Search Results - "Sarmiere, Patrick D."

The Evaluation of Magnesium Chloride within a Polyethylene Glycol Formulation in a Porcine Model of Acute Spinal Cord Injury by Streijger, Femke, Lee, Jae H T, Manouchehri, Neda, Okon, Elena B, Tigchelaar, Seth, Anderson, Lisa M, Dekaban, Greg A, Rudko, David A, Menon, Ravi S, Iaci, Jennifer F, Button, Donald C, Vecchione, Andrea M, Konovalov, Andrey, Sarmiere, Patrick D, Ung, Chi, Caggiano, Anthony O, Kwon, Brian K

“…A porcine model of spinal cord injury (SCI) was used to evaluate the neuroprotective effects of magnesium chloride (MgCl ) within a polyethylene glycol (PEG)…”
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The Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ by Sarmiere, Patrick D, Weigle, Cecile M, Tamkun, Michael M

“…The Kv2.1 delayed-rectifier K+ channel regulates membrane excitability in hippocampal neurons where it targets to dynamic cell surface clusters on the soma and…”
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Brain-Derived Neurotrophic Factor Regulation of Retinal Growth Cone Filopodial Dynamics Is Mediated through Actin Depolymerizing Factor/Cofilin by Gehler, Scott, Shaw, Alisa E, Sarmiere, Patrick D, Bamburg, James R, Letourneau, Paul C

“…The molecular mechanisms by which neurotrophins regulate growth cone motility are not well understood. This study investigated the signaling involved in…”
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RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases by Germain, Noelle D., Chung, Wendy K., Sarmiere, Patrick D.

“…Advances in genome sequencing have greatly facilitated the identification of genomic variants underlying rare neurodevelopmental and neurodegenerative…”
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Statins decrease chondroitin sulfate proteoglycan expression and acute astrocyte activation in central nervous system injury by Holmberg, Eric, Zhang, Shu-xin, Sarmiere, Patrick D., Kluge, Bridget R., White, Jason T., Doolen, Suzanne

“…Statins elicit numerous favorable effects on central nervous system (CNS) injury, including inhibition of the rhoA/ROCK pathway. In the present study, we show…”
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Regulation of the neuronal actin cytoskeleton by ADF/cofilin by Sarmiere, Patrick D., Bamburg, James R.

“…Actin and microtubules are major cytoskeletal elements of most cells including neurons. In order for a cell to move and change shape, its cytoskeleton must…”
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Nerve Growth Factor-Dependent Activation of NF-kappa B Contributes to Survival of Sympathetic Neurons by Maggirwar, Sanjay B, Sarmiere, Patrick D, Dewhurst, Stephen, Freeman, Robert S

“…Neurotrophins activate multiple signaling pathways in neurons. However, the precise roles of these signaling molecules in cell survival are not well…”
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LIM kinase 1, a key regulator of actin dynamics, is widely expressed in embryonic and adult tissues by Foletta, Victoria C, Moussi, Nathalie, Sarmiere, Patrick D, Bamburg, James R, Bernard, Ora

“…The expression of endogenous LIM kinase 1 (LIMK1) protein was investigated in embryonic and adult mice using a rat monoclonal antibody (mAb), which recognizes…”
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SM-20 Is a Novel Mitochondrial Protein That Causes Caspase-dependent Cell Death in Nerve Growth Factor-dependent Neurons by Lipscomb, Elizabeth A., Sarmiere, Patrick D., Freeman, Robert S.

“…Sympathetic neurons undergo protein synthesis-dependent apoptosis when deprived of nerve growth factor (NGF). Expression of SM-20 is up-regulated in…”
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Efficient Salmonella entry requires activity cycles of host ADF and cofilin by Dai, Shipan, Sarmiere, Patrick D, Wiggan, O’Neil, Bamburg, James R, Zhou, Daoguo

“…Summary Entry of Salmonella into mammalian cells is strictly dependent on the reorganization of actin cytoskeleton induced by a panel of Salmonella type III…”
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Head, Neck, and Spines: A Role for LIMK-1 in the Hippocampus by Sarmiere, Patrick D., Bamburg, James R.

“…LIM kinase 1 regulates actin filament dynamics through inhibition of ADF/cofilins. Surprisingly, nervous system development in LIM kinase 1 knockout mice is…”
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Expression of the SM‐20 Gene Promotes Death in Nerve Growth Factor‐Dependent Sympathetic Neurons by Lipscomb, Elizabeth A., Sarmiere, Patrick D., Crowder, Robert J., Freeman, Robert S.

“…: Sympathetic neurons undergo apoptosis when deprived of nerve growth factor (NGF). Inhibitors of RNA or protein synthesis block this death, suggesting that…”
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The Kv2.1 K.sup.+ .sup.channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ by Sarmiere, Patrick D, Weigle, Cecile M, Tamkun, Michael M

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Head, Neck, and Spines by Sarmiere, Patrick D., Bamburg, James R.

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Analysis of the NF-κB and PI 3-Kinase/Akt Survival Pathways in Nerve Growth Factor-Dependent Neurons by Sarmiere, Patrick D., Freeman, Robert S.

“…Nerve growth factor (NGF) readdition to NGF-deprived neurons can halt Jun N-terminal kinase (JNK) activation, cytochrome c release, and cell death through…”
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The Kv2.1 K super(+ )channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ by Sarmiere, Patrick D, Weigle, Cecile M, Tamkun, Michael M

“…Background The Kv2.1 delayed-rectifier K super(+ )channel regulates membrane excitability in hippocampal neurons where it targets to dynamic cell surface…”
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The role of nuclear factor kappa B in the survival of nerve growth factor-dependent sympathetic neurons by Sarmiere, Patrick D

“…Sympathetic neurons undergo cell death in the absence of nerve growth factor (NGF) yet the survival-promoting mechanisms activated by NGF are not fully…”
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