Search Results - "Sartono, Erliyani"
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A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics
Published in Nature medicine (01-03-2020)“…Schistosomiasis treatment relies on the use of a single drug, praziquantel, which is insufficient to control transmission in highly endemic areas 1 . Novel…”
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Helminth infections, type-2 immune response, and metabolic syndrome
Published in PLoS pathogens (01-07-2014)“… The Association between Metabolic Syndrome and Inflammation Metabolic syndrome (MetS), a disorder of energy utilization and storage, manifests as a cluster…”
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The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies
Published in Diabetology and metabolic syndrome (07-01-2020)“…The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of…”
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Intestinal permeability before and after albendazole treatment in low and high socioeconomic status schoolchildren in Makassar, Indonesia
Published in Scientific reports (01-03-2022)“…Intestinal helminths are highly prevalent in low-SES children and could contribute to poor health outcomes either directly or via alteration of the gut…”
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5
Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia
Published in Microbiome (28-02-2018)“…The human intestine and its microbiota is the most common infection site for soil-transmitted helminths (STHs), which affect the well-being of ~ 1.5 billion…”
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Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia
Published in PLoS neglected tropical diseases (01-08-2018)“…Microbiome studies suggest the presence of an interaction between the human gut microbiome and soil-transmitted helminth. Upon deworming, a complex interaction…”
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Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity
Published in PloS one (10-06-2015)“…Given that helminth infections have been shown to improve insulin sensitivity in animal studies, which may be explained by beneficial effects on energy balance…”
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8
A longitudinal study of BCG vaccination in early childhood: the development of innate and adaptive immune responses
Published in PloS one (19-11-2010)“…BCG vaccine drives a strong T helper 1 cellular immunity which is essential for the protection against mycobacteria, however recent studies suggest that BCG…”
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Urbanization and Unfavorable Changes in Metabolic Profiles: A Prospective Cohort Study of Indonesian Young Adults
Published in Nutrients (01-08-2022)“…The substantial increase in the prevalence of non-communicable diseases in Indonesia might be driven by rapid socio-economic development through urbanization…”
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10
Effect of anthelmintic treatment on serum free IGF-1 and IGFBP-3: a cluster-randomized-controlled trial in Indonesia
Published in Scientific reports (04-11-2020)“…In children, soil-transmitted helminth infections have been linked to poor nutritional status and growth retardation in association with lower levels of IGF-1…”
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11
Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country
Published in Scientific reports (31-10-2019)“…In utero exposure to environmental factors can modify the development of allergies later in life whereby the mechanisms of the feto-maternal crosstalk still…”
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12
Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections
Published in Frontiers in immunology (06-03-2023)“…Parasitic nematodes responsible for filarial diseases cause chronic disablement in humans worldwide. Elimination programs have substantially reduced the rate…”
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13
Molecular diagnostics and lack of clinical allergy in helminth-endemic areas in Indonesia
Published in Journal of allergy and clinical immunology (01-10-2017)“…Capsule summary Allergen microarray characterization of sensitization to common allergen sources in a helminth-endemic area of Indonesia shows that helminth…”
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The Effect of Gut Microbiome Composition on Human Immune Responses: An Exploration of Interference by Helminth Infections
Published in Frontiers in genetics (06-11-2019)“…Background: Soil-transmitted helminths have been shown to have the immune regulatory capacity, which they use to enhance their long term survival within their…”
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Author Correction: Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country
Published in Scientific reports (28-01-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics
Published in PLoS neglected tropical diseases (01-05-2012)“…Infection with filarial parasites is associated with T cell hyporesponsiveness, which is thought to be partly mediated by their ability to induce regulatory T…”
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Impact of rural-urban environment on metabolic profile and response to a 5-day high-fat diet
Published in Scientific reports (25-05-2018)“…Epidemiological studies have indicated that rural living might be protective against type 2 diabetes development. We compared the metabolic profile and…”
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Relationship between carotid intima media thickness and helminth infections on Flores Island, Indonesia
Published in PloS one (24-01-2013)“…To examine the association between helminth infections and atherosclerosis. Chronic helminth infection, which can lead to poor nutritional status and…”
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The effect of three-monthly albendazole treatment on malarial parasitemia and allergy: a household-based cluster-randomized, double-blind, placebo-controlled trial
Published in PloS one (19-03-2013)“…Helminth infections are proposed to have immunomodulatory activities affecting health outcomes either detrimentally or beneficially. We evaluated the effects…”
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Longitudinal study of changes in γδ T cells and CD4+ T cells upon asymptomatic malaria infection in Indonesian children
Published in Scientific reports (18-08-2017)“…Both γδ T cells and CD4 + T cells have been implicated in immunity to malaria, but their association with natural gain or loss of infection has not been…”
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