Myeloperoxydase Expression in The Pathogenesis of Nasal Polyps

Nasal polyps are benign mucosal protrusions that expand into the nasal cavity. There are no any etiological factors that may explain the pathogenesis of nasal polyps but currently inflammation continues to be the major factor. As a result of inflammation, neutrophils become activated and migrate to...

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Bibliographic Details
Published in:	Indian journal of otolaryngology, and head, and neck surgery Vol. 63; no. 3; pp. 260 - 263
Main Authors:	Sarisoy, Burcin A., Eken, Mehmet, Oktay, Alev Z., Paksoy, Mustafa, Sanli, Arif
Format:	Journal Article
Language:	English
Published:	India Springer-Verlag 01-07-2011
Subjects:	Head and Neck Surgery Medicine Medicine & Public Health Original Original Article Otorhinolaryngology Free oxygen radicals Myeloperoxidase Inflammation Nasal polyps
Online Access:	Get full text
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Summary:	Nasal polyps are benign mucosal protrusions that expand into the nasal cavity. There are no any etiological factors that may explain the pathogenesis of nasal polyps but currently inflammation continues to be the major factor. As a result of inflammation, neutrophils become activated and migrate to the inflammatory area and form their bactericidal effects by producing free oxygen radicals. The objective of our study is to investigate the expression of myeloperoxydase enzyme, which is usually an indicator of leukocyte infiltration and is responsible in the formation of free oxygen radicals in polyp tissues and to determine its role in the pathogenesis of nasal polyps.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2231-3796 0973-7707
DOI:	10.1007/s12070-011-0165-2