Search Results - "Sarig, R"
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p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity
Published in Cell death and differentiation (01-05-2013)“…Proper regulation of white and brown adipogenic differentiation is important for maintaining an organism’s metabolic profile in a homeostatic state. The recent…”
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p53 is balancing development, differentiation and de-differentiation to assure cancer prevention
Published in Carcinogenesis (New York) (01-09-2010)“…Many of the roles played by the tumor suppressor p53 in restraining cancer initiation and progression are well established. These include the ability of p53 to…”
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Examination of the Interproximal Wear Mechanism: Facet Morphology and Surface Texture Analysis
Published in Journal of dental research (01-12-2018)“…Dentition is considered a dynamic system with forces that directly affect dental treatment stability and success. Understanding the biomechanical forces that…”
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p53 Counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition
Published in Cell death and differentiation (01-02-2013)“…The process of somatic cell reprogramming is gaining increasing interest as reprogrammed cells are considered to hold a great therapeutic potential. However,…”
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Can an iPS cell secure its genomic fidelity?
Published in Cell death and differentiation (01-05-2011)Get full text
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The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele
Published in Cell death and differentiation (01-09-2014)“…p53 loss of heterozygosity (p53LOH) is frequently observed in Li-Fraumeni syndrome (LFS) patients who carry a mutant (Mut) p53 germ-line mutation. Here, we…”
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The association between dental wear and reduced vertical dimension of the face: A morphologic study on human skulls
Published in Archives of oral biology (01-01-2015)“…Highlights • A positive correlation was observed between age and significant dental wear. • No statistically significant differences were noted between the men…”
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Targeted Inactivation of Dp71, the Major Non-Muscle Product of the DMD Gene: Differential Activity of the Dp71 Promoter during Development
Published in Human molecular genetics (01-01-1999)“…The dystrophin gene, which is defective in Duchenne muscular dystrophy (DMD), also encodes a number of smaller products controlled by internal promoters. Dp71,…”
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Isotopological remeshing and statistical shape analysis: Enhancing premolar tooth wear classification and simulation with machine learning
Published in Journal of dentistry (01-10-2024)“…The aim of this study was to evaluate the accuracy of a combined approach based on an isotopological remeshing and statistical shape analysis (SSA) to capture…”
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Proapoptotic BID Is an ATM Effector in the DNA-Damage Response
Published in Cell (26-08-2005)“…The “BH3-only” proapoptotic BCL-2 family members are sentinels of intracellular damage. Here, we demonstrated that the BH3-only BID protein partially localizes…”
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Increased efficiency of homologous recombination in ES cells by cleavage at both ends of homology in the targeting vector
Published in Transgenic research (01-04-2000)“…Gene inactivation by homologous recombination has become an important approach to study the function of genes and proteins in mice. A major limitation of this…”
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Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina
Published in Human molecular genetics (01-07-2003)“…The abnormal retinal neurotransmission observed in Duchenne muscular dystrophy (DMD) patients and in some genotypes of mice lacking dystrophin has been…”
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tBID Homooligomerizes in the Mitochondrial Membrane to Induce Apoptosis
Published in The Journal of biological chemistry (05-04-2002)“…Activation of the tumor necrosis factor R1/Fas receptor results in the cleavage of cytosolic BID to truncated tBID. tBID translocates to the mitochondria to…”
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Treatment by glatiramer acetate improves cell therapy in experimental autoimmune encephalomyelitis
Published in Multiple sclerosis (01-09-2008)“…Background: Stem cell transplantation is a promising therapeutic strategy. In multiple sclerosis (MS) in particular, stem cells differentiating into…”
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Transplanted myogenic progenitor cells express neuronal markers in the CNS and ameliorate disease in Experimental Autoimmune Encephalomyelitis
Published in Journal of neuroimmunology (30-10-2009)“…Abstract This study explores the potential of non-neural progenitor cells for CNS cell therapy. Muscle progenitor cells (MPCs), transplanted either…”
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BID-D59A Is a Potent Inducer of Apoptosis in Primary Embryonic Fibroblasts
Published in The Journal of biological chemistry (21-03-2003)“…The proapoptotic activity of BID seems to solely depend upon its cleavage to truncated tBID. Here we demonstrate that expression of a caspase-8 non-cleavable…”
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Nanog inhibits the switch of myogenic cells towards the osteogenic lineage
Published in Biochemical and biophysical research communications (25-01-2008)“…The homeodomain transcription factor Nanog has been implicated in inhibiting differentiation and controlling pluripotency of embryonic stem (ES) cells. We used…”
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Socioeconomic and physical characteristics of degenerative lumbar spinal stenosis individuals
Published in Spine (Philadelphia, Pa. 1976) (01-02-2013)“…Study Design. A descriptive study of the association between demographic factors, and physical characteristics, and degenerative lumbar spinal stenosis…”
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Ignoring Rock Won't Make It Go Away
Published in The Education digest (1970)“…Since American youth have a strong preference for rock music, music educators should cater to this bias. Youth music is here to stay, and the educator's role…”
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