Search Results - "Sarioglu, A Fatih"
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Clusters of circulating tumor cells traverse capillary-sized vessels
Published in Proceedings of the National Academy of Sciences - PNAS (03-05-2016)“…Multicellular aggregates of circulating tumor cells (CTC clusters) are potent initiators of distant organ metastasis. However, it is currently assumed that CTC…”
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Continuous Sorting of Cells Based on Differential P Selectin Glycoprotein Ligand Expression Using Molecular Adhesion
Published in Analytical chemistry (Washington) (07-11-2017)“…Cell surface molecular adhesions govern many important physiological processes and are used to identify cells for analysis and purifications. But most…”
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3
Negative enrichment of circulating tumor cells from unmanipulated whole blood with a 3D printed device
Published in Scientific reports (18-10-2021)“…Reliable and routine isolation of circulating tumor cells (CTCs) from peripheral blood would allow effective monitoring of the disease and guide the…”
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4
Capillary flow control in lateral flow assays via delaminating timers
Published in Science advances (01-10-2021)“…Lateral flow assays (LFAs) use capillary flow of liquids for simple detection of analytes. While useful for spontaneously wicking samples, the capillary flow…”
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High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells
Published in Nature communications (13-06-2022)“…Extremely rare circulating tumor cell (CTC) clusters are both increasingly appreciated as highly metastatic precursors and virtually unexplored. Technologies…”
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PANACEA: An Internet of Bio-NanoThings Application for Early Detection and Mitigation of Infectious Diseases
Published in IEEE access (01-01-2020)“…The Internet of Bio-NanoThings (IoBNT) concept envisions the connection between biological cells and the Internet. The ultimate goal of IoBNT is to catalyze a…”
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The Origins and the Current Applications of Microfluidics-Based Magnetic Cell Separation Technologies
Published in Magnetochemistry (01-01-2022)“…The magnetic separation of cells based on certain traits has a wide range of applications in microbiology, immunology, oncology, and hematology. Compared to…”
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Microbiome-Gut-Brain Axis as a Biomolecular Communication Network for the Internet of Bio-NanoThings
Published in IEEE access (01-01-2019)“…This article presents fundamental challenges in the development of a self-sustainable and biocompatible network infrastructure to interconnect the…”
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9
Paper-based multi-well depletion ELISA
Published in Lab on a chip (17-01-2023)“…Enzyme-linked immunosorbent assay (ELISA) is widely employed for detecting target molecules in bioassays including the serological assays that measure specific…”
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A microfluidic device for label-free, physical capture of circulating tumor cell clusters
Published in Nature methods (01-07-2015)“…The Cluster-Chip provides highly efficient and gentle capture of circulating tumor cell clusters from milliliters of unprocessed whole blood, making it…”
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Chemically Amplified Multiplex Detection of SARS‐CoV‐2 and Influenza A and B Viruses via Paint‐Programmed Lateral Flow Assays
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2023)“…Severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) continues to threaten lives by evolving into new variants with greater transmissibility. Although…”
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Microfluidic CODES: a scalable multiplexed electronic sensor for orthogonal detection of particles in microfluidic channels
Published in Lab on a chip (21-04-2016)“…Numerous biophysical and biochemical assays rely on spatial manipulation of particles/cells as they are processed on lab-on-a-chip devices. Analysis of…”
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13
Electronic detection of apoptotic cells on a microchip
Published in Biosensors & bioelectronics (01-01-2025)“…Robust and rapid detection of apoptosis in cells is crucially needed for diagnostics, drug discovery, studying pathogenic mechanisms and tracking patient…”
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14
Scaling code-multiplexed electrode networks for distributed Coulter detection in microfluidics
Published in Biosensors & bioelectronics (30-11-2018)“…Microfluidic devices can discriminate particles based on their properties and map them into different locations on the device. For distributed detection of…”
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Relationship between hepatocellular carcinoma circulating tumor cells and tumor volume
Published in Cancer convergence (18-07-2018)“…Background Microfluidic platforms have demonstrated the ability to isolate rare circulating tumor cells from a wide variety of cancers. Our group has recently…”
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Integrated sensor networks with error correction for multiplexed particle tracking in microfluidic chips
Published in Biosensors & bioelectronics (15-02-2021)“…Spatial manipulation of suspended cells based on their properties is an essential part of numerous microfluidic assays. To further read and analyze the…”
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An autonomous microchip for real-time, label-free immune cell analysis
Published in Biosensors & bioelectronics (15-02-2023)“…Characterization of cell populations and identification of distinct subtypes based on surface markers are needed in a variety of applications from basic…”
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18
Electronic profiling of membrane antigen expression via immunomagnetic cell manipulation
Published in Lab on a chip (21-07-2019)“…Membrane antigens control cell function by regulating biochemical interactions and hence are routinely used as diagnostic and prognostic targets in…”
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Automated lightless cytometry on a microchip with adaptive immunomagnetic manipulation
Published in Biosensors & bioelectronics (01-05-2022)“…Surface expression of cell populations are often sought as diagnostic and prognostic biomarkers in hematology-oncology and infectious diseases, making flow…”
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Enhancing size based size separation through vertical focus microfluidics using secondary flow in a ridged microchannel
Published in Scientific reports (12-12-2017)“…High throughput size based separation and sorting of bioparticles and cells is critical to a variety of biomedical processing steps for medical diagnostics and…”
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