Search Results - "Sarrazin, C"

Regression of fibrosis and portal hypertension in HCV-associated cirrhosis and sustained virologic response after interferon-free antiviral therapy by Knop, V., Hoppe, D., Welzel, T., Vermehren, J., Herrmann, E., Vermehren, A., Friedrich-Rust, M., Sarrazin, C., Zeuzem, S., Welker, M.-W.

“…Summary It is still controversial, whether and to what amount cirrhosis and portal hypertension are reversible in patients with hepatitis C virus…”
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New HCV therapies on the horizon by Vermehren, J., Sarrazin, C.

“…Improved understanding of the hepatitis C virus (HCV) life cycle has led to the discovery of numerous potential targets for antiviral therapy. HCV polyprotein…”
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Review article: specifically targeted anti‐viral therapy for hepatitis C – a new era in therapy by Lange, C. M., Sarrazin, C., Zeuzem, S.

“…Aliment Pharmacol Ther 2010; 32: 14–28 Summary Background  Novel, directly acting anti‐viral agents, also named ‘specifically targeted anti‐viral therapy for…”
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Fatigue crack growth versus plastic CTOD in the 304L stainless steel by Antunes, F.V., Ferreira, M.S.C., Branco, R., Prates, P., Gardin, C., Sarrazin-Baudoux, C.

“…•A fatigue crack growth model is proposed based on plastic CTOD.•The effect of stress state was predicted qualitatively.•The effect of stress ratio was…”
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The efficacy and safety of direct acting antiviral treatment and clinical significance of drug–drug interactions in elderly patients with chronic hepatitis C virus infection by Vermehren, J., Peiffer, K.‐H., Welsch, C., Grammatikos, G., Welker, M.‐W., Weiler, N., Zeuzem, S., Welzel, T. M., Sarrazin, C.

“…Summary Background Direct antiviral therapies for chronic hepatitis C virus (HCV) infection have expanded treatment options for neglected patient populations,…”
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Sand Mineralogy Within the Bagnold Dunes, Gale Crater, as Observed In Situ and From Orbit by Rampe, E. B., Lapotre, M. G. A., Bristow, T. F., Arvidson, R. E., Morris, R. V., Achilles, C. N., Weitz, C., Blake, D. F., Ming, D. W., Morrison, S. M., Vaniman, D. T., Chipera, S. J., Downs, R. T., Grotzinger, J. P., Hazen, R. M., Peretyazhko, T. S., Sutter, B., Tu, V., Yen, A. S., Horgan, B., Castle, N., Craig, P. I., Des Marais, D. J., Farmer, J., Gellert, R., McAdam, A. C., Morookian, J. M., Sarrazin, P. C., Treiman, A. H.

“…Curiosity investigated active eolian sands near linear dunes during Phase 2 of the Bagnold Dunes campaign in Gale crater, Mars. Ogunquit Beach, a sample…”
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Impact of HBV genotype and mutations on HBV DNA and qHBsAg levels in patients with HBeAg‐negative chronic HBV infection by Kuhnhenn, L., Jiang, B., Kubesch, A., Vermehren, J., Knop, V., Susser, S., Dietz, J., Carra, G., Finkelmeier, F., Grammatikos, G., Zeuzem, S., Sarrazin, C., Hildt, E., Peiffer, K.‐H.

“…Summary Background HBV DNA and quantitative (q)HBsAg levels as prognostic markers for HBV‐related disease are mostly validated in Asia and their significance…”
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No evidence of hepatitis B virus reactivation in patients with resolved infection treated with direct‐acting antivirals for hepatitis C in a large real‐world cohort by Mücke, V. T., Mücke, M. M., Peiffer, K.‐H., Weiler, N., Welzel, T. M., Sarrazin, C., Zeuzem, S., Berger, A., Vermehren, J.

“…Summary Background Hepatitis B virus (HBV) reactivation has been observed following interferon (IFN)‐based treatment in HBV/hepatitis C virus (HCV) co‐infected…”
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High efficacy of sofosbuvir/velpatasvir and impact of baseline resistance‐associated substitutions in hepatitis C genotype 3 infection by von Felden, J., Vermehren, J., Ingiliz, P., Mauss, S., Lutz, T., Simon, K. G., Busch, H. W., Baumgarten, A., Schewe, K., Hueppe, D., Boesecke, C., Rockstroh, J. K., Daeumer, M., Luebke, N., Timm, J., Schulze zur Wiesch, J., Sarrazin, C., Christensen, S.

