Search Results - "Sarioğlu Yusuf"
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Synthesis, structural characterization and myorelaxant activity of 4-naphthylhexahydroquinoline derivatives containing different ester groups
Published in Journal of the Serbian Chemical Society (01-01-2016)“…The present study reports the synthesis, structural characterization and myorelaxant activity evaluation of a series of 16 novel 4-naphthyl-hexahydroquinoline…”
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2
Enhancing effect of nicotine on electrical field stimulation elicited contractile responses in isolated rabbit bladder straight muscle; the role of cannabinoid and vanilloid receptors
Published in Turkish journal of medical sciences (01-01-2022)“…Nicotine acts as an agonist of nicotinic acetylcholine receptors (nAChR). These receptors belong to a superfamily of ligand-gated ion channels. We previously…”
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3
Condensed 1,4-dihydropyridines with various esters and their calcium channel antagonist activities
Published in European journal of medicinal chemistry (01-05-2009)“…New alkyl 2,6,6-(2,7,7)-trimethyl-4-(2-fluoro-3-chloro-5-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylates and…”
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4
Nicotine Potentiates the Electrical Field Stimulation-Evoked Contraction of Non-Pregnant Rabbit Myometrium
Published in The Tohoku Journal of Experimental Medicine (2007)“…The women who smoke have lower fertility rates which might be due to harmful effects of nicotine on tubal function and menstrual cycle. Although the uterine…”
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5
OMEPRAZOLE-INDUCED RELAXATION IN RAT AORTA IS PARTLY DEPENDENT ON ENDOTHELIUM
Published in Pharmacological research (01-10-2002)“…We investigated the effect of omeprazole (1×10 −5–3×10 −4 M), an inhibitor of H +,K +-ATPase, on rat aortic rings pre-contracted with phenylephrine (10 −6 M)…”
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6
Impaired gastric motility in the gastroesophageal reflux rat model: an in vitro study
Published in The Journal of surgical research (01-12-2003)“…The present study investigated the effects of acid and mixed reflux on the responsiveness of gastric smooth muscle in the gastroesophageal reflux (GER) rat…”
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7
Microwave-assisted synthesis and myorelaxant activity of 9-indolyl-1,8-acridinedione derivatives
Published in European journal of medicinal chemistry (21-03-2014)“…In this study a microwave-assisted method was applied for the synthesis of novel 9-(substituted indolyl)-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-dione…”
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8
Effects of chronic l-DOPA administration on neurogenic and endothelium-dependent relaxation responses in rabbit corpus cavernosum
Published in Pharmacological reports (01-10-2016)“…Dopamine is a crucial central neurotransmitter that plays a fundamental role in the autonomic and somatic components of penile reflexes in animals and humans…”
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9
The effects of melatonin on electrical field stimulation-evoked biphasic twitch responses in the ipsilateral and contralateral rat vasa deferentia after unilateral testicular torsion/detorsion
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-05-2005)“…It is not known whether there is an impairment in vas deferens motility after unilateral testicular torsion/detorsion. Therefore, we aimed to determine whether…”
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10
Changes in cholinergic and nitrergic systems of defunctionalized colons after colostomy in rabbits
Published in The Journal of surgical research (01-01-2017)“…This study was designed to assess smooth muscle function and motility in defunctionalized colonic segments and subsequent changes in pathways responsible for…”
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11
Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum
Published in Iranian journal of basic medical sciences (01-04-2022)“…Endocannabinoids and nicotine regulate the neurotransmitter release in different central and peripheral synapses. Various studies in the literature demonstrate…”
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12
Investigation of myorelaxant activity of 9-aryl-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-diones in isolated rabbit gastric fundus
Published in Medicinal chemistry research (01-08-2012)“…In this study, twelve compounds having 9-aryl-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-dione structure were synthesized by reaction of…”
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13
Effects of agmatine on cognitive functions during vascular dementia in biological aging through eNOS and BDNF expression
Published in Klinik psikofarmakoloji bülteni (01-06-2017)“…Objective: Biological aging has been recognized to cause impairment of memory and the development of vascular dementia. Based on our previous work, agmatine…”
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14
Evaluation of myorelaxant activity of 7-substituted hexahydroquinoline derivatives in isolated rabbit gastric fundus
Published in European journal of medicinal chemistry (01-03-2008)“…In this article, 16 new methyl(ethyl) 4-(dichlorophenyl)-2,7-dimethyl-5-oxo-l,4,5,6,7,8-hexahydroquinoline-3-carboxylates and methyl(ethyl)…”
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15
Does Diabetes Mellitus Affect the Progress of Tolerance to Isosorbide Dinitrate (ISDN) in Corporal Tissue?
Published in Nitric oxide (01-02-2000)“…For erection to take place, the penile arteries and sinusoids have to dilate, thereby increasing the blood flow into the penis. There is increasing evidence…”
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16
Synthesis and Myorelaxant Activity of Fused 1,4-Dihydropyridines on Isolated Rabbit Gastric Fundus
Published in Drug development research (01-09-2012)“…Strategy, Management and Health Policy Preclinical Research In the present study, 25 novel condensed 1,4‐dihydropyridine (DHP) derivatives bearing…”
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17
Vasorelaxing properties of some phenylacridine type potassium channel openers in isolated rabbit thoracic arteries
Published in European journal of medicinal chemistry (01-06-2002)“…In this study, 12 new 2,2,7,7-tetramethyl-9-aryl-2,3,4,5,6,7,9,10-octahydro-1,8-acridindione derivatives were synthesised and their effects on vascular…”
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18
Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter
Published in World journal of gastroenterology : WJG (07-08-2008)“…AIM: To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitropruside…”
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19
Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro
Published in Journal of gastroenterology (01-08-2003)“…The aim of this study was to investigate the role of omeprazole and lansoprazole, H(+)-K(+) ATPase inhibitors, in gallbladder smooth muscle contractility in…”
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20
Effects of mexiletine on electrical field stimulation-induced contractile responses in the ipsilateral and contralateral vasa deferentia after unilateral testicular torsion/detorsion
Published in European surgical research (2006)“…To investigate testicular torsion-induced changes on the electrical field stimulation (EFS)-induced contractions in rabbit vasa deferentia and to evaluate the…”
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