Search Results - "Sargun, Artur"

Siderophore Immunization Restricted Colonization of Adherent-Invasive Escherichia coli and Ameliorated Experimental Colitis by Gerner, Romana R, Hossain, Suzana, Sargun, Artur, Siada, Kareem, Norton, Grant J, Zheng, Tengfei, Neumann, Wilma, Nuccio, Sean-Paul, Nolan, Elizabeth M, Raffatellu, Manuela

“…Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the gastrointestinal tract and profound alterations to the gut microbiome…”
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The Disobeying 'Soldier': Use of an Achiral Group to Modulate Chiral Induction in PNA Duplexes by Sargun, Artur, Fang, Yanhaomin, Achim, Catalina

“…Peptide nucleic acid (PNA) is a synthetic analogue of DNA in which the natural nucleobases A, G, C, and T are linked to an achiral, charge neutral,…”
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Harnessing Iron Acquisition Machinery to Target Enterobacteriaceae by Sargun, Artur, Gerner, Romana R, Raffatellu, Manuela, Nolan, Elizabeth M

“…Abstract Infections caused by Gram-negative bacteria can be challenging to treat due to the outer membrane permeability barrier and the increasing emergence of…”
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Development of Cu2+-Based Distance Methods and Force Field Parameters for the Determination of PNA Conformations and Dynamics by EPR and MD Simulations by Gamble Jarvi, Austin, Sargun, Artur, Bogetti, Xiaowei, Wang, Junmei, Achim, Catalina, Saxena, Sunil

“…Peptide nucleic acids (PNAs) are a promising group of synthetic analogues of DNA and RNA that offer several distinct advantages over the naturally occurring…”
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Conjugation to Native and Nonnative Triscatecholate Siderophores Enhances Delivery and Antibacterial Activity of a β‑Lactam to Gram-Negative Bacterial Pathogens by Motz, Rachel N., Guo, Chuchu, Sargun, Artur, Walker, Gregory T., Sassone-Corsi, Martina, Raffatellu, Manuela, Nolan, Elizabeth M.

“…Developing new antibiotics and delivery strategies is of critical importance for treating infections caused by Gram-negative bacterial pathogens. Hijacking…”
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Enterobactin- and salmochelin-β-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic Escherichia coli CFT073 by Sargun, Artur, Johnstone, Timothy C, Zhi, Hui, Raffatellu, Manuela, Nolan, Elizabeth M

“…The design and synthesis of narrow-spectrum antibiotics that target a specific bacterial strain, species, or group of species is a promising strategy for…”
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TARGETING SIDEROPHORES TO REDUCE COLONIZATION OF ADHERENT INVASIVE E. COLI IN CROHN’S DISEASE by Gerner, Romana, Hossain, Suzana, Siada, Kareem, Sargun, Artur, Neumann, Wilma, Nolan, Elizabeth, Raffatellu, Manuela

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Development of Cu 2+ -Based Distance Methods and Force Field Parameters for the Determination of PNA Conformations and Dynamics by EPR and MD Simulations by Gamble Jarvi, Austin, Sargun, Artur, Bogetti, Xiaowei, Wang, Junmei, Achim, Catalina, Saxena, Sunil

“…Peptide nucleic acids (PNAs) are a promising group of synthetic analogues of DNA and RNA that offer several distinct advantages over the naturally occurring…”
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TARGETING SIDEROPHORES TO REDUCE COLONIZATION OF ADHERENT INVASIVE E. COLI IN CROHN’S DISEASE by Gerner, Romana, Hossain, Suzana, Siada, Kareem, Sargun, Artur, Neumann, Wilma, Nolan, Elizabeth, Raffatellu, Manuela

“…The pathovar adherent-invasive Escherichia coli (AIEC) is a mucosa-associated bacterium that is frequently found in patients with Crohn’s disease (CD), but…”
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A Rationally Designed Complex Replenishes the Transferrin Iron Pool Directly and with High Specificity by Sargun, Artur, Fisher, Allison L., Wolock, Anna S., Phillips, Sydney, Sojoodi, Mozhdeh, Khanna, Soumya, Babitt, Jodie L., Gale, Eric M.

“…Many forms of anemia are caused or complicated by pathologic restriction of iron (Fe). Chronic inflammation and certain genetic mutations decrease the activity…”
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Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of β‑Lactam Antibiotics against Nontyphoidal Salmonella by Sargun, Artur, Sassone-Corsi, Martina, Zheng, Tengfei, Raffatellu, Manuela, Nolan, Elizabeth M

“…The pathogen Salmonella enterica is a leading cause of infection worldwide. Nontyphoidal Salmonella (NTS) serovars typically cause inflammatory diarrhea in…”
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Molecular Conductance of Nicked Nucleic Acid Duplexes by Beall, Edward, Sargun, Artur, Ulku, Selma, Bae, Yookyung, Wierzbinski, Emil, Clever, Caleb, Waldeck, David H, Achim, Catalina

“…This work investigates how the conductance of a nucleic acid duplex with a “nick” in its backbone compares with that of a duplex with a fully covalent…”
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Conjugation to enterobactin and salmochelin S4 enhances the antimicrobial activity and selectivity of β-lactam antibiotics against non-typhoidal Salmonella by Sargun, Artur, Sassone-Corsi, Martina, Zheng, Tengfei, Raffatellu, Manuela, Nolan, Elizabeth M.

“…The pathogen Salmonella enterica is a leading cause of infection worldwide. Non-typhoidal Salmonella (NTS) serovars typically cause inflammatory diarrhea in…”
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Enterobactin- and salmochelin-β-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic CFT073 by Sargun, Artur, Johnstone, Timothy C, Zhi, Hui, Raffatellu, Manuela, Nolan, Elizabeth M

“…The design and synthesis of narrow-spectrum antibiotics that target a specific bacterial strain, species, or group of species is a promising strategy for…”
Get full text