The association between follicular size at the time of spontaneous rupture and pregnancy rates in clomiphene citrate treated PCOS patients in coit cycles

Abstract Objective: To investigate the follicular size at spontaneous rupture on pregnancy rate in patients with polycystic ovary syndrome (PCOS) undergoing clomiphene citrate (CC) ovulation. Design: Cross-sectional study. Patients and methods: One hundred and four women with ovulatory cycles after...

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Published in:	Gynecological endocrinology Vol. 31; no. 5; pp. 392 - 395
Main Authors:	Portocarrero-Sanchez, Carlos, Gomes-Sobrinho, David Barreira, Nakagawa, Hitomi Miura, Silva, Adelino Amaral, Carvalho, Bruno Ramalho de, Sarkis, Nathália Travassos, Peraçoli, José Carlos, Cardoso, Maria Teresinha de Oliveira
Format:	Journal Article
Language:	English
Published:	England Informa UK Ltd 01-05-2015 Informa Healthcare
Subjects:	Adult Anovulatory infertility Clomiphene - therapeutic use clomiphene citrate Cross-Sectional Studies Estrogen Antagonists - therapeutic use Female follicular size Humans Infertility, Female - drug therapy Infertility, Female - etiology Organ Size Ovarian Follicle - diagnostic imaging Ovarian Follicle - growth & development Ovulation Ovulation Induction PCOS Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - drug therapy Pregnancy Pregnancy Rate Ultrasonography follicular size Anovulatory infertility clomiphene citrate PCOS pregnancy rate
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Summary:	Abstract Objective: To investigate the follicular size at spontaneous rupture on pregnancy rate in patients with polycystic ovary syndrome (PCOS) undergoing clomiphene citrate (CC) ovulation. Design: Cross-sectional study. Patients and methods: One hundred and four women with ovulatory cycles after use of CC followed by ultrasound to determine the follicle size at the time of rupture, which was subsequently correlated with the occurrence of pregnancy or not in coit cycles. Results: In the group of follicular rupture at a mean diameter 25 mm (n = 54), pregnancy rate was 35.1% and when follicular rupture occurred at a mean diameter >25 mm (n = 50), it was 34% (p > 0.05). When different diameters at follicular rupture were randomly correlated with the pregnancy rate, there was no significant difference. Conclusion: Our data suggest that the occurrence of pregnancy after ovulation induction with CC in women with PCOS is not associated with follicle size at the time of rupture.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0951-3590 1473-0766
DOI:	10.3109/09513590.2015.1006186