Search Results - "Sarmento, Ana Bela"

Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance by Alves, Raquel, Gonçalves, Ana Cristina, Rutella, Sergio, Almeida, António M., De Las Rivas, Javier, Trougakos, Ioannis P., Sarmento Ribeiro, Ana Bela

“…Resistance to targeted therapies is a complex and multifactorial process that culminates in the selection of a cancer clone with the ability to evade…”
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DNA Methylation Is Correlated with Oxidative Stress in Myelodysplastic Syndrome—Relevance as Complementary Prognostic Biomarkers by Gonçalves, Ana Cristina, Alves, Raquel, Baldeiras, Inês, Marques, Bárbara, Oliveiros, Bárbara, Pereira, Amélia, Nascimento Costa, José Manuel, Cortesão, Emília, Mota Vieira, Luisa, Sarmento Ribeiro, Ana Bela

“…Oxidative stress and abnormal DNA methylation have been implicated in cancer, including myelodysplastic syndromes (MDSs). This fact leads us to investigate…”
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Bone marrow follicular‐like T cells in monoclonal gammopathies by Silva, Ana, Silva, Sandra, Silva, Isabel, Santos, Susana, Laranjeira, Paula, Geraldes, Catarina, Silva, Helena, Sarmento‐Ribeiro, Ana Bela, Nascimento, Telma, Domingues, Pedro, Paiva, Artur

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CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukemia: frequency, phenotype and association with disease progression by Rodrigues, Cristiana, Laranjeira, Paula, Pinho, Aryane, Silva, Isabel, Silva, Sandra, Coucelo, Margarida, Oliveira, Ana Catarina, Simões, Ana Teresa, Damásio, Inês, Silva, Helena Matos, Urbano, Mafalda, Sarmento-Ribeiro, Ana Bela, Geraldes, Catarina, Domingues, M Rosário, Almeida, Julia, Criado, Ignacio, Orfao, Alberto, Paiva, Artur

“…In monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and…”
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Epithelial‐mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer by Domingues, Cátia Sofia da Costa, Serambeque, Beatriz Prazeres, Laranjo Cândido, Mafalda Sofia, Marto, Carlos Miguel Machado, Veiga, Francisco José de Baptista, Sarmento Antunes Cruz Ribeiro, Ana Bela, Figueiras, Ana Rita Ramalho, Botelho, Maria Filomena Roque, Dourado, Marília de Assunção Rodrigues Ferreira

“…Background Head and neck cancer is the sixth most common cancer worldwide, with oral squamous cell carcinoma (OSCC) being the most representative type. OSCC is…”
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CD43 and CD49d from the B‐Cell Chronic Lymphoproliferative Disorders Diagnostic Panel Are Useful to Detect Erythroid Dysplasia by Oliveira, Melissa, Laranjeira, Paula, Fortuna, Manuela, Bártolo, Rui, Ribeiro, André, Santos, Mónica, Cortesão, Emília, Marques, Gilberto, Sarmento‐Ribeiro, Ana Bela, Vitória, Helena, Ribeiro, Letícia, Paiva, Artur

“…Background Despite bone marrow (BM) immunophenotyping by flow cytometry has progressively been recognized as an important tool for the diagnosis of…”
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PB1822: INHIBITION OF THE DNA DAMAGE RESPONSE: A POSSIBLE NEW ROUTE IN ACUTE MYELOBLASTIC LEUKEMIA TREATMENT by Lapa, Beatriz, Costa, Maria Inês, Jorge, Joana, Alves, Raquel, Sarmento‐Ribeiro, Ana Bela, Gonçalves, Ana Cristina

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P659: BUPARLISIB A PROMISING THERAPEUTIC APPROACH IN CHRONIC MYELOID LEUKEMIA RESISTANT TO IMATINIB by Alves, Raquel, Silva, Inês, Inês Costa, Maria, Lapa, Beatriz, Jorge, Joana, Cristina Gonçalves, Ana, Bela Sarmento‐Ribeiro, Ana

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PB1841: NUCLEOLIN INTERACTS WITH NUCLEOPHOSMIN AS A PREDICTOR OF PROGNOSIS IN ACUTE MYELOBLASTIC LEUKEMIA by Pereira, Marta, Silva, Isabel, Paiva, Artur, Sarmento‐Ribeiro, Ana‐Bela, Moreira, João‐Nuno

