Search Results - "Saredo Said"

Pleiotropic genetic architecture and novel loci for C-reactive protein levels by Koskeridis, Fotios, Evangelou, Evangelos, Said, Saredo, Boyle, Joseph J., Elliott, Paul, Dehghan, Abbas, Tzoulaki, Ioanna

“…C-reactive protein is involved in a plethora of pathophysiological conditions. Many genetic loci associated with C-reactive protein are annotated to lipid and…”
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Genetic analysis of over half a million people characterises C-reactive protein loci by Said, Saredo, Pazoki, Raha, Karhunen, Ville, Võsa, Urmo, Ligthart, Symen, Bodinier, Barbara, Koskeridis, Fotios, Welsh, Paul, Alizadeh, Behrooz Z., Chasman, Daniel I., Sattar, Naveed, Chadeau-Hyam, Marc, Evangelou, Evangelos, Jarvelin, Marjo-Riitta, Elliott, Paul, Tzoulaki, Ioanna, Dehghan, Abbas

“…Chronic low-grade inflammation is linked to a multitude of chronic diseases. We report the largest genome-wide association study (GWAS) on C-reactive protein…”
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Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes by Pazoki, Raha, Vujkovic, Marijana, Elliott, Joshua, Evangelou, Evangelos, Gill, Dipender, Ghanbari, Mohsen, van der Most, Peter J., Pinto, Rui Climaco, Wielscher, Matthias, Farlik, Matthias, Zuber, Verena, de Knegt, Robert J., Snieder, Harold, Uitterlinden, André G., Lynch, Julie A., Jiang, Xiyun, Said, Saredo, Kaplan, David E., Lee, Kyung Min, Serper, Marina, Carr, Rotonya M., Tsao, Philip S., Atkinson, Stephen R., Dehghan, Abbas, Tzoulaki, Ioanna, Ikram, M. Arfan, Herzig, Karl-Heinz, Järvelin, Marjo-Riitta, Alizadeh, Behrooz Z., O’Donnell, Christopher J., Saleheen, Danish, Voight, Benjamin F., Chang, Kyong-Mi, Thursz, Mark R., Elliott, Paul

“…Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular diseases. We perform genetic analysis on serum levels of…”
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Author Correction: Genetic analysis of over half a million people characterises C-reactive protein loci by Said, Saredo, Pazoki, Raha, Karhunen, Ville, Võsa, Urmo, Ligthart, Symen, Bodinier, Barbara, Koskeridis, Fotios, Welsh, Paul, Alizadeh, Behrooz Z., Chasman, Daniel I., Sattar, Naveed, Chadeau-Hyam, Marc, Evangelou, Evangelos, Jarvelin, Marjo-Riitta, Elliott, Paul, Tzoulaki, Ioanna, Dehghan, Abbas

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Proteo-genomic analyses in relatively lean Chinese adults identify proteins and pathways that affect general and central adiposity levels by Iona, Andri, Yao, Pang, Pozarickij, Alfred, Kartsonaki, Christiana, Said, Saredo, Wright, Neil, Lin, Kuang, Millwood, Iona, Fry, Hannah, Mazidi, Mohsen, Wang, Baihan, Chen, Yiping, Du, Huaidong, Yang, Ling, Avery, Daniel, Schmidt, Dan, Sun, Dianjianyi, Pei, Pei, Lv, Jun, Yu, Canqing, Hill, Michael, Chen, Junshi, Bragg, Fiona, Bennett, Derrick, Walters, Robin, Li, Liming, Clarke, Robert, Chen, Zhengming

“…Adiposity is an established risk factor for multiple diseases, but the causal relationships of different adiposity types with circulating protein biomarkers…”
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Proteomic Analyses in Diverse Populations Improved Risk Prediction and Identified New Drug Targets for Type 2 Diabetes by Yao, Pang, Iona, Andri, Pozarickij, Alfred, Said, Saredo, Wright, Neil, Lin, Kuang, Millwood, Iona, Fry, Hannah, Kartsonaki, Christiana, Mazidi, Mohsen, Chen, Yiping, Bragg, Fiona, Liu, Bowen, Yang, Ling, Liu, Junxi, Avery, Daniel, Schmidt, Dan, Sun, Dianjianyi, Pei, Pei, Lv, Jun, Yu, Canqing, Hill, Michael, Bennett, Derrick, Walters, Robin, Li, Liming, Clarke, Robert, Du, Huaidong, Chen, Zhengming

“…Integrated analyses of plasma proteomics and genetic data in prospective studies can help assess the causal relevance of proteins, improve risk prediction, and…”
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Alcohol consumption and risks of more than 200 diseases in Chinese men by Im, Pek Kei, Wright, Neil, Yang, Ling, Chan, Ka Hung, Chen, Yiping, Guo, Yu, Du, Huaidong, Yang, Xiaoming, Avery, Daniel, Wang, Shaojie, Yu, Canqing, Lv, Jun, Clarke, Robert, Chen, Junshi, Collins, Rory, Walters, Robin G., Peto, Richard, Li, Liming, Chen, Zhengming, Millwood, Iona Y.

