Search Results - "Sarode, Ashish L."

Hot melt extrusion (HME) for amorphous solid dispersions: Predictive tools for processing and impact of drug–polymer interactions on supersaturation by Sarode, Ashish L., Sandhu, Harpreet, Shah, Navnit, Malick, Waseem, Zia, Hossein

“…The processing parameters for HME have been evaluated and the impact of solid state intermolecular drug–polymer interactions on supersaturation has been…”
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Supersaturation, nucleation, and crystal growth during single- and biphasic dissolution of amorphous solid dispersions: Polymer effects and implications for oral bioavailability enhancement of poorly water soluble drugs by Sarode, Ashish L., Wang, Peng, Obara, Sakae, Worthen, David R.

“…[Display omitted] The influence of polymers on the dissolution, supersaturation, crystallization, and partitioning of poorly water soluble compounds in…”
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Hot Melt Extrusion for Amorphous Solid Dispersions: Temperature and Moisture Activated Drug–Polymer Interactions for Enhanced Stability by Sarode, Ashish L, Sandhu, Harpreet, Shah, Navnit, Malick, Waseem, Zia, Hossein

“…Hot melt extrudates (HMEs) of indomethacin (IND) with Eudragit EPO and Kollidon VA 64 and those of itraconazole (ITZ) with HPMCAS-LF and Kollidon VA 64 were…”
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Stability assessment of hypromellose acetate succinate (HPMCAS) NF for application in hot melt extrusion (HME) by Sarode, Ashish L., Obara, Sakae, Tanno, Fumie K., Sandhu, Harpreet, Iyer, Raman, Shah, Navnit

“…•Stability of HPMCAS polymer was investigated for hot melt extrusion processing.•Acetic and succinic acid release was dependent on processing temperature and…”
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Hydroxypropyl cellulose stabilizes amorphous solid dispersions of the poorly water soluble drug felodipine by Sarode, Ashish L., Malekar, Swapnil A., Cote, Catherine, Worthen, David R.

“…•ASDs of a poorly water soluble drug felodipine were prepared using HPC-SSL and PVP-VA.•Stability of these ASDs at various temperatures and humidity conditions…”
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The Localization of Phenolic Compounds in Liposomal Bilayers and Their Effects on Surface Characteristics and Colloidal Stability by Malekar, Swapnil A., Sarode, Ashish L., Bach, Alvin C., Worthen, David R.

“…The interactions with and effects of five chemically distinct, bioactive phenolic compounds on the lipid bilayers of model dipalmitoylphosphatidylcholine…”
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Radio Frequency-Activated Nanoliposomes for Controlled Combination Drug Delivery by Malekar, Swapnil A., Sarode, Ashish L., Bach, Alvin C., Bose, Arijit, Bothun, Geoffrey, Worthen, David R.

“…This work was conducted in order to design, characterize, and evaluate stable liposomes containing the hydrophobic drug raloxifene HCl (RAL) and hydrophilic…”
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