Search Results - "Sargas, Claudia"

Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene by Liquori, Alessandro, Ibañez, Mariam, Sargas, Claudia, Sanz, Miguel Ángel, Barragán, Eva, Cervera, José

“…Although acute promyelocytic leukemia (APL) is one of the most characterized forms of acute myeloid leukemia (AML), the molecular mechanisms involved in the…”
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Validation of mutated CEBPA bZIP as a distinct prognosis entity in acute myeloid leukemia: a study by the Spanish PETHEMA registry by De la Torre, Esther Prados, Serrano, Josefina, Martínez-Cuadrón, David, Torres, Laura, Sargas, Claudia, Ayala, Rosa, Bilbao-Sieyro, Cristina, Chillón, María Carmen, Larráyoz, María José, Soria, Elena, Aparicio-Pérez, Clara, Bergua, Juan M, Bernal, Teresa, Gil, Cristina, Tormo, Mar, Algarra, Lorenzo, Alonso-Domínguez, Juan M, Rodriguez-Arbolí, Eduardo, Martínez-Sanchez, Pilar, Oliva, Ana, Colorado-Araujo, Ana M, Rodríguez-Medina, Carlos, Vives, Susana, Hermosín, Lourdes, Martínez-López, Joaquín, García-Sanz, Ramón, Pérez-Simón, José A, Calasanz, María José, Gómez-Casares, María Teresa, Barragán, Eva, Sánchez-García J, Joaquín, Montesinos, Pau

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Prognostic significance of FLT3-ITD length in AML patients treated with intensive regimens by Castaño-Bonilla, Tamara, Alonso-Dominguez, Juan M., Barragán, Eva, Rodríguez-Veiga, Rebeca, Sargas, Claudia, Gil, Cristina, Chillón, Carmen, Vidriales, María B., García, Raimundo, Martínez-López, Joaquín, Ayala, Rosa, Larrayoz, María J., Anguita, Eduardo, Cuello, Rebeca, Cantalapiedra, Alberto, Carrillo, Estrella, Soria-Saldise, Elena, Labrador, Jorge, Recio, Isabel, Algarra, Lorenzo, Rodríguez-Medina, Carlos, Bilbao-Syeiro, Cristina, López-López, Juan A., Serrano, Josefina, De Cabo, Erik, Sayas, María J., Olave, María T., Sánchez-García, Joaquín, Mateos, Mamen, Blas, Carlos, López-Lorenzo, Jose L., Lainez-Gonzalez, Daniel, Serrano, Juana, Martínez-Cuadrón, David, Sanz, Miguel A., Montesinos, Pau

“…FLT3- ITD mutations are detected in approximately 25% of newly diagnosed adult acute myeloid leukemia (AML) patients and confer an adverse prognosis. The FLT3…”
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Design and Validation of a Custom Next-Generation Sequencing Panel in Pediatric Acute Lymphoblastic Leukemia by Gil, José Vicente, Such, Esperanza, Sargas, Claudia, Simarro, Javier, Miralles, Alberto, Pérez, Gema, de Juan, Inmaculada, Palanca, Sarai, Avetisyan, Gayane, Santiago, Marta, Fuentes, Carolina, Fernández, José María, Vicente, Ana Isabel, Romero, Samuel, Llop, Marta, Barragán, Eva

“…The molecular landscape of acute lymphoblastic leukemia (ALL) is highly heterogeneous, and genetic lesions are clinically relevant for diagnosis, risk…”
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Analysis of SNP Array Abnormalities in Patients with DE NOVO Acute Myeloid Leukemia with Normal Karyotype by Ibáñez, Mariam, Such, Esperanza, Onecha, Esther, Gómez-Seguí, Inés, Liquori, Alessandro, Sellés, Jorge, Hervás-Marín, David, Barragán, Eva, Ayala, Rosa, LLop, Marta, López-Pavía, María, Rapado, Inmaculada, Neef, Alex, Sanjuan-Pla, Alejandra, Sargas, Claudia, Gonzalez-Romero, Elisa, Boluda-Navarro, Mireia, Andreu, Rafa, Senent, Leonor, Montesinos, Pau, Martínez-López, Joaquín, Angel Sanz, Miguel, Sanz, Guillermo, Cervera, José

“…Nearly 50% of patients with de novo acute myeloid leukemia (AML) harbor an apparently normal karyotype (NK) by conventional cytogenetic techniques showing a…”
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The Q-LAMP Method Represents a Valid and Rapid Alternative for the Detection of the BCR-ABL1 Rearrangement in Philadelphia-Positive Leukemias by Stella, Stefania, Gottardi, Enrico Marco, Favout, Valeria, Barragan Gonzalez, Eva, Errichiello, Santa, Vitale, Silvia Rita, Fava, Carmen, Luciano, Luigia, Stagno, Fabio, Grimaldi, Francesco, Pironi, Lucrezia, Sargas Simarro, Claudia, Vigneri, Paolo, Izzo, Barbara

