Search Results - "Sarkar, Poonam"
-
1
Asprosin, a Fasting-Induced Glucogenic Protein Hormone
Published in Cell (21-04-2016)“…Hepatic glucose release into the circulation is vital for brain function and survival during periods of fasting and is modulated by an array of hormones that…”
Get full text
Journal Article -
2
Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation
Published in Nature communications (09-10-2020)“…Mutations in the skeletal muscle Ca 2+ release channel, the type 1 ryanodine receptor (RYR1), cause malignant hyperthermia susceptibility (MHS) and a…”
Get full text
Journal Article -
3
LOX upregulates FAK phosphorylation to promote metastasis in osteosarcoma
Published in Genes & diseases (01-01-2023)“…Osteosarcoma is a malignant bone tumor that commonly occurs in the pediatric population. Despite the use of chemotherapy and surgery, metastasis remains to be…”
Get full text
Journal Article -
4
Hyperoxia Disrupts Lung Lymphatic Homeostasis in Neonatal Mice
Published in Antioxidants (01-03-2023)“…Inflammation causes bronchopulmonary dysplasia (BPD), a common lung disease of preterm infants. One reason this disease lacks specific therapies is the paucity…”
Get full text
Journal Article -
5
Induction of COX-2 by acrolein in rat lung epithelial cells
Published in Molecular and cellular biochemistry (01-07-2007)“…Acrolein is a highly reactive alpha, beta-unsaturated aldehyde, and a product of lipid peroxidation reactions. Acrolein is also an environmental pollutant and…”
Get full text
Journal Article -
6
Novel lean type 2 diabetic rat model using gestational low-protein programming
Published in American journal of obstetrics and gynecology (01-04-2016)“…Background Type 2 diabetes (T2D) in lean individuals is not well studied and up to 26% of diabetes occurs in these individuals. Although the cause is not well…”
Get full text
Journal Article -
7
Response of DNA damage genes in acrolein-treated lung adenocarcinoma cells
Published in Molecular and cellular biochemistry (01-01-2019)“…Acrolein is a α-β-unsaturated aldehyde and is toxic to human upon its exposure from the environment. Sources of exposure to acrolein can be from heating…”
Get full text
Journal Article -
8
Proteomic Analysis of Mouse Hypothalamus under Simulated Microgravity
Published in Neurochemical research (01-11-2008)“…Exposure to altered microgravity during space travel induces changes in the brain and these are reflected in many of the physical behavior seen in the…”
Get full text
Journal Article -
9
Echocardiography Differentiates Lethally Irradiated Whole-Body From Partial-Body Exposed Rats
Published in Frontiers in cardiovascular medicine (16-10-2018)“…Acute radiation syndrome (ARS) affects morbidity and mortality dependent on the amount of body exposed. We propose the use of echocardiography (EC) to…”
Get full text
Journal Article -
10
Proteomic Analysis of Mice Hippocampus in Simulated Microgravity Environment
Published in Journal of proteome research (01-03-2006)“…Space travel induces many deleterious effects on the flight crew due to the ‘0' g environment. The brain experiences a tremendous fluid shift, which is…”
Get full text
Journal Article -
11
Abstract 965: The role of LOX-mediated FAK phosphorylation in osteosarcoma metastasis
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Despite the use of chemotherapy and surgery, the development of metastasis remains to be the leading cause of death in patients with osteosarcoma. LOX…”
Get full text
Journal Article -
12
The bone microenvironment increases phenotypic plasticity of ER + breast cancer cells
Published in Developmental cell (19-04-2021)“…Estrogen receptor-positive (ER ) breast cancer exhibits a strong bone tropism in metastasis. How the bone microenvironment (BME) impacts ER signaling and…”
Get full text
Journal Article -
13
A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction
Published in Proceedings of the National Academy of Sciences - PNAS (08-12-2020)“…Progressive remodeling of the heart, resulting in cardiomyocyte (CM) loss and increased inflammation, fibrosis, and a progressive decrease in cardiac function,…”
Get full text
Journal Article -
14
NF-κB Blockade by NEMO Binding Domain Peptide Ameliorates Inflammation and Neurobehavioral Sequelae After Cranial Radiation Therapy in Juvenile Mice
Published in International journal of radiation oncology, biology, physics (01-04-2021)“…Cranial radiation therapy (CRT) is a common treatment for pediatric brain tumor patients. However, side effects include significant neurobehavioral dysfunction…”
Get full text
Journal Article -
15
Nanoparticle Contrast-enhanced T1-Mapping Enables Estimation of Placental Fractional Blood Volume in a Pregnant Mouse Model
Published in Scientific reports (10-12-2019)“…Non-invasive methods for estimating placental fractional blood volume (FBV) are of great interest for characterization of vascular perfusion in placentae…”
Get full text
Journal Article -
16
64: Novel lean type 2 diabetic rat model using gestational low protein programming
Published in American journal of obstetrics and gynecology (2016)Get full text
Journal Article -
17
Proteomic profiling of rat lung epithelial cells induced by acrolein
Published in Life sciences (1973) (31-07-2009)“…Acrolein is a highly toxic unsaturated aldehyde and is also an endogenous byproduct produced from lipid peroxidation. It can be formed from the breakdown of…”
Get full text
Journal Article -
18
Protective effect of quercetin on acrolein-induced COX-2 expression in lung epithelial cells
Published in Toxicological and environmental chemistry (01-05-2013)“…The purpose of this study was to determine whether quercetin can protect against acrolein-induced cyclooxygenase-2 (COX-2) expression using rat lung epithelial…”
Get full text
Journal Article -
19
Molecular and morphological characterization of somatic hybrids between Solanum tuberosum L. and S. etuberosum Lindl
Published in Plant cell, tissue and organ culture (01-11-2010)“…Interspecific potato somatic hybrids between Solanum tuberosum L. (di)haploid C-13 and 1 endosperm balance number non-tuberous wild species S. etuberosum…”
Get full text
Journal Article -
20
Activation of telomerase in BeWo cells by estrogen and 2,3,7,8- tetrachlorodibenzo-p-dioxin in co-operation with c-Myc
Published in International journal of oncology (2006)“…Telomerase activation, known to be stimulated by estrogen, is essential for cellular immortalization and trans-formation, both of which play a role in…”
Get full text
Journal Article