Search Results - "Sarkisian, Christopher J"
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1
The transcriptional repressor Snail promotes mammary tumor recurrence
Published in Cancer cell (01-09-2005)“…Breast cancer recurrence is a fundamental clinical manifestation of tumor progression and represents the principal cause of death from this disease. Using a…”
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Journal Article -
2
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
Published in Cancer cell (01-12-2002)“…To determine the impact of tumor progression on the reversibility of Neu-induced tumorigenesis, we have used the tetracycline regulatory system to…”
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Journal Article -
3
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
Published in Nature cell biology (01-05-2007)“…Activating Ras mutations can induce either proliferation or senescence depending on the cellular context. To determine whether Ras activation has…”
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Journal Article -
4
Salt Effects on Ionization Equilibria of Histidines in Myoglobin
Published in Biophysical journal (01-09-2000)“…The salt dependence of histidine p K a values in sperm whale and horse myoglobin and in histidine-containing peptides was measured by 1H-NMR spectroscopy…”
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Journal Article -
5
Impaired DNA Damage Response in Cells Expressing an Exon 11-Deleted Murine Brca1 Variant That Localizes to Nuclear Foci
Published in Molecular and Cellular Biology (01-06-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Analysis of Murine Brca2 Reveals Conservation of Protein-Protein Interactions but Differences in Nuclear Localization Signals
Published in The Journal of biological chemistry (05-10-2001)“…In this report, we have analyzed the protein encoded by the murine Brca2 locus. We find that murine Brca2 shares multiple properties with human BRCA2 including…”
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Investigation of the in vivo stress response to oncogenic mutation and tumor suppressor inactivation in mammary carcinogenesis
Published 01-01-2004“…Breast cancer is believed to arise from the cumulative mutation of oncogenes and tumor suppressors within a small number of precursor cells within the mammary…”
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Dissertation -
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Identification of a Novel AP-2 Consensus DNA Binding Site
Published in Biochemical and biophysical research communications (04-02-1998)“…Activator Protein (AP)-2 is a transcription factor that is required for mouse development. AP-2 activates expression of positive and negative growth regulators…”
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Journal Article