“…Summary Background Twelve weeks of the pangenotypic direct‐acting antiviral (DAA) combination sofosbuvir/velpatasvir (SOF/VEL) was highly efficient in patients…”
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Acoustic radiation force impulse imaging for non-invasive assessment of liver fibrosis in chronic hepatitis B by Friedrich-Rust, M., Buggisch, P., de Knegt, R. J., Dries, V., Shi, Y., Matschenz, K., Schneider, M. D., Herrmann, E., Petersen, J., Schulze, F., Zeuzem, S., Sarrazin, C.

“…Summary Acoustic radiation force impulse (ARFI) imaging is a novel ultrasound‐based elastography method that is integrated in a conventional ultrasound…”
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The macrophage activation marker CD163 is associated with IL28B genotype and hepatic inflammation in chronic hepatitis C virus infected patients by Dultz, G., Gerber, L., Zeuzem, S., Sarrazin, C., Waidmann, O.

“…Summary Recent data highlighted the association of the macrophage activation marker CD163 with histological inflammation and fibrosis in chronic hepatitis C…”
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Expert opinion on the treatment of patients with chronic hepatitis C by Zeuzem, S., Berg, T., Moeller, B., Hinrichsen, H., Mauss, S., Wedemeyer, H., Sarrazin, C., Hueppe, D., Zehnter, E., Manns, M. P.

“…The current preferred treatment for patients with hepatitis C virus (HCV) is combination therapy consisting of pegylated interferon alfa and ribavirin (RBV)…”
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Real‐world experience with the all‐oral, interferon‐free regimen of ombitasvir/paritaprevir/ritonavir and dasabuvir for the treatment of chronic hepatitis C virus infection in the German Hepatitis C Registry by Welzel, T. M., Hinrichsen, H., Sarrazin, C., Buggisch, P., Baumgarten, A., Christensen, S., Berg, T., Mauss, S., Teuber, G., Stein, K., Deterding, K., Bömmel, F., Heyne, R., John, C., Zimmermann, T., Lutz, T., Schott, E., Hettinger, J., Kleine, H., König, B., Hüppe, D., Wedemeyer, H.

“…Summary Real‐world studies are relevant to complement clinical trials on novel antiviral therapies against chronic hepatitis C; however, clinical practice data…”
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Some critical aspects of low rate fatigue crack propagation in metallic materials by Petit, Jean, Sarrazin-Baudoux, C.

“…This paper proposes an overview of some critical aspects of fatigue crack propagation in metallic materials mainly concentrated on the near-threshold domain…”
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Numerical prediction of fatigue threshold of metallic materials in vacuum by Antunes, F.V., Prates, P.A., Camas, D., Sarrazin-Baudoux, C., Gardin, C.

“…•A numerical procedure was developed to predict effective fatigue threshold.•The numerical predictions are double of the experimental values.•The difference…”
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Real‐world use, effectiveness and safety of anti‐viral treatment in chronic hepatitis C genotype 3 infection by Cornberg, M., Petersen, J., Schober, A., Mauss, S., Böker, K. H. W., Link, R., Günther, R., Serfert, Y., Pfeiffer‐Vornkahl, H., Manns, M. P., Sarrazin, C., Hüppe, D., Berg, T., Niederau, C.

“…Summary Background Treatment of chronic hepatitis C genotype 3 (GT3) is more challenging compared with other genotypes. Since 2014, several new treatment…”
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Letter: impact of HBV genotypes and PC/BCP mutations on serum HBsAg levels in Chinese HBeAg negative patients—Authors′ reply by Kuhnhenn, L., Jiang, B., Kubesch, A., Zeuzem, S., Sarrazin, C., Hildt, E., Peffer, K.‐H.

“…Linked Content This article is linked to Kuhnhenn et al and Chen et al papers. To view these articles visit https://doi.org/10.1111/apt.14636 and…”
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Letter: telaprevir triple therapy in chronic hepatitis C genotype 1 patients receiving haemodialysis by Wiegand, J., Maasoumy, B., Buggisch, P., Buslau, A., Schiefke, I., Berg, T., Wedemeyer, H., Sarrazin, C., Hinrichsen, H.

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Editorial: genotype 3 HCV—who still needs ribavirin in a pan‐genotypic era? Authors’ reply by Felden, J., Vermehren, J., Schulze zur Wiesch, J., Sarrazin, C., Christensen, S.

“…Linked Content This article is linked to von Felden et al and Sadler papers. To view these articles visit https://doi.org/10.1111/apt.14592 and…”
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Editorial: HBsAg serum levels in HBeAg‐negative chronic HBV infection—is it a matter of genotype? Authors’ reply by Kuhnhenn, L., Jiang, B., Kubesch, A., Zeuzem, S., Sarrazin, C., Hildt, E., Peiffer, K.‐H.

“…Linked Content This article is linked to Kuhnhenn et al and Alexopoulou and Karayiannis papers. To view these articles visit https://doi.org/10.1111/apt.14636…”
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