“…Molecular detection of the fusion transcripts is necessary for the genetic confirmation of a chronic myeloid leukemia diagnosis and for the risk classification…”
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The role of next-generation sequencing in acute myeloid leukemia by Llop, Marta, Sargas, Claudia, Barragán, Eva

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The role of next-generation sequencing in acute myeloid leukemia by Llop, Marta, Sargas, Claudia, Barragán, Eva

“…Purpose of review The development of high-throughput techniques like next-generation sequencing (NGS) has unraveled the genetic profile of cancer. In this…”
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Correction: Liquori et al. Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene. Cancers 2020, 12, 624 by Liquori, Alessandro, Ibañez, Mariam, Sargas, Claudia, Sanz, Miguel Ángel, Barragán, Eva, Cervera, José

“…The authors wish to make the following corrections to this paper [...]…”
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Treatment Outcomes in Unfit Patients with Newly Acute Myeloid Leukemia According to IDH1 Mutational Status: Real World Evidence from the Pethema Epidemiologic Registry by Martinez-Cuadron, David, Boluda, Blanca, Algarra, Jesús Lorenzo, Bergua Burgues, Juan Miguel, Rodriguez Veiga, Rebeca, Martinez Sanchez, Pilar, Serrano, Josefina, Ramos-Ortega, Fernando Jesús, Pérez-Simón, Jose A., Tormo, Mar, Lopez Lorenzo, Jose Luis, Lavilla, Esperanza, Bernal Del Castillo, Teresa, Rodríguez-Medina, Carlos, Garay, Maria Carmen GARCIA, Sayas Lloris, Maria Jose, Gil, Cristina, Olave Rubio, Maria Teresa, Garcia Boyero, Raimundo, Vives, Susana, Foncillas, Maria Angeles, Labrador, Jorge, Ibañez, Francisco, Cabello, Ana, Herrera Puente, Pilar, González González, Bernardo Javier, Barragán, Eva, Sargas, Claudia, Ayala, Rosa, Chillon, Carmen, Montesinos, Pau

“…Background: Current treatment of unfit acute myeloid leukemia (AML) patients include hypomethylating agents (HMA) with or without venetoclax, low-dose…”
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Networking for advanced molecular diagnosis in acute myeloid leukemia patients is possible: the PETHEMA NGS-AML project by Sargas, Claudia, Ayala, Rosa, Chillón, María Carmen, Larráyoz, María J, Carrillo-Cruz, Estrella, Bilbao, Cristina, Yébenes-Ramírez, Manuel, Llop, Marta, Rapado, Inmaculada, García-Sanz, Ramón, Vázquez, Iria, Soria, Elena, Florido-Ortega, Yanira, Janusz, Kamila, Botella, Carmen, Serrano, Josefina, Martínez-Cuadrón, David, Bergua, Juan, Amigo, Mari Luz, Martínez-Sánchez, Pilar, Tormo, Mar, Bernal, Teresa, Herrera-Puente, Pilar, García, Raimundo, Algarra, Lorenzo, Sayas, María J, Costilla-Barriga, Lisette, Pérez-Santolalla, Esther, Marchante, Inmaculada, Lavilla-Rubira, Esperanza, Noriega, Víctor, Alonso-Domínguez, Juan M, Sanz, Miguel Á, Sánchez-Garcia, Joaquín, Gómez-Casares, María T, Pérez-Simón, José A, Calasanz, María J, González-Díaz, Marcos, Martínez-López, Joaquín, Barragán, Eva, Montesinos, Pau

“…Next-Generation Sequencing has recently been introduced to efficiently and simultaneously detect genetic variations in acute myeloid leukemia. However, its…”
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Conventional PCR Versus Next Generation Sequencing for Diagnosis of FLT3, IDH and NPM1 Mutations in Acute Myeloid Leukemia: Interim Analysis of the PCR-LMA Protocol of the Pethema Group by Boluda, Blanca, Sargas, Claudia, Ayala, Rosa, Larrayoz, Maria Jose, Chillón Santos, María Carmen, Carrillo-Cruz, Estrella, Bilbao, Cristina, Prados de La Torre, Esther, Navarro-Vicente, Irene, Martinez-Cuadron, David, Rodríguez-Veiga, Rebeca, Gil, Cristina, Bernal del Castillo, Teresa, Bergua Burgués, Juan Miguel, Algarra, Lorenzo, Tormo, Mar, Martinez Sanchez, Pilar, Soria, Elena, Serrano, Josefina, Alonso Dominguez, Juan Manuel, García-Boyero, Raimundo, Amigo, Maria Luz, Herrera, Pilar, Sayas, Maria Jose, Lavilla, Esperanza, Martínez-López, Joaquín, Calasanz, María José, García-Sanz, Ramón, Perez-Simon, Jose A., Gómez-Casares, María Teresa, Sánchez-Garcia, Joaquín, Barragán, Eva, Montesinos, Pau

