Search Results - "Sarin, Shiv Kumar"

Potent antiviral therapy improves survival in acute on chronic liver failure due to hepatitis B virus reactivation by Philips, Cyriac Abby, Sarin, Shiv Kumar

“…Acute on chronic liver failure(ACLF)is a disease entity with a high mortality rate.The acute event arises from drugs and toxins,viral infections,bacterial…”
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Post-transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy: Sarcopenia Adds Insult to Injury by Bhatia Kapoor, Puja, Benjamin, Jaya, Tripathi, Harshita, Patidar, Yashwant, Maiwall, Rakhi, Kumar, Guresh, Joshi, Yogendra Kumar, Sarin, Shiv Kumar

“…Hepatic encephalopathy, which is a serious complication, and sarcopenia are undesirable consequences in cirrhosis. Transjugular intrahepatic portosystemic…”
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Initial psychological impact of COVID-19 and its correlates in Indian Community: An online (FEEL-COVID) survey by Varshney, Mohit, Parel, Jithin Thomas, Raizada, Neeraj, Sarin, Shiv Kumar

“…The pandemic of Corona Virus (COVID-19) hit India recently; and the associated uncertainty is increasingly testing psychological resilience of the masses. When…”
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Evaluation of the Integrative Weaning Index for Predicting the Outcome of Spontaneous Breathing Trial in Patients with Cirrhosis on Mechanical Ventilation: A Pilot Study by Sahu, Shailesh, Saluja, Vandana, Sharma, Anamika, Mitra, Lalita Gouri, Kumar, Guresh, Maiwall, Rakhi, Sarin, Shiv Kumar

“…Objective:Studies on mechanical ventilation in patients with cirrhosis have focused mainly on survival, as the disease is considered to carry a poor prognosis…”
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Key elements of the RNAi pathway are regulated by hepatitis B virus replication and HBx acts as a viral suppressor of RNA silencing by Chinnappan, Mahendran, Singh, Avishek Kumar, Kakumani, Pavan Kumar, Kumar, Gautam, Rooge, Sheetalnath Babasaheb, Kumari, Anupama, Varshney, Aditi, Rastogi, Archana, Singh, Ashok Kumar, Sarin, Shiv Kumar, Malhotra, Pawan, Mukherjee, Sunil Kumar, Bhatnagar, Raj Kamal

“…The host-mediated RNAi pathways restrict replication of viruses in plant, invertebrate and vertebrate systems. However, comparatively little is known about the…”
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Albumin in Advanced Liver Diseases: The Good and Bad of a Drug by Jagdish, Rakesh Kumar, Maras, Jaswinder Singh, Sarin, Shiv Kumar

“…Human serum albumin is the most abundant plasma protein, and it regulates diverse body functions. In patients with advanced and decompensated cirrhosis, serum…”
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Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhosis: An Open-Label, Randomized Controlled Trial of Lactulose, Probiotics, and No Therapy by AGRAWAL, Amit, BARJESH CHANDER HARMA, SHARMA, Praveen, SHIV KUMAR SARIN

“…Lactulose is effective in secondary prophylaxis of hepatic encephalopathy (HE). Probiotics improves minimal hepatic encephalopathy (MHE), which predisposes to…”
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Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute‐on‐chronic liver failure by Garg, Hitendra, Sarin, Shiv Kumar, Kumar, Manoj, Garg, Vishal, Sharma, Barjesh Chander, Kumar, Ashish

“…Spontaneous reactivation of chronic hepatitis B (CHB) is an important cause of acute‐on‐chronic liver failure (ACLF). Antiviral drugs may help reduce the high…”
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Antitubercular therapy in patients with cirrhosis:Challenges and options by Kumar, Naveen, Kedarisetty, Chandan Kumar, Kumar, Sachin, Khillan, Vikas, Sarin, Shiv Kumar

“…Tuberculosis(TB)has been a human disease for centuries.Its frequency is increased manyfold in patients with liver cirrhosis.The gold standard of TB management…”
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Identification and characterization of genotype A and D recombinant hepatitis B virus from Indian chronic HBV isolates by Chauhan, Ranjit, Kazim, Syed-Naqui, Kumar, Manoj, Bhattacharjee, Jayashree, Krishnamoorthy, Narayanasamy, Sarin, Shiv-Kumar

