Search Results - "Sasajima, Sachiko"
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Thermal gradient ring reveals different temperature-dependent behaviors in mice lacking thermosensitive TRP channels
Published in The journal of physiological sciences (26-05-2022)“…Transient receptor potential (TRP) channels are known as temperature receptors. Each channel has an activation temperature in vitro within the physiological…”
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2
Porphyromonas gingivalis Lipopolysaccharides Promote Proliferation and Migration of Human Vascular Smooth Muscle Cells through the MAPK/TLR4 Pathway
Published in International journal of molecular sciences (21-12-2022)“…Atherosclerosis is a major cause of mortality worldwide. The initial change in atherosclerosis is intimal thickening due to muscle cell proliferation and…”
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Dipeptidyl Peptidase (DPP)-4 Inhibitors and Pituitary Adenylate Cyclase-Activating Polypeptide, a DPP-4 Substrate, Extend Neurite Outgrowth of Mouse Dorsal Root Ganglia Neurons: A Promising Approach in Diabetic Polyneuropathy Treatment
Published in International journal of molecular sciences (15-08-2024)“…Individuals suffering from diabetic polyneuropathy (DPN) experience debilitating symptoms such as pain, paranesthesia, and sensory disturbances, prompting a…”
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Increased expression of angiopoietin‐like protein 4 regulates matrix metalloproteinase‐13 expression in Porphyromonas gingivalis lipopolysaccharides‐stimulated gingival fibroblasts and ligature‐induced experimental periodontitis
Published in Journal of periodontal research (01-02-2023)“…Background Angiopoietin‐like protein 4 (ANGPTL4) is produced in chronic or acute inflammation. Although ANGPTL4 increases in the periodontal ligament…”
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5
Thermal gradient ring reveals thermosensory changes in diabetic peripheral neuropathy in mice
Published in Scientific reports (13-06-2022)“…Diabetic peripheral neuropathy (DPN) includes symptoms of thermosensory impairment, which are reported to involve changes in the expression or function, or…”
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Simplified electrophysiological approach combining a point‐of‐care nerve conduction device and an electrocardiogram produces an accurate diagnosis of diabetic polyneuropathy
Published in Journal of diabetes investigation (01-06-2024)“…Aims/Introduction This study aimed to investigate the diagnostic potential of two simplified tests, a point‐of‐care nerve conduction device (DPNCheck™) and a…”
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7
Clinical parameters correlated with the psoas muscle index in Japanese individuals with type 2 diabetes mellitus
Published in Diabetology international (01-01-2023)“…Aims Muscle atrophy is a diabetic complication, which results in a deterioration in glycemic control in type 2 diabetes mellitus (T2DM) individuals. The psoas…”
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Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves
Published in iScience (21-01-2022)“…Glucose-responsive ATP-sensitive potassium channels (KATP) are expressed in a variety of tissues including nervous systems. The depolarization of the membrane…”
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Secreted Factors from Stem Cells of Human Exfoliated Deciduous Teeth Directly Activate Endothelial Cells to Promote All Processes of Angiogenesis
Published in Cells (Basel, Switzerland) (31-10-2020)“…Diabetes is a major risk factor for atherosclerosis and ischemic vascular diseases. Recently, regenerative medicine is expected to be a novel therapy for…”
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491-P: Transplantation of Dental Pulp Stem Cells Ameliorates Diabetic Muscle Atrophy and Inflammation and Improves Diabetic Peripheral Neuropathy
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Objectives: Diabetic peripheral neuropathy is associated with neurogenic muscle atrophy. The development of successful therapies for nerve damage and muscle…”
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1485-P: The Involvement of ANGPTL4 in Periodontitis and the Influence of High Glucose
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Periodontitis is a chronic inflammatory disease in which periodontal tissue is destroyed by bacterial infection. Periodontal disease is considered a…”
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Impacts of Hyperglycemia on Epigenetic Modifications in Human Gingival Fibroblasts and Gingiva in Diabetic Rats
Published in International journal of molecular sciences (12-10-2024)“…Periodontal disease is considered one of the diabetic complications with high morbidity and severity. Recent studies demonstrated the involvement of the…”
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Mechanical loading-induced alveolar bone remodeling is suppressed in the diabetic state via the impairment of the specificity protein 1/vascular endothelial growth factor (SP1/VEGF) axis
Published in Journal of diabetes investigation (26-10-2024)“…Orthodontic treatment involves alveolar bone remodeling in response to mechanical loading, resulting in tooth movement through traction-side bone formation and…”
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14
Deficiency of glucagon gene-derived peptides induces peripheral polyneuropathy in mice
Published in Biochemical and biophysical research communications (29-10-2020)“…Although diabetic polyneuropathy (DPN) is the commonest diabetic complication, its pathology remains to be clarified. As previous papers have suggested the…”
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