Search Results - "Sarkar, F. H."

Coinage metal complexes against breast cancer by Biersack, B, Ahmad, A, Sarkar, F H, Schobert, R

“…Breast cancer is still the leading cause of cancer deaths among women worldwide, and new therapies to treat this dangerous disease are desperately needed. The…”
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MicroRNA profiling of diagnostic needle aspirates from patients with pancreatic cancer by Ali, S, Saleh, H, Sethi, S, Sarkar, F H, Philip, P A

“…Background: A major challenge to the development of biomarkers for pancreatic cancer (PC) is the small amount of tissue obtained at the time of diagnosis…”
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Perspectives on medicinal properties of mangiferin by Vyas, A, Syeda, K, Ahmad, A, Padhye, S, Sarkar, F H

“…Mango tree, Mangifera indica, has been cultivated in India and several other tropical countries for centuries, and it is a good source of compound…”
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Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants by Zubair, H, Khan, H Y, Sohail, A, Azim, S, Ullah, M F, Ahmad, A, Sarkar, F H, Hadi, S M

“…Plant-derived dietary antioxidants have attracted considerable interest in recent past for their chemopreventive and cancer therapeutic abilities in animal…”
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MicroRNAs in personalized cancer therapy by Sethi, S., Ali, S., Sarkar, F.H.

“…MicroRNAs (miRNAs) are small endogenous noncoding single‐stranded RNAs. They critically regulate the post‐transcriptional activity of several key physiological…”
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Expression of microRNAs: potential molecular link between obesity, diabetes and cancer by Ali, A. S, Ali, S, Ahmad, A, Bao, B, Philip, P. A, Sarkar, F. H

“…Clinicians are routinely challenged in their management of cancer patients because of the complexities of obesity and diabetes that are often found as comorbid…”
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MI-219-zinc combination: a new paradigm in MDM2 inhibitor-based therapy by Azmi, A S, Philip, P A, Beck, F W J, Wang, Z, Banerjee, S, Wang, S, Yang, D, Sarkar, F H, Mohammad, R M

“…Zinc has a crucial role in the biology of p53 in that p53 binds to DNA through a structurally complex domain stabilized by zinc atom. The p53 negative…”
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Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein by YIWEI LI, UPADHYAY, S, BHUIYAN, M, SARKAR, F. H

“…Breast cancer is the most common cancer among American women, whereas Asian women, who consume a traditional diet high in soy products, have a relatively low…”
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Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype by Wang, Z., Ali, S., Banerjee, S., Bao, B., Li, Y., Azmi, A.S., Korc, M., Sarkar, F.H.

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Induction of apoptosis and inhibition of c-erbB-2 in MDA-MB-435 cells by genistein by Li, Y, Bhuiyan, M, Sarkar, F H

“…Breast cancer is the most common cancer and second leading cause of cancer related deaths in women in the United States. Genistein is a protein tyrosine kinase…”
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MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFβR2) in colon cancer cells by Yu, Yingjie, Kanwar, Shailender S., Patel, Bhaumik B., Oh, Phil-Sun, Nautiyal, Jyoti, Sarkar, Fazlul H., Majumdar, Adhip P.N.

“…Although microRNA-21 (miR-21) is emerging as an oncogene and has been shown to target several tumor suppressor genes, including programmed cell death 4…”
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Genistein inhibits NF-κB activation in prostate cancer cells by DAVIS, J. N, KUCUK, O, SARKAR, F. H

“…Prostate cancer is the second leading cause of cancer-related deaths in men in the United States. Epidemiological studies indicate that susceptibility to…”
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ASPP and iASPP: Implication in cancer development and progression by Li, Y, Ahmad, A, Sarkar, F H

“…The well-known guardian of genome, p53 plays critical roles in the induction of apoptosis typically upon DNA damage whereas mutant p53 containing cells are…”
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Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer by SOUBANI, Omar, ALI, Azfur S, LOGNA, Farah, ALI, Shadan, PHILIP, Philip A, SARKAR, Fazlul H

“…Membrane type-1 matrix metalloproteinase (MT1-MMP) is often activated and expressed in tumor cells with significant invasive properties, and is associated with…”
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Inhibition of prostate specific antigen expression by genistein in prostate cancer cells by Davis, J N, Muqim, N, Bhuiyan, M, Kucuk, O, Pienta, K J, Sarkar, F H

“…Recent studies have provided convincing evidence for the role of soy-isoflavones, particularly genistein, in the inhibition of prostate cancer cell growth…”
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p53 Status and Prognosis of Locally Advanced Prostatic Adenocarcinoma: a Study Based on RTOG 8610 by Grignon, David J., Sarkar, Fazlul H., Forman, Jeffrey D., Caplan, Richard, Pajak, Thomas F., Lawton, Colleen A., Hammond, Elizabeth H., Pilepich, Miljenko V., Mesic, John, Fu, Karen K., Abrams, Ross A., Shipley, William U., Cox, James D.

“…Background: The p53 tumor suppressor gene (also known as TP53) is one of the most frequently mutated genes in human cancer. Several studies have shown that p53…”
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Genistein Elicits Pleiotropic Molecular Effects on Head and Neck Cancer Cells by ALHASAN, Samir A, ARANHA, Olivia, SARKAR, Fazlul H

“…Genistein (4,5,7-trihydroxyisoflavone) has been reported to induce cell cycle arrest and apoptosis in different cancer cell lines in vitro and to show…”
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Differential sensitivity of normal and malignant breast epithelial cells to genistein is partly mediated by p21(WAF1) by Upadhyay, S, Neburi, M, Chinni, S R, Alhasan, S, Miller, F, Sarkar, F H

“…Genistein, a soy metabolite, is a potential chemopreventive agent against various types of cancer. There are several studies documenting molecular alterations…”
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Genistein induced molecular changes in a squamous cell carcinoma of the head and neck cell line by Alhasan, S A, Ensley, J F, Sarkar, F H

“…Epidemiological studies have shown lower incidence of breast and prostate cancers in Asian populations consuming a traditional diet rich in soy. Protection…”
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Perspectives on chemopreventive and therapeutic potential of curcumin analogs in medicinal chemistry by Padhye, Subhash, Chavan, Deepak, Pandey, Shubhangini, Deshpande, Jyoti, Swamy, K Venkateswara, Sarkar, Fazlul H

“…Curcumin is a natural polyphenol derived from the plant Curcuma longa, commonly called turmeric. Extensive research over past 50 years has indicated that this…”
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