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Pethema NGS-AML Project. Final Analysis and Clinical Validation of New Genomic Classifications by Sargas, Claudia, Ayala, Rosa, Larrayoz, Maria Jose, Chillon, Carmen, Carrillo, Estrella, Bilbao, Cristina, Prados de La Torre, Esther, Martinez-Cuadron, David, Rodríguez-Veiga, Rebeca, Gil, Cristina, Bernal, Teresa, Bergua Burgués, Juan Miguel, Algarra, Lorenzo, Tormo, Mar, Martínez Sánchez, Pilar, Soria, Elena, Serrano, Josefina, Alonso Dominguez, Juan Manuel, García-Boyero, Raimundo, Amigo, Maria Luz, Herrera, Pilar, Sayas, María J., Lavilla, Esperanza, Martínez-López, Joaquín, Calasanz, María José, García-Sanz, Ramón, Perez-Simon, Jose A., Gómez-Casares, María Teresa, Sánchez-Garcia, Joaquín, Barragán, Eva, Montesinos, Pau

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Author Correction: Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA by Sánchez, Ricardo, Dorado, Sara, Ruíz-Heredia, Yanira, Martín-Muñoz, Alejandro, Rosa-Rosa, Juan Manuel, Ribera, Jordi, García, Olga, Jimenez-Ubieto, Ana, Carreño-Tarragona, Gonzalo, Linares, María, Rufián, Laura, Juárez, Alexandra, Carrillo, Jaime, Espino, María José, Cáceres, Mercedes, Expósito, Sara, Cuevas, Beatriz, Vanegas, Raúl, Casado, Luis Felipe, Torrent, Anna, Zamora, Lurdes, Mercadal, Santiago, Coll, Rosa, Cervera, Marta, Morgades, Mireia, Hernández-Rivas, José Ángel, Bravo, Pilar, Serí, Cristina, Anguita, Eduardo, Barragán, Eva, Sargas, Claudia, Ferrer-Marín, Francisca, Sánchez-Calero, Jorge, Sevilla, Julián, Ruíz, Elena, Villalón, Lucía, del Mar Herráez, María, Riaza, Rosalía, Magro, Elena, Steegman, Juan Luis, Wang, Chongwu, de Toledo, Paula, García-Gutiérrez, Valentín, Ayala, Rosa, Ribera, Josep-Maria, Barrio, Santiago, Martínez-López, Joaquín

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Improving the prediction of acute myeloid leukaemia outcomes by complementing mutational profiling with ex vivo chemosensitivity by Onecha, Esther, Ruiz‐Heredia, Yanira, Martínez‐Cuadrón, David, Barragán, Eva, Martinez‐Sanchez, Pilar, Linares, María, Rapado, Inmaculada, Perez‐Oteyza, Jaime, Magro, Elena, Herrera, Pilar, Rojas, José Luis, Gorrochategui, Julián, Villoria, Jesús, Boluda, Blanca, Sargas, Claudia, Ballesteros, Joan, Montesinos, Pau, Martínez‐López, Joaquín, Ayala, Rosa

“…Summary Refractoriness to induction therapy and relapse after complete remission are the leading causes of death in patients with acute myeloid leukaemia…”
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Nationwide Laboratory Network for AML Cross-Validated NGS Studies: Results from a Real-Life Cohort of the Pethema Group by Sargas, Claudia, Ayala, Rosa, Chillon, Carmen, Larrayoz, Maria Jose, Carrillo, Estrella, Bilbao, Cristina, Yébenes, Manuel, Llop, Marta, Rapado, Inmaculada, Garcia-Sanz, Ramon, Vazquez, Iria, Soria, Elena, Sánchez-Sosa, Santiago, Janusz, Kamila, Botella, Carmen, Serrano, Josefina, Martinez-Cuadron, David, Bergua, Juan-Miguel, Amigo, Maria Luz, Martinez Sanchez, Pilar, Tormo, Mar, Bernal, Teresa, Herrera-Puente, Pilar, García-Boyero, Raimundo, Algarra, Lorenzo, Sayas, Maria Jose, Costilla-Barriga, Lisette, Pérez-Santolalla, Esther, Marchante, Inmaculada, Lavilla-Rubira, Esperanza, Noriega, Víctor, Alonso Dominguez, Juan Manuel, Sanz, Miguel A., Sánchez, Joaquín, Gómez-Casares, María Teresa, Perez-Simon, Jose A., Calasanz, María José, González, Marcos, Martínez-López, Joaquín, Barragán, Eva, Montesinos, Pau

