Search Results - "Sarvari, Sajad"
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Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke
Published in Metabolic brain disease (01-08-2020)“…Stroke is the leading cause of disability among adults as well as the 2nd leading cause of death globally. Ischemic stroke accounts for about 85% of strokes,…”
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Electron Spin Resonance Probe Incorporation into Bioinks Permits Longitudinal Oxygen Imaging of Bioprinted Constructs
Published in Molecular imaging and biology (01-06-2024)“…Purpose Bioprinting is an additive manufacturing technology analogous to 3D printing. Instead of plastic or resin, cell-laden hydrogels are used to produce a…”
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The Role of HSA21 Encoded Mirna in Down Syndrome Pathophysiology:Opportunities in miRNA-Targeted Pharmacotherapy and Diagnosis of the Down Syndrome
Published in Pharmaceutical Sciences (01-09-2021)“…Trisomy 21 is the most prevalent aneuploidy disorder among live-born children worldwide. Itresults from the presence of an extra copy of chromosome 21 which…”
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Targeting the microRNA binding domain of argonaute 2: rational inhibitor design and study of mutation effects on protein-ligand interaction
Published in Journal of biomolecular structure & dynamics (01-11-2020)“…Based on the accumulative evidences during recent decades, miRNAs have been found overexpressed in several human cancer types and also in Down syndrome…”
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Targeted protein modification as a paradigm shift in drug discovery
Published in European journal of medicinal chemistry (15-11-2023)“…Targeted Protein Modification (TPM) is an umbrella term encompassing numerous tools and approaches that use bifunctional agents to induce a desired…”
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Novel therapeutic strategies for Alzheimer's disease: Implications from cell-based therapy and nanotherapy
Published in Nanomedicine (01-02-2020)“…Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which leads to progressive dysfunction of cognition, memory and learning in elderly…”
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Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions
Published in International journal of nanomedicine (01-01-2020)“…The advent of porous materials, in particular zeolitic nanoparticles, has opened up unprecedented putative research avenues in nanomedicine. Zeolites with…”
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High carotenoid production by a halotolerant bacterium, Kocuria sp. strain QWT-12 and anticancer activity of its carotenoid
Published in EXCLI journal (01-01-2017)“…Halophilic prokaryotes are extremophile microorganisms that grow optimally in media containing salts and almost appeared pigmented. Many of them contain high…”
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Biomolecular Corona Dictates Aβ Fibrillation Process
Published in ACS chemical neuroscience (18-07-2018)“…Amyloid beta (Aβ), which forms toxic oligomers and fibrils in brain tissues of patients with Alzheimer’s disease, is broadly used as a model protein to probe…”
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