Search Results - "Sarver, C"
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Insulin‐like growth factor 1 signaling in tenocytes is required for adult tendon growth
Published in The FASEB journal (01-11-2019)“…Tenocytes serve to synthesize and maintain collagen fibrils and other extracellular matrix proteins in tendon. Despite the high prevalence of tendon injury,…”
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2
Characterizing novel olfactory receptors expressed in the murine renal cortex
Published in American journal of physiology. Renal physiology (01-07-2019)“…The kidney uses specialized G protein-coupled receptors, including olfactory receptors (ORs), to act as sensors of molecules and metabolites. In the present…”
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3
Sex differences in tendon structure and function
Published in Journal of orthopaedic research (01-10-2017)“…ABSTRACT Tendons play a critical role in the transmission of forces between muscles and bones, and chronic tendon injuries and diseases are among the leading…”
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4
Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal acquisition
Published in eLife (19-01-2024)“…Genome-wide association studies (GWAS) have identified a large number of candidate genes believed to affect longitudinal bone growth and bone mass. One of…”
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5
Hypermetabolism in mice carrying a near-complete human chromosome 21
Published in eLife (30-05-2023)“…The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we…”
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Responsiveness and meaningful thresholds of PROMIS pain interference, fatigue, and physical function forms in adults with idiopathic inflammatory myopathies: Report from the OMERACT Myositis Working Group
Published in Seminars in arthritis and rheumatism (01-02-2024)“…A series of qualitative studies conducted by the OMERACT Myositis Working Group identified pain interference, fatigue, and physical function as highly…”
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Inhibition of p38 mitogen-activated protein kinase signaling reduces fibrosis and lipid accumulation after rotator cuff repair
Published in Journal of shoulder and elbow surgery (01-09-2016)“…Background The repair of rotator cuff tears is often complicated by fatty degeneration, which is the combination of lipid accumulation, fibrosis, inflammation,…”
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Dysregulated systemic metabolism in a Down syndrome mouse model
Published in Molecular metabolism (Germany) (01-02-2023)“…Trisomy 21 is one of the most complex genetic perturbations compatible with postnatal survival. Dosage imbalance arising from the triplication of genes on…”
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CTRP13 ablation improves systemic glucose and lipid metabolism
Published in Molecular metabolism (Germany) (01-12-2023)“…Tissue crosstalk mediated by secreted hormones underlies the integrative control of metabolism. We previously showed that CTRP13/C1QL3, a secreted protein of…”
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p38 MAPK signaling in postnatal tendon growth and remodeling
Published in PloS one (13-03-2015)“…Tendon is a dynamic tissue whose structure and function is influenced by mechanical loading, but little is known about the fundamental mechanisms that regulate…”
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Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle
Published in Scientific reports (25-05-2017)“…Cryotherapy is commonly used in the treatment of skeletal muscle injuries. However, the data to support the use of cryotherapy is inconclusive, and the…”
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Advancing the Development of Patient-reported Outcomes for Adult Myositis at OMERACT 2016: An International Delphi Study
Published in JOURNAL OF RHEUMATOLOGY (01-07-2018)Get full text
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Advancing the Development of Patient-reported Outcomes for Adult Myositis at OMERACT 2016: An International Delphi Study
Published in JOURNAL OF RHEUMATOLOGY (01-12-2017)Get full text
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14
Obesity alters Ace2 and Tmprss2 expression in lung, trachea, and esophagus in a sex-dependent manner: Implications for COVID-19
Published in Biochemical and biophysical research communications (29-01-2021)“…Obesity is a major risk factor for SARS-CoV-2 infection and COVID-19 severity. The underlying basis of this association is likely complex in nature. The…”
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15
Prostaglandin D2 signaling is not involved in the recovery of rat hind limb tendons from injury
Published in Physiological reports (01-11-2019)“…Injured tendons heal through the formation of a fibrovascular scar that has inferior mechanical properties compared to native tendon tissue. Reducing…”
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Caring: The heart of online nursing education- An integrative review
Published in Journal of professional nursing (01-05-2024)“…With the widespread adoption of online education, nursing educators have observed significant challenges related to learner engagement and participation. Over…”
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CTRP14 inactivation alters physical activity and food intake response to fasting and refeeding
Published in American journal of physiology: endocrinology and metabolism (01-06-2022)“…Secreted proteins of the C1q/TNF-related protein (CTRP) family play diverse functions in different organ systems. In the brain, CTRP14/C1QL1 is required for…”
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Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells
Published in JCI insight (17-09-2020)“…Specialized proresolving mediators (SPMs) actively limit inflammation and expedite its resolution by modulating leukocyte recruitment and function. Here we…”
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Myonectin deletion promotes adipose fat storage and reduces liver steatosis
Published in The FASEB journal (01-07-2019)“…ABSTRACT We recently described myonectin (also known as erythroferrone) as a novel skeletal muscle‐derived myokine with metabolic functions. Here, we use a…”
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Loss of CTRP4 alters adiposity and food intake behaviors in obese mice
Published in American journal of physiology: endocrinology and metabolism (01-12-2020)“…Central and peripheral mechanisms are both required for proper control of energy homeostasis. Among circulating plasma proteins, C1q/TNF-related proteins…”
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