Search Results - "Saruta, T."

Long-term effects of statins on arterial pressure and stiffness of hypertensives by ICHIHARA, A, HAYASHI, M, KOURA, Y, TADA, Y, KANESHIRO, Y, SARUTA, T

“…Although lowering blood pressure (BP) reduces aortic stiffness, achieving the recommended BP goal can be difficult. Recent studies have shown that short-term…”
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T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy by Sugano, N., Wakino, S., Kanda, T., Tatematsu, S., Homma, K., Yoshioka, K., Hasegawa, K., Hara, Y., Suetsugu, Y., Yoshizawa, T., Hara, Y., Utsunomiya, Y., Tokudome, G., Hosoya, T., Saruta, T., Hayashi, K.

“…T-type calcium channel blockers have been previously shown to protect glomeruli from hypertension by regulating renal arteriolar tone. To examine whether…”
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Awareness of the Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2000) and compliance to its recommendations: surveys in 2000 and 2004 by IKEDA, N, HASEGAWA, T, HASEGAWA, T, SAITO, I, SARUTA, T

“…Clinic physicians' awareness of the Japanese hypertension guideline (JSH 2000) and compliance with its recommendations were assessed to derive policy…”
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High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project by Kato, Norihiro, Miyata, Toshiyuki, Tabara, Yasuharu, Katsuya, Tomohiro, Yanai, Kazuyuki, Hanada, Hironori, Kamide, Kei, Nakura, Jun, Kohara, Katsuhiko, Takeuchi, Fumihiko, Mano, Hiroyuki, Yasunami, Michio, Kimura, Akinori, Kita, Yoshikuni, Ueshima, Hirotsugu, Nakayama, Tomohiro, Soma, Masayoshi, Hata, Akira, Fujioka, Akihiro, Kawano, Yuhei, Nakao, Kazuwa, Sekine, Akihiro, Yoshida, Teruhiko, Nakamura, Yusuke, Saruta, Takao, Ogihara, Toshio, Sugano, Sumio, Miki, Tetsuro, Tomoike, Hitonobu

“…Essential hypertension is one of the most common, complex diseases, of which considerable efforts have been made to unravel the pathophysiological mechanisms…”
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Role of actions of calcium antagonists on efferent arterioles--with special references to glomerular hypertension by Hayashi, Koichi, Ozawa, Yuri, Fujiwara, Keiji, Wakino, Shu, Kumagai, Hiroo, Saruta, Takao

“…Although calcium antagonists are used as a first-line antihypertensive agent, controversy attends the renal microvascular effects of calcium antagonists. Since…”
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Oxidative stress induced by iron released from transferrin in low pH peritoneal dialysis solution by Yamaji, Yasuyoshi, Nakazato, Yuichi, Oshima, Naoki, Hayashi, Matsuhiko, Saruta, Takao

“…Background. Transferrin binds extracellular iron and protects tissues from iron-induced oxidative stress. The binding of iron and transferrin is pH dependent…”
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Improvement of accessory symptoms of hypertension by TSUMURA Orengedokuto Extract, a four herbal drugs containing Kampo-Medicine Granules for ethical use: A double-blind, placebo-controlled study by Arakawa, K., Saruta, T., Abe, K., Iimura, O., Ishii, M., Ogihara, T., Hiwada, K., Fukiyama, K., Fujishima, M., Mizuno, Y., Kikuchi, T., Takaori, S.

“…A double-blind, placebo-controlled study was conducted to evaluate the efficacy, safety, and utility of TSUMURA Orengedokuto Extract Granules for Ethical Use…”
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Microarray analysis of a reversible model and an irreversible model of anti-Thy-1 nephritis by Tsuji, M., Monkawa, T., Yoshino, J., Asai, M., Fukuda, S., Kawachi, H., Shimizu, F., Hayashi, M., Saruta, T.