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PB1910: TELAGLENASTAT (CB‐839) IN MONOTHERAPY AND IN COMBINATION WITH EPIGENETIC MODULATORS OR IBRUTINIB INDUCES CELL DEATH IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS by Jorge, Joana, Santiago, Hugo, Constantino, Beatriz, Costa, Maria Inês, Lapa, Beatriz, Alves, Raquel, Gonçalves, Ana Cristina, Sarmento‐Ribeiro, Ana Bela

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P841: MOLECULAR MECHANISMS OF RESISTANCE TO IMMUNOMODULATORS IN MULTIPLE MYELOMA: AN IN VITRO STUDY by Alves, Raquel, Sofia Almeida, Ana, Inês Costa, Maria, Lapa, Beatriz, Jorge, Joana, Cristina Gonçalves, Ana, Geraldes, Catarina, Bela Sarmento‐Ribeiro, Ana

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PB1719: NIRAPARIB IN B‐CELL LYMPHOID MALIGNANCIES: EXPLORING SYNTHETIC LETHALITY AS TARGET FOR THERAPY by Lapa, Beatriz, Portelinha, Ana Patrícia, Costa, Maria Inês, Jorge, Joana, Alves, Raquel, Sarmento‐Ribeiro, Ana Bela, Gonçalves, Ana Cristina

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Effects of X-radiation on lung cancer cells: the interplay between oxidative stress and P53 levels by Mendes, Fernando, Sales, Tiago, Domingues, Cátia, Schugk, Susann, Abrantes, Ana Margarida, Gonçalves, Ana Cristina, Teixo, Ricardo, Silva, Rita, Casalta-Lopes, João, Rocha, Clara, Laranjo, Mafalda, Simões, Paulo César, Sarmento Ribeiro, Ana Bela, Botelho, Maria Filomena, Rosa, Manuel Santos

“…Lung cancer (LC) ranks as the most prevalent and deadliest cause of cancer death worldwide. Treatment options include surgery, chemotherapy and/or…”
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Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis by Gonçalves, Ana Cristina, Alves, Raquel, Baldeiras, Inês, Cortesão, Emília, Carda, José Pedro, Branco, Claudia C., Oliveiros, Bárbara, Loureiro, Luísa, Pereira, Amélia, Nascimento Costa, José Manuel, Sarmento‐Ribeiro, Ana Bela, Mota‐Vieira, Luisa

“…Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) share common features: elevated oxidative stress, DNA repair deficiency, and aberrant DNA…”
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Zinc: From Biological Functions to Therapeutic Potential by Costa, Maria Inês, Sarmento-Ribeiro, Ana Bela, Gonçalves, Ana Cristina

“…The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control intercellular communication and intracellular events that maintain…”
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The multi-factorial nature of clinical multidrug resistance in cancer by Assaraf, Yehuda G., Brozovic, Anamaria, Gonçalves, Ana Cristina, Jurkovicova, Dana, Linē, Aija, Machuqueiro, Miguel, Saponara, Simona, Sarmento-Ribeiro, Ana Bela, Xavier, Cristina P.R., Vasconcelos, M. Helena

“…Curative cancer therapy remains a major challenge particularly in cancers displaying multidrug resistance (MDR). The MDR phenotype is characterized by…”
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Cancer immunotherapy resistance based on immune checkpoints inhibitors: Targets, biomarkers, and remedies by Pérez-Ruiz, Elisabeth, Melero, Ignacio, Kopecka, Joanna, Sarmento-Ribeiro, Ana Bela, García-Aranda, Marilina, De Las Rivas, Javier

“…Cancer is one of the main public health problems in the world. Systemic therapies such as chemotherapy and more recently target therapies as well as…”
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The emergence of drug resistance to targeted cancer therapies: Clinical evidence by Sarmento-Ribeiro, Ana Bela, Scorilas, Andreas, Gonçalves, Ana Cristina, Efferth, Thomas, Trougakos, Ioannis P.

“…For many decades classical anti-tumor therapies included chemotherapy, radiation and surgery; however, in the last two decades, following the identification of…”
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Advancements in Biomarkers and Molecular Targets in Hematological Neoplasias by Gonçalves, Ana Cristina, Alves, Raquel, Sarmento-Ribeiro, Ana Bela

“…Hematological neoplasias are among the most common cancers worldwide, and the number of new cases has been on the rise since 1990, reaching 1 [...]…”
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Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies by Jorge, Joana, Neves, Joana, Alves, Raquel, Geraldes, Catarina, Gonçalves, Ana Cristina, Sarmento-Ribeiro, Ana Bela

“…Lymphoid malignancies are a group of highly heterogeneous diseases frequently associated with constitutive activation of the nuclear factor kappa B (NF-κB)…”
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