome profiling emerged as one of the most powerful approaches in oncology, providing prognostic and predictive utility for…”
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Expression Analysis of Tyrosine Phosphatase Genes at Different Stages of Renal Cell Carcinoma by LACZMANSKA, IZABELA, LACZMANSKI, LUKASZ, SASIADEK, MARIA M.

“…Background: Renal cell carcinoma (RCC) is a common urological cancer, and its risk correlates with environmental factors such as obesity, smoking and…”
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Genetic testing—whether to allow complete freedom? Direct to consumer tests versus genetic tests for medical purposes by Malgorzata, Madej, Maria, Sąsiadek, Michał, Witt

“…Direct-to-consumer tests opened the opportunity of genetic testing without medical supervision, e.g., without medical referral and medical interpretation of…”
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Physical Activity and DNA Methylation in Humans by Światowy, Witold Józef, Drzewiecka, Hanna, Kliber, Michalina, Sąsiadek, Maria, Karpiński, Paweł, Pławski, Andrzej, Jagodziński, Paweł Piotr

“…Physical activity is a strong stimulus influencing the overall physiology of the human body. Exercises lead to biochemical changes in various tissues and exert…”
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Meta-analysis of association between Arg326Gln (rs1503185) and Gln276Pro (rs1566734) polymorphisms of PTPRJ gene and cancer risk by Laczmanska, Izabela, Sasiadek, Maria M.

“…Protein tyrosine phosphatase receptor type J ( PTPRJ , DEP1 ) is a tumour suppressor gene that negatively regulates such processes as angiogenesis, cell…”
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The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients by Gil, Justyna, Ramsey, David, Pawlowski, Pawel, Szmida, Elzbieta, Leszczynski, Przemyslaw, Bebenek, Marek, Sasiadek, Maria M.

“…Despite great progress in research on the subject, the involvement of autophagy in colorectal cancer (CRC) pathogenesis (initiation, progression, metastasis)…”
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Response to the commentary by Gholami and Amoli by Laczmanska, Izabela, Sasiadek, Maria M.

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The Regulation of Collagen Processing by miRNAs in Disease and Possible Implications for Bone Turnover by Lehmann, Tomasz P, Guderska, Urszula, Kałek, Klaudia, Marzec, Maria, Urbanek, Agnieszka, Czernikiewicz, Alicja, Sąsiadek, Maria, Karpiński, Paweł, Pławski, Andrzej, Głowacki, Maciej, Jagodziński, Paweł P

“…This article describes several recent examples of miRNA governing the regulation of the gene expression involved in bone matrix construction. We present the…”
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Genetic Factors Involved in Mandibular Prognathism by Doraczynska-Kowalik, Anna, Nelke, Kamil H, Pawlak, Wojciech, Sasiadek, Maria M, Gerber, Hanna

“…Mandibular prognathism is defined as an abnormal forward projection of the mandible beyond the standard relation to the cranial base and it is usually…”
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Chromosome Aberrations and Gene Mutations in Patients With Esophageal Atresia by Bednarczyk, Damian, Sasiadek, Maria M., Smigiel, Robert

“…ABSTRACT Esophageal atresia (EA) is one of the most frequent congenital malformations of the gastrointestinal tract. Many genetic alterations in patients with…”
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Pan-cancer analysis reveals presence of pronounced DNA methylation drift in CpG island methylator phenotype clusters by Karpinski, Pawel, Pesz, Karolina, Sasiadek, Maria M

“…To provide characteristics of major genomic correlates in CpG island methylator phenotype-high (CIMP-H) subgroups in relation to corresponding non-CIMP-H…”
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Alterations in the expression of homologous recombination repair (HRR) genes in breast cancer tissues considering germline BRCA1/2 mutation status by Laczmanska, Izabela, Matkowski, Rafal, Supplitt, Stanislaw, Karpinski, Pawel, Abrahamowska, Mariola, Laczmanski, Lukasz, Maciejczyk, Adam, Czykalko, Ewelina, Iwaneczko, Ewelina, Kasprzak, Piotr, Szynglarewicz, Bartłomiej, Sasiadek, Maria

