Search Results - "Sartain, Sarah"
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Rate of thrombosis in children and adolescents hospitalized with COVID-19 or MIS-C
Published in Blood (15-07-2021)“…Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with thrombotic complications in…”
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Microvascular thrombosis: experimental and clinical implications
Published in Translational research : the journal of laboratory and clinical medicine (01-11-2020)“…A significant amount of clinical and research interest in thrombosis is focused on large vessels (eg, stroke, myocardial infarction, deep venous thrombosis,…”
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Haemolytic uraemic syndrome
Published in The Lancet (British edition) (12-11-2022)“…Haemolytic uraemic syndrome (HUS) is a heterogeneous group of diseases that result in a common pathology, thrombotic microangiopathy, which is classically…”
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Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells
Published in The Journal of biological chemistry (11-05-2018)“…Atypical hemolytic uremic syndrome (aHUS) and bone marrow transplantation-associated thrombotic microangiopathy (TA-TMA) are associated with excessive…”
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The Pathology of Pulmonary Disease After Pediatric Hematopoietic Stem Cell Transplantation
Published in The American journal of surgical pathology (01-10-2024)“…Pulmonary complications continue to cause significant morbidity and mortality in posthematopoietic stem cell transplantation (HSCT) settings. The…”
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TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells
Published in The Journal of immunology (1950) (15-01-2016)“…Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy with severe renal injury secondary to an overactive alternative complement pathway…”
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Implementing a Pediatric Pulmonary Embolism Response Team Model: An Institutional Experience
Published in Chest (01-01-2024)“…Pulmonary embolism is increasing in prevalence among pediatric patients; although still rare, it can create a significant risk for morbidity and death within…”
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Adolescent acquired thrombotic thrombocytopenic purpura: An analysis of the Pediatric Health Information System database
Published in Thrombosis research (01-02-2023)“…The outcomes and characteristics of acquired thrombotic thrombocytopenic purpura (TTP) in adolescents is poorly understood due to an absence of studies focused…”
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COVID‐19 vaccine (mRNA BNT162b2) and COVID‐19 infection‐induced thrombotic thrombocytopenic purpura in adolescents
Published in Pediatric blood & cancer (01-06-2022)“…The mRNA COVID‐19 vaccine and COVID‐19 infection caused by the SARS‐CoV‐2 virus may be immunologic triggers for the development of thrombotic thrombocytopenic…”
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Management of neonatal and infant aortic thrombosis: A single‐center case series
Published in Pediatric blood & cancer (01-11-2024)“…Neonatal and infant aortic thrombosis is a rare albeit life‐threatening thrombotic event, particularly seen in premature infants with an arterial catheter in…”
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Pulmonary embolism in pediatric and adolescent patients with COVID‐19 infection during the SARS‐CoV‐2 delta wave
Published in Pediatric blood & cancer (01-08-2022)“…Coronavirus disease 2019 (COVID‐19) infection in children has been associated with thrombosis, though few cases of COVID‐associated pulmonary embolism (PE)…”
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The alternative complement pathway activation product Ba as a marker for transplant‐associated thrombotic microangiopathy
Published in Pediatric blood & cancer (01-03-2020)“…Background Transplant‐associated thrombotic microangiopathy (TA‐TMA) occurs after hematopoietic stem cell transplantation (HSCT) and is characterized by…”
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Bleeding outcomes and management of supratherapeutic episodes secondary to warfarin in children: A single center 10-year experience
Published in Thrombosis research (01-08-2023)“…•The overall bleeding risk in children on warfarin with an INR ≥4.5 is low.•Each unit increase in INR above 4.5 is associated with a 39 % increased risk of…”
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Pulmonary Histopathologic Findings in Pediatric Patients After Hematopoietic Stem Cell Transplantation: An Autopsy Study
Published in Pediatric and developmental pathology (01-07-2023)“…Background: Pathologic characterization of pulmonary complications following hematopoietic stem cell transplantation (HSCT) is limited. We describe lung…”
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Thrombosis and thromboembolism: Brighton collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data
Published in Vaccine (19-10-2022)“…This is a Brighton Collaboration case definition of thrombosis and thromboembolism to be used in the evaluation of adverse events following immunization, and…”
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Role of anticoagulation in the management of tumor thrombus: A 10‐year single‐center experience
Published in Pediatric blood & cancer (01-09-2021)“…Background Children with cancer diagnosis are overall at a higher risk of thrombosis. For a newly diagnosed blood clot, patients are commonly started on…”
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Hospital acquired venous thromboembolism in children with sickle cell disease
Published in Pediatric hematology and oncology (02-10-2024)“…Sickle cell disease (SCD) is well recognized as a hypercoagulablestate, however, it remains unclear whether a subgroup of children with SCD at higher risk of…”
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Pathway-driven rare germline variants associated with transplant-associated thrombotic microangiopathy (TA-TMA)
Published in Thrombosis research (01-05-2023)“…The significance of rare germline mutations in transplant-associated thrombotic microangiopathy (TA-TMA) is not well studied. We performed a genetic…”
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Practical considerations and consensus opinion for children’s hospital–based inpatient hemostasis and thrombosis (HAT) consultative services: Communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis
Published in Journal of thrombosis and haemostasis (01-09-2022)“…Caring for children and adolescents with disorders of hemostasis and thrombosis (HAT) has become more specialized and requires a unique skill set that many…”
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