“…Next-Generation Sequencing (NGS) has recently been introduced to efficiently and simultaneously detect genetic variations in acute myeloid leukemia (AML)…”
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Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA by Sánchez, Ricardo, Dorado, Sara, Ruíz-Heredia, Yanira, Martín-Muñoz, Alejandro, Rosa-Rosa, Juan Manuel, Ribera, Jordi, García, Olga, Jimenez-Ubieto, Ana, Carreño-Tarragona, Gonzalo, Linares, María, Rufián, Laura, Juárez, Alexandra, Carrillo, Jaime, Espino, María José, Cáceres, Mercedes, Expósito, Sara, Cuevas, Beatriz, Vanegas, Raúl, Casado, Luis Felipe, Torrent, Anna, Zamora, Lurdes, Mercadal, Santiago, Coll, Rosa, Cervera, Marta, Morgades, Mireia, Hernández-Rivas, José Ángel, Bravo, Pilar, Serí, Cristina, Anguita, Eduardo, Barragán, Eva, Sargas, Claudia, Ferrer-Marín, Francisca, Sánchez-Calero, Jorge, Sevilla, Julián, Ruíz, Elena, Villalón, Lucía, del Mar Herráez, María, Riaza, Rosalía, Magro, Elena, Steegman, Juan Luis, Wang, Chongwu, de Toledo, Paula, García-Gutiérrez, Valentín, Ayala, Rosa, Ribera, Josep-Maria, Barrio, Santiago, Martínez-López, Joaquín

“…The screening of the BCR::ABL1 kinase domain (KD) mutation has become a routine analysis in case of warning/failure for chronic myeloid leukemia (CML) and…”
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Clinical Utility of a Next-Generation Sequencing Panel for Acute Myeloid Leukemia Diagnostics by Alonso, Carmen M., Llop, Marta, Sargas, Claudia, Pedrola, Laia, Panadero, Joaquín, Hervás, David, Cervera, José, Such, Esperanza, Ibáñez, Mariam, Ayala, Rosa, Martínez-López, Joaquín, Onecha, Esther, de Juan, Inmaculada, Palanca, Sarai, Martínez-Cuadrón, David, Rodríguez-Veiga, Rebeca, Boluda, Blanca, Montesinos, Pau, Sanz, Guillermo, Sanz, Miguel A., Barragán, Eva

“…Next-generation sequencing (NGS) has redefined the genetic landscape of acute myeloid leukemia (AML), providing new molecular markers for diagnostic and…”
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A phase I trial of selinexor plus FLAG-Ida for the treatment of refractory/relapsed adult acute myeloid leukemia patients by Martínez Sánchez, María P., Megías-Vericat, Juan Eduardo, Rodríguez-Veiga, Rebeca, Vives, Susana, Bergua, Juan Miguel, Torrent, Anna, Suárez-Varela, Sara, Boluda, Blanca, Martínez-López, Joaquín, Cano-Ferri, Isabel, Acuña-Cruz, Evelyn, Torres-Miñana, Laura, Martín-Herreros, Beatriz, Serrano, Alfons, Sempere, Amparo, Barragán, Eva, Sargas, Claudia, Sanz, Miguel, Martínez-Cuadrón, David, Montesinos, Pau

“…Prognosis for relapsed or refractory (R/R) acute myeloid leukemia (AML) despite salvage therapy is dismal. This phase I dose-escalation trial assessed the…”
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Molecular Landscape and Validation of New Genomic Classification in 2668 Adult AML Patients: Real Life Data from the PETHEMA Registry by Sargas, Claudia, Ayala, Rosa, Larráyoz, María José, Chillón, María Carmen, Carrillo-Cruz, Estrella, Bilbao-Sieyro, Cristina, Prados de la Torre, Esther, Martínez-Cuadrón, David, Rodríguez-Veiga, Rebeca, Boluda, Blanca, Gil, Cristina, Bernal, Teresa, Bergua, Juan Miguel, Algarra, Lorenzo, Tormo, Mar, Martínez-Sánchez, Pilar, Soria, Elena, Serrano, Josefina, Alonso-Domínguez, Juan Manuel, García-Boyero, Raimundo, Amigo, María Luz, Herrera-Puente, Pilar, Sayas, María José, Lavilla-Rubira, Esperanza, Martínez-López, Joaquín, Calasanz, María José, García-Sanz, Ramón, Pérez-Simón, José Antonio, Gómez-Casares, María Teresa, Sánchez-García, Joaquín, Barragán, Eva, Montesinos, Pau, On Behalf Of Pethema Group

“…Next-Generation Sequencing (NGS) implementation to perform accurate diagnosis in acute myeloid leukemia (AML) represents a major challenge for molecular…”
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