Search Results - "Sarkar, Chitra"
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Surgery for Drug-Resistant Epilepsy in Children
Published in The New England journal of medicine (26-10-2017)“…In children with drug-resistant epilepsy, the rate of freedom from seizures at 1 year was higher with epilepsy surgery than with medical therapy alone. Most…”
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cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas
Published in Acta neuropathologica (01-03-2020)Get full text
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ACE2 protein expression in lung tissues of severe COVID-19 infection
Published in Scientific reports (08-03-2022)“…Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within…”
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Interface Engineering of Graphene-Supported Cu Nanoparticles Encapsulated by Mesoporous Silica for Size-Dependent Catalytic Oxidative Coupling of Aromatic Amines
Published in ACS applied materials & interfaces (27-03-2019)“…In this study, graphene nanosheet-supported ultrafine Cu nanoparticles (NPs) encapsulated with thin mesoporous silica (Cu–GO@m-SiO2) materials are fabricated…”
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MED12 is overexpressed in glioblastoma patients and serves as an oncogene by targeting the VDR/BCL6/p53 axis
Published in Cellular and molecular life sciences : CMLS (01-02-2022)“…Glioblastoma is the most life-threatening tumor of the central nervous system. Despite recent therapeutic advancements, maximum survival of glioblastoma…”
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Integration of Interfacial and Alloy Effects to Modulate Catalytic Performance of Metal–Organic-Framework-Derived Cu–Pd Nanocrystals toward Hydrogenolysis of 5‑Hydroxymethylfurfural
Published in ACS sustainable chemistry & engineering (17-06-2019)“…Selective formation of 2,5-dimethylfuran (DMF) by hydrogenolysis of lignocellulosic biomass-derived 5-hydroxymethylfurfural (HMF) is highly desirable for…”
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Loss-of-Function Mutations in Calcitonin Receptor ( CALCR ) Identify Highly Aggressive Glioblastoma with Poor Outcome
Published in Clinical cancer research (15-03-2018)“…Despite significant advances in the understanding of the biology, the prognosis of glioblastoma (GBM) remains dismal. The objective was to carry out…”
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ALDH5A1/miR-210 axis plays a key role in reprogramming cellular metabolism and has a significant correlation with glioblastoma patient survival
Published in Cancer cell international (22-07-2024)“…Glioblastoma (GBM) is the most aggressive among the tumors of the central nervous system (CNS), and has a dismal prognosis. Altered metabolism, especially the…”
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Telomerase reverse transcriptase (TERT) ‐ enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma
Published in Journal of neurochemistry (01-12-2017)“…Elevated expression of enhancer of zeste homolog 2 (EZH2), a histone H3K27 methyltransferase, was observed in gliomas harboring telomerase reverse…”
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A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme
Published in Scientific reports (26-05-2017)“…Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different…”
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Non-neoplastic disorders of the nervous system: Emerging from the shadows
Published in Indian journal of pathology & microbiology (01-05-2022)Get full text
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Current status of neuromuscular pathology: An overview with special reference to Indian Scenario
Published in Indian journal of pathology & microbiology (01-05-2022)Get full text
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Upregulation of Atypical Cadherin FAT1 Promotes an Immunosuppressive Tumor Microenvironment via TGF-β
Published in Frontiers in immunology (26-05-2022)“…FAT atypical cadherin 1 (FAT1) promotes glioblastoma (GBM) by promoting protumorigenic inflammatory cytokine expression in tumor cells. However, tumors also…”
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Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality
Published in Disease models & mechanisms (01-05-2022)“…To elucidate the molecular mechanisms that manifest lung abnormalities during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we…”
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Genetic alterations related to BRAF‐FGFR genes and dysregulated MAPK/ERK/mTOR signaling in adult pilocytic astrocytoma
Published in Brain pathology (Zurich, Switzerland) (01-09-2017)“…Pilocytic astrocytomas occur rarely in adults and show aggressive tumor behavior. However, their underlying molecular‐genetic events are largely…”
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World Health Organization Classification of Tumors of the Central Nervous System 5th Edition (WHO CNS5): What's new?
Published in Indian journal of pathology & microbiology (01-05-2022)“…The latest fifth edition of the World Health Organization classification of central nervous system tumors (WHO CNS5) has been built on the prior WHO 2016…”
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Hypoxia-inducible miR-196a modulates glioblastoma cell proliferation and migration through complex regulation of NRAS
Published in Cellular oncology (Dordrecht) (01-04-2021)“…Background Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in humans. Hypoxia has been correlated with the aggressive form of glial…”
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Primary CNS vasculitis (PCNSV): a cohort study
Published in Scientific reports (05-08-2022)“…Primary CNS Vasculitis (PCNSV) is a rare inflammatory disorder affecting the blood vessels of the central nervous system. Patients present with a combination…”
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Pediatric-type diffuse low grade gliomas: Histomolecular profile and practical approach to their integrated diagnosis according to the WHO CNS5 classification
Published in Indian journal of pathology & microbiology (01-05-2022)“…Low-grade gliomas are the most common primary central nervous system (CNS) neoplasms in the pediatric age group. The majority of these tumors are…”
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