“…Introduction Homologous recombination (HR) is a crucial DNA-repair mechanism, and its disruption can lead to the accumulation of mutations that initiate and…”
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Homozygous mutation in the Neurofascin gene affecting the glial isoform of Neurofascin causes severe neurodevelopment disorder with hypotonia, amimia and areflexia by Smigiel, Robert, Sherman, Diane L, Rydzanicz, Małgorzata, Walczak, Anna, Mikolajkow, Dorota, Krolak-Olejnik, Barbara, Kosińska, Joanna, Gasperowicz, Piotr, Biernacka, Anna, Stawinski, Piotr, Marciniak, Malgorzata, Andrzejewski, Witalij, Boczar, Maria, Krajewski, Paweł, Sasiadek, Maria M, Brophy, Peter J, Ploski, Rafal

“…Abstract The Neurofascins (NFASCs) are a family of proteins encoded by alternative transcripts of NFASC that cooperate in the assembly of the node of Ranvier…”
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Giant intracerebral schwannoma of the skull base misinterpreted as a macroprolactinoma by Zięba, Sara, Sąsiadek, Maria, Łaczmańska, Izabela, Czapiga, Bogdan, Gajdzis, Paweł, Bladowska, Joanna

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The BAX gene as a candidate for negative autophagy-related genes regulator on mRNA levels in colorectal cancer by Gil, Justyna, Ramsey, David, Szmida, Elzbieta, Leszczynski, Przemyslaw, Pawlowski, Pawel, Bebenek, Marek, Sasiadek, Maria M.

“…Autophagy is a catabolic process, which is involved in the maintenance of intracellular homeostasis by degrading redundant molecules and organelles. Autophagy…”
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High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues by Laczmanska, Izabela, Karpinski, Pawel, Gil, Justyna, Laczmanski, Lukasz, Bebenek, Marek, Sasiadek, Maria M

“…The risk of sporadic colorectal cancer (CRC) is strongly influenced by Iifestyle, environmental and genetic factors. Protein tyrosine phosphatases belong to a…”
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High-Resolution Array Comparative Genomic Hybridization Utility in Polish Newborns with Isolated Cleft Lip and Palate by Szczałuba, Krzysztof, Nowakowska, Beata A, Sobecka, Katarzyna, Smyk, Marta, Castaneda, Jennifer, Dudkiewicz, Zofia, Kutkowska-Kaźmierczak, Anna, Sąsiadek, Maria M, Śmigiel, Robert, Bocian, Ewa

“…Cleft lip with or without cleft palate is one of the most common birth defects of unknown etiology. A fraction of its genetic causes is attributable to copy…”
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Tyrosine phosphatases as a superfamily of tumor suppressors in colorectal cancer by Laczmanska, Izabela, Sasiadek, Maria M

“…Phosphorylation and dephosphorylation processes catalyzed by numerous kinases and phosphorylases are essential for cell homeostasis and may lead to…”
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Phenotypic expansion in Zhu‐Tokita‐Takenouchi‐Kim syndrome caused by de novo variants in the SON gene by Slezak, Ryszard, Smigiel, Robert, Rydzanicz, Malgorzata, Pollak, Agnieszka, Kosinska, Joanna, Stawinski, Piotr, Malgorzata Sasiadek, Maria, Ploski, Rafal

“…Background The genetic etiology of intellectual and psychomotor disability without a defined spectrum of dysmorphic features is usually monogenic. As no…”
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The analysis of transcriptomic signature of TNBC—searching for the potential RNA-based predictive biomarkers to determine the chemotherapy sensitivity by Supplitt, Stanislaw, Karpinski, Pawel, Sasiadek, Maria, Laczmanski, Lukasz, Kujawa, Dorota, Matkowski, Rafal, Kasprzak, Piotr, Abrahamowska, Mariola, Maciejczyk, Adam, Iwaneczko, Ewelina, Laczmanska, Izabela

“…Neoadjuvant chemotherapy is the foundation treatment for triple-negative breast cancer (TNBC) and frequently results in pathological complete response (pCR)…”
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