“…AIM： To confirm the presence of recombination, fulllength hepatitis B virus （HBV） from chronic patients was sequenced and analyzed. METHODS： Full-length HBV…”
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Secondary Prophylaxis of Hepatic Encephalopathy: An Open-Label Randomized Controlled Trial of Lactulose Versus Placebo by Sharma, Barjesh Chander, Sharma, Praveen, Agrawal, Amit, Sarin, Shiv Kumar

“…Background & Aims Hepatic encephalopathy (HE) is associated with a poor prognosis. Lactulose is used for the treatment of HE. There is no study on the…”
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Idiopathic portal hypertension and extrahepatic portal venous obstruction by Khanna, Rajeev, Sarin, Shiv Kumar

“…Background Idiopathic portal hypertension (IPH) and extrahepatic portal venous obstruction (EHPVO) are non-cirrhotic vascular causes of portal hypertension…”
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Maternal and Fetal Outcomes in Pregnant Women with Acute Hepatitis E Virus Infection by PATRA, Sharda, KUMAR, Ashish, SHUBHA SAGAR TRIVEDI, PURI, Manju, SHIV KUMAR SARIN

“…Hepatitis E virus (HEV) infection is known to cause severe liver disease in pregnant women. It is unclear whether obstetric and fetal outcomes are worse in…”
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A randomized controlled trial comparing lactulose, probiotics, and L-ornithine L-aspartate in treatment of minimal hepatic encephalopathy by Mittal, Vibhu Vibhas, Sharma, Barjesh Chander, Sharma, Praveen, Sarin, Shiv Kumar

“…BACKGROUNDMinimal hepatic encephalopathy (MHE) impairs daily functioning and health-related quality of life (HRQoL). The modalities of treatment of MHE have…”
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Predictors of steroid non-response and new approaches in severe alcoholic hepatitis by Sarin, Shiv Kumar, Sharma, Shvetank

“…Severe alcoholic hepatitis (SAH) remains a disease with high mortality. Steroid is the main stay and has been shown to give modest 28-day survival benefit in…”
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Pooled RNA sample reverse transcriptase real time PCR assay for SARS CoV-2 infection: A reliable, faster and economical method by Gupta, Ekta, Padhi, Abhishek, Khodare, Arvind, Agarwal, Reshu, Ramachandran, Krithiga, Mehta, Vibha, Kilikdar, Mousumi, Dubey, Shantanu, Kumar, Guresh, Sarin, Shiv Kumar

“…Corona virus disease 2019 (COVID-19) which initially started as a cluster of pneumonia cases in the Wuhan city of China has now become a full-blown pandemic…”
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Anatomic Recanalization of Hepatic Vein and Inferior Vena Cava versus Direct Intrahepatic Portosystemic Shunt Creation in Budd-Chiari Syndrome: Overall Outcome and Midterm Transplant-Free Survival by Mukund, Amar, Mittal, Kartik, Mondal, Aniket, Sarin, Shiv Kumar

“…To assess overall outcome and midterm transplant-free survival of patients with Budd-Chiari syndrome (BCS) undergoing radiologic interventions including…”
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Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis by Das, Sukanta, Maras, Jaswinder Singh, Hussain, Md. Shabir, Sharma, Shvetank, David, Paul, Sukriti, Sukriti, Shasthry, Saggere Muralikrishna, Maiwall, Rakhi, Trehanpati, Nirupama, Singh, Tej P., Sarin, Shiv Kumar

“…Albumin is a potent scavenger of reactive oxygen species (ROS). However, modifications in albumin structure may reduce its antioxidant properties and modulate…”
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Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure by Garg, Hitendra, Kumar, Ashish, Garg, Vishal, Sharma, Praveen, Sharma, Barjesh Chander, Sarin, Shiv Kumar

“…Abstract Background Acute-on-chronic liver failure (ACLF) is characterised by acute hepatic insult manifesting as jaundice and coagulopathy, complicated within…”
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Randomized controlled trial comparing lactulose plus albumin versus lactulose alone for treatment of hepatic encephalopathy by Sharma, Barjesh Chander, Singh, Jatinderpal, Srivastava, Siddharth, Sangam, Alok, Mantri, Alok Kumar, Trehanpati, Nirupma, Sarin, Shiv Kumar

“…Background Hepatic encephalopathy (HE) is associated with poor prognosis and treatment of HE is primarily directed at the reduction of the blood ammonia…”
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