Search Results - "Sasamoto, Kazumi"
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Small fluorescent molecules for monitoring autophagic flux
Published in FEBS letters (01-02-2018)“…We have developed two types of fluorescent probes, DALGreen and DAPGreen, for monitoring autophagy, that exhibit fluorescence upon being incorporated into…”
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Glyceraldehyde-derived advanced glycation end-products having pyrrolopyridinium-based crosslinks
Published in Biochemistry and biophysics reports (01-07-2021)“…Reducing sugars and reactive aldehydes, such as glyceraldehyde, non-enzymatically react with amino or guanidino groups of proteins to form advanced glycation…”
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A novel crosslinked type of advanced glycation end-product derived from lactaldehyde
Published in Heliyon (01-11-2020)“…Glycation of amino or guanidino groups of proteins with glucose and glucose-derived reactive aldehydes, such as α-hydroxyaldehydes, leads to accumulation of…”
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8-Nitroguanosine Formation in Viral Pneumonia and Its Implication for Pathogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2003)“…For many diseases, mediation of pathogenesis by nitric oxide (NO) has been suggested. In this study, we explored NO-induced viral pathogenesis with a focus on…”
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A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet
Published in Biological & pharmaceutical bulletin (1996)“…Cell viability and in vitro cytotoxicity assay methods were developed using a combination of dyes,…”
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Applicability of new spin trap agent, 2-diphenylphosphinoyl-2-methyl-3,4-dihydro-2H-pyrrole N-oxide, in biological system
Published in Biochemical and biophysical research communications (23-05-2008)“…Electron spin resonance using spin-trapping is a useful technique for detecting direct reactive oxygen species, such as superoxide (O2.-). However, the widely…”
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Monitoring Lipid Droplet Dynamics in Living Cells by Using Fluorescent Probes
Published in Biochemistry (Easton) (12-02-2019)“…We have developed three types of lipid droplet (LD)-specific fluorescent probes for live-cell imaging, Lipi-Blue, Lipi-Green, and Lipi-Red, which exhibit…”
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Live Cell Imaging of Mitochondrial Autophagy with a Novel Fluorescent Small Molecule
Published in ACS chemical biology (20-10-2017)“…There has been a growing interest in mitophagy, mitochondria-selective autophagy, which plays an essential role in maintaining intracellular homeostasis. We…”
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A Novel Tool for Detecting Amyloid Deposits in Systemic Amyloidosis In Vitro and In Vivo
Published in Laboratory investigation (01-12-2003)“…We synthesized (trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB) and used this compound to detect amyloid fibrils in autopsy and…”
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A New Water-soluble Chromogenic Indicator: An Application to the Determination of Chlorine in Aqueous Solutions
Published in Analytical Sciences (2003)“…A novel compound, N,N"-bis(2,4-di-sulfobenzyl)tolidine tetrasodium salt (SBT), was synthesized for use as a chromogenic indicator for oxidizing substances, and…”
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Novel styrylbenzene derivatives for detecting amyloid deposits
Published in Clinica chimica acta (25-09-2014)“…Various styrylbenzene compounds were synthesized and evaluated as mainly Aβ amyloid sensors. These compounds, however, cannot be used for detecting amyloid…”
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P109 Development of chemical reagents for H2S study
Published in Nitric oxide (30-05-2014)“…Dojindo Laboratories develops, produces and markets chemical reagents worldwide useful for life science research such as calcium ion (Ca2+) or nitric oxide…”
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Precolumn Fluorescence Derivatization of Carboxylic Acids Using 4-Aminomethyl-6, 7-dimethoxycoumarin in a Two-Phase Medium
Published in Analytical Sciences (1996)“…A new coumarin-based amine, 4-aminomethyl-6, 7-dimethoxycoumarin, was synthesized as a precolumn fluorescence derivatization reagent for carboxylic acids. The…”
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A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability
Published in Talanta (Oxford) (01-07-1997)“…A highly water soluble disulfonated tetrazolium salt, 4-[3-(2-methoxy-4-nitrophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate sodium salt,…”
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Superoxide scavenging activity of pirfenidone–iron complex
Published in Biochemical and biophysical research communications (18-07-2008)“…Pirfenidone (PFD) is focused on a new anti-fibrotic drug, which can minimize lung fibrosis etc. We evaluated the superoxide ( O 2 − ) scavenging activities of…”
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Benzothiazole-containing tetrazolium salts that produce water-soluble formazan dyes absorbing at a long wavelength upon NADH reduction
Published in Analytical sciences (01-06-1996)Get full text
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A Novel Method for Determining Peroxidase Activities Using p-Acetamidophenol Analogs
Published in Analytical Sciences (1995)“…p-Acetamidophenol analogs were proved to produce highly fluorescent compounds upon oxidation with peroxidase and hydrogen peroxide. The chemical structure of…”
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2-(5-Hydrazinocarbonyl-2-furyl)-5, 6-dimethoxybenzothiazole as a Precolumn Fluorescence Derivatization Reagent for Carboxylic Acids in High-Performance Liquid Chromatography and Its Application to the Assay of Fatty Acids in Human Serum
Published in Analytical Sciences (1995)“…A precolumn fluorescence derivatization reagent for carboxylic acids, 2-(5-hydrazinocarbonyl-2-furyl)-5, 6-dimethoxybenzothiazole, was developed and its…”
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Development of a Protein-free Medium with Iron Salts Replacing Transferrin for a Human-Human Hybridoma
Published in Bioscience, biotechnology, and biochemistry (1995)“…Many protein-free media have been deveoped, because protein-free media are usually more economical than serum-free or serumcontaining media and facilitate the…”
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