Search Results - "Sarkar, Surajit"

Tissue-Specific Upregulation of Drosophila Insulin Receptor (InR) Mitigates Poly(Q)-Mediated Neurotoxicity by Restoration of Cellular Transcription Machinery by Raj, Kritika, Sarkar, Surajit

“…Polyglutamine [poly(Q)] disorders are a class of trinucleotide repeat expansion neurodegenerative disorders which are dominantly inherited and progressively…”
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Polydiacetylene‑N‑1-Hexadecyl Imidazole Mixed Film and Its Application toward the Sensing of Volatile Organic Compounds, Gasoline, and Pollution Level in Car Exhaust by Suklabaidya, Sudip, Chakraborty, Sekhar, Sarkar, Surajit, Paul, Ripa, Banik, Hritinava, Chakraborty, Ankita, Bhattacharjee, Debajyoti, Majumdar, Swapan, Hussain, Syed A

“…Polydiacetylenes have gained increasing attention as promising smart materials owing to their brilliant blue-to-red color transition in response to various…”
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Transactivation Domain of Human c-Myc Is Essential to Alleviate Poly(Q)-Mediated Neurotoxicity in Drosophila Disease Models by Raj, Kritika, Sarkar, Surajit

“…Polyglutamine (poly(Q)) disorders, such as Huntington’s disease (HD) and spinocerebellar ataxias, represent a group of neurological disorders which arise due…”
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Design and synthesis of bis-coumarinyl methanes from 4-hydroxy-coumarin and aldehydes catalysed by Amberlyst 15 via dual C–C coupling: introducing coumarin based thin film organic nano-materials for memory devices by Rudra Paul, Abhijit, Sarkar, Surajit, Hossain, Jewel, Hussain, Syed Arshad, Majumdar, Swapan

“…An efficient one pot synthesis of various bis-coumarinyl methane derivatives was investigated by condensing a series of aldehydes with 4-hydroxy coumarin in…”
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Noncytotoxic WORM Memory Using Lysozyme with Ultrahigh Stability for Transient and Sustainable Electronics Applications by Banik, Hritinava, Sarkar, Surajit, Bhattacharjee, Debajyoti, Malhotra, Akshit, Chauhan, Ashwini, Hussain, Syed Arshad

“…Biocompatibility and transient nature of electronic devices have been the matter of attention in recent times due to their immense potential for sustainable…”
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Drosophila Myc, a novel modifier suppresses the poly(Q) toxicity by modulating the level of CREB binding protein and histone acetylation by Singh, M. Dhruba, Raj, Kritika, Sarkar, Surajit

“…Abstract Polyglutamine or poly(Q) disorders are dominantly inherited neurodegenerative diseases characterised by progressive loss of neurons in cerebellum,…”
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Financial analysis for custom hire business of mechanical rice transplanter in Bangladesh by Surajit Sarkar, Md. Samiul Basir, Muhammad Ashik E Rabbani, Md. Mosharraf Hossain, Md. Monjurul Alam

“…This study was conducted to analyze the financial parameters of a mechanical rice transplanter operation for local service providers and entrepreneurs with…”
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Myc functions downstream of InR and their concurrent upregulation additively restricts pathogenesis of human poly(Q) disorders in Drosophila disease models by Tandon, Shweta, Sarkar, Surajit

“…Human polyglutamine [poly(Q)] disorders are caused by abnormal expansion of CAG repeats in one gene (disease specific), yet a plethora of cellular pathways are…”
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Glipizide ameliorates human poly(Q) mediated neurotoxicity by upregulating insulin signalling in Drosophila disease models by Tandon, Shweta, Sarkar, Surajit

“…Increasing reports suggest insulin signalling pathway as a putative drug target against polyglutamine [poly(Q)] disorders, such as Huntington's disease (HD),…”
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Targeted upregulation of dMyc restricts JNK-mediated degeneration of dopaminergic neurons in the paraquat-induced Parkinson’s disease model of Drosophila by Pragati, Sarkar, Surajit

“…Parkinson’s disease is the second most common neurodegenerative disease characterized by the loss of dopaminergic neurons in the brain. Parkinson’s disease has…”
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The S6k/4E-BP mediated growth promoting sub-pathway of insulin signalling cascade is essential to restrict pathogenesis of poly(Q) disorders in Drosophila by Tandon, Shweta, Sarkar, Surajit

“…Human neurodegenerative polyglutamine [poly(Q)] disorders, such as Huntington's disease (HD) and spinocerebellar ataxias (SCA), are characterised by an…”
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Glutamine stimulates the S6K/4E-BP branch of insulin signalling pathway to mitigate human poly(Q) disorders in Drosophila disease models by Tandon, Shweta, Sarkar, Surajit

“…Since, the S6K/4E-BP sub-pathway can be stimulated by various amino acids; we extended our investigation to examine if oral feeding of amino acids delivers…”
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Downregulation of glob1 suppresses pathogenesis of human neuronal tauopathies in Drosophila by regulating tau phosphorylation and ROS generation by Nisha, Sarkar, Surajit

“…Human tauopathies represent a group of neurodegenerative disorders, characterized by abnormal hyperphosphorylation and aggregation of tau protein, which…”
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Age dependent trans-cellular propagation of human tau aggregates in Drosophila disease models by Aqsa, Sarkar, Surajit

“…•Human tau aggregates migrate trans-cellularly in aging adult Drosophila.•Tau hyperphosphorylation appears to be an important factor for trans-cellular…”
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Reinstated Activity of Human Tau-induced Enhanced Insulin Signaling Restricts Disease Pathogenesis by Regulating the Functioning of Kinases/Phosphatases and Tau Hyperphosphorylation in Drosophila by Pragati, Sarkar, Surajit

“…Tauopathies such as Alzheimer’s disease (AD), Frontotemporal dementia, and parkinsonism linked to chromosome 17 (FTDP-17), etc. are characterized by tau…”
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Neurofibrillary tangles mediated human neuronal tauopathies: insights from fly models by Sarkar, Surajit

“…Tauopathies represent a group of neurodegenerative disorder which are characterized by the presence of tau positive specialized argyrophilic and insoluble…”
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Shaggy functions downstream of dMyc and their concurrent downregulation confers additive rescue against tau toxicity in Drosophila by Pragati, Sarkar, Surajit

“…Neurodegenerative tauopathies such as Alzheimer's and Parkinson's diseases are characterized by hyperphosphorylation of tau protein and their subsequent…”
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Downregulation of glob1 mitigates human tau mediated neurotoxicity by restricting heterochromatin loss and elevating the autophagic response in drosophila by Nisha, Sarkar, Surajit

“…Background Human neuronal tauopathies are typically characterized by the accumulation of hyperphosphorylated tau in the forms of paired helical filaments…”
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Polyglutamine disorders: Pathogenesis and potential drug interventions by Tandon, Shweta, Aggarwal, Prerna, Sarkar, Surajit

“…Polyglutamine/poly(Q) diseases are a group nine hereditary neurodegenerative disorders caused due to abnormally expanded stretches of CAG trinucleotide in…”
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A Solar Flare Simulation Wheel for the Radiation Test Beamline at the Francis H. BurrProton Therapy Center by Cascio, E.W., Sarkar, S.

“…The design, construction and testing of a rotating energy shifter that simulates the proton energy spectrum of a solar flare event is described…”
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