“…A single intravenous injection of anti-Thy-1 monoclonal antibody (mAb) 1-22-3 is known to cause reversible mesangial proliferative glomerulonephritis. However,…”
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Paraoxonase 1 Gln/Arg polymorphism is associated with the risk of microangiopathy in Type 2 diabetes mellitus by Murata, M, Maruyama, T, Suzuki, Y, Saruta, T, Ikeda, Y

“…To investigate possible associations between diabetic microangiopathy and genetic polymorphisms in factors relevant to arterial thrombosis. We conducted a…”
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Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis by NAKAYA, Hideaki, SASAMURA, Hiroyuki, HAYASHI, Matsuhiko, SARUTA, Takao

“…Hypertensive nephrosclerosis is a leading cause of end-stage renal disease; therefore, strategies to prevent the development of renal disease require close…”
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Paraoxonase 1 192Gln/Arg polymorphism is associated with the risk of microangiopathy in Type 2 diabetes mellitus by Murata, M., Maruyama, T., Suzuki, Y., Saruta, T., Ikeda, Y.

“…Aims  To investigate possible associations between diabetic microangiopathy and genetic polymorphisms in factors relevant to arterial thrombosis. Methods  We…”
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Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals by Azuma, K, Oguchi, S, Matsubara, Y, Mamizuka, T, Murata, M, Kikuchi, H, Watanabe, K, Katsukawa, F, Yamazaki, H, Shimada, A, Saruta, T

“…Resistin, an adipocyte-secreted cytokine recently discovered in mice, has been proposed as a link between obesity and diabetes. We analyzed resistin gene…”
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Expert recommendations on the challenges of hypertension in Asia by Chung, N, Baek, S, Chen, M-F, Liau, C-S, Park, C G, Park, J, Saruta, T, Shimamoto, K, Wu, Z, Zhu, J, Fujita, T

“…A consensus meeting of leading Asian hypertension experts was held in January 2007 in Seoul, Korea, to discuss how to address the growing challenge of…”
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Ubc9 interacts with chicken ovalbumin upstream promoter-transcription factor I and represses receptor-dependent transcription by Kobayashi, S, Shibata, H, Kurihara, I, Yokota, K, Suda, N, Saito, I, Saruta, T

“…Chicken ovalbumin upstream promoter-transcription factors (COUP-TFs) are orphan receptors involved in regulation of neurogenesis and organogenesis. COUP-TF…”
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Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious dogs by Naitoh, M, Suzuki, H, Murakami, M, Matsumoto, A, Arakawa, K, Ichihara, A, Nakamoto, H, Oka, K, Yamamura, Y, Saruta, T

“…Rapid right ventricular pacing could induce congestive heart failure in conscious dogs with significant increase in plasma concentration of arginine…”
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Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors by SHIMIZU-HIROTA, Ryoko, SASAMURA, Hiroyuki, MIFUNE, Mizuo, NAKAYA, Hideaki, KURODA, Mari, HAYASHI, Matsuhiko, SARUTA, Takao

“…Recent studies have shown that proteoglycans play an important role in the development of vascular disease and renal failure. In this study, the effects of…”
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Local renin-angiotensin system contributes to hyperthyroidism-induced cardiac hypertrophy by Kobori, H, Ichihara, A, Miyashita, Y, Hayashi, M, Saruta, T

“…We have reported previously that thyroid hormone activates the circulating and tissue renin-angiotensin systems without involving the sympathetic nervous…”
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Blood pressure reduction associated with preservation of renal function in hypertensive patients with IgA nephropathy: a 3-year follow-up by Kanno, Y, Okada, H, Saruta, T, Suzuki, H

“…The relative importance of hypertension in the progression of renal failure is well understood. Recently, several studies have provided evidence that…”
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N-acetyl-cysteine accelerates transfer of diabetes into non-obese diabetic scid mice by IRIE, J, SHIMADA, A, OIKAWA, Y, SHIGIHARA, T, SARUTA, T

“…Type 1 diabetes mellitus is caused by autoimmune pancreatic beta cell destruction, and the destructive process involves several molecular mechanisms including…”
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Expression and distribution of aquaporin of collecting duct are regulated by vasopressin V2 receptor in rat kidney by Hayashi, M, Sasaki, S, Tsuganezawa, H, Monkawa, T, Kitajima, W, Konishi, K, Fushimi, K, Marumo, F, Saruta, T

“…To examine whether expression and distribution of aquaporin of collecting duct (AQP-CD) are regulated by vasopressin V2 receptor (V2R), we performed…”
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