“…Alcohol consumption accounts for ~3 million annual deaths worldwide, but uncertainty persists about its relationships with many diseases. We investigated the…”
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Conventional and genetic associations of adiposity with 1463 proteins in relatively lean Chinese adults by Yao, Pang, Iona, Andri, Kartsonaki, Christiana, Said, Saredo, Wright, Neil, Lin, Kuang, Pozarickij, Alfred, Millwood, Iona, Fry, Hannah, Mazidi, Mohsen, Chen, Yiping, Du, Huaidong, Bennett, Derrick, Avery, Daniel, Schmidt, Dan, Pei, Pei, Lv, Jun, Yu, Canqing, Hill, Michael, Chen, Junshi, Peto, Richard, Walters, Robin, Collins, Rory, Li, Liming, Clarke, Robert, Chen, Zhengming

“…Adiposity is associated with multiple diseases and traits, but little is known about the causal relevance and mechanisms underlying these associations…”
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Long-Term Exposure to Fine Particulate Matter and Incidence of Esophageal Cancer: A Prospective Study of 0.5 Million Chinese Adults by Sun, Dong, Liu, Cong, Zhu, Yunqing, Guo, Yu, Yang, Ling, Chen, Yiping, Meng, Xia, Liu, Yang, Zhang, Jun, Schmidt, Dan, Chen, Zhengming, Lv, Jun, Li, Liming, Clarke, Robert, Collins, Rory, Guo, Yu, Li, Liming, Walters, Robin, Bennett, Derrick, Boxall, Ruth, Chan, Ka Hung, Chang, Yumei, Chen, Yiping, Clarke, Johnathan, Du, Huaidong, Hacker, Alex, Holmes, Michael, Im, Pek Kei, Iona, Andri, Morris, Sam, Nie, Qunhua, Ryder, Paul, Said, Saredo, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Yang, Ling, Yang, Xiaoming, Yao, Pang, Hou, Can, Pei, Pei, Liu, Chao, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Wang, Shaojie, Du, Ranran, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Lv, Silu, Yan, Shichun, Cui, Xiaoming, Wang, Chi, Wu, Zhenyuan, Luo, Huiming, Zheng, Xiangyang, Zhou, Yonglin, Su, Jian, Liu, Fang, Zhang, Jun, Zhang, Shuo, Liu, Jingchao, Lin, Mei, Lu, Zhenzhen, Zhou, Lifang, Xie, Changping, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Wang, Sisi, Zhang, Ningmei, Yuan, Mingqiang, Wu, Xia, Jiang, Wei, Sun, Qiang, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Feng, Shixian, Tian, Huizi, Sun, Huarong, He, Pan, Yu, Min, Hu, Ruying, Wang, Hao, Cao, Yuan, Jin, Donghui, Fu, Zhongxi, Zhang, Hao, Chen, Jianwei, Zhang, Libo, Qu, Chan

“…Evidence is sparse and inconclusive on the association between long-term fine (≤2.5 μm) particulate matter (PM2.5) exposure and esophageal cancer. We aimed to…”
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Plasma Proteomics to Identify Drug Targets for Ischemic Heart Disease by Mazidi, Mohsen, Wright, Neil, Yao, Pang, Kartsonaki, Christiana, Millwood, Iona Y, Fry, Hannah, Said, Saredo, Pozarickij, Alfred, Pei, Pei, Chen, Yiping, Avery, Daniel, Du, Huaidong, Schmidt, Dan Valle, Yang, Ling, Lv, Jun, Yu, Canqing, Chen, Junshi, Hill, Michael, Holmes, Michael V, Howson, Joanna M M, Peto, Richard, Collins, Rory, Bennett, Derrick A, Walters, Robin G, Li, Liming, Clarke, Robert, Chen, Zhengming

“…Integrated analyses of plasma proteomic and genetic markers in prospective studies can clarify the causal relevance of proteins and discover novel targets for…”
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Dairy consumption and risks of total and site-specific cancers in Chinese adults: an 11-year prospective study of 0.5 million people by Kakkoura, Maria G, Du, Huaidong, Guo, Yu, Yu, Canqing, Yang, Ling, Pei, Pei, Chen, Yiping, Sansome, Sam, Chan, Wing Ching, Yang, Xiaoming, Fan, Lei, Lv, Jun, Chen, Junshi, Li, Liming, Key, Timothy J, Chen, Zhengming

“…Previous studies of primarily Western populations have reported contrasting associations of dairy consumption with certain cancers, including a positive…”
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Tobacco smoking and risks of more than 470 diseases in China: a prospective cohort study by Xiao, Dan, Chen, Yiping, Du, Huaidong, Pei, Pei, Gilbert, Simon, Avery, Daniel, Kartsonaki, Christiana, Yu, Canqing, Chen, Junshi, Clarke, Robert, Avery, Daniel, Bennett, Derrick, Boxall, Ruth, Burgess, Sushila, Chan, Peter Ka Hung, Chen, Yiping, Chen, Zhengming, Clarke, Johnathan, Clarke, Robert, Du, Huaidong, Mohamed, Ahmed Edris, Hill, Mike, Im, Becky Pek Kei, Iona, Andri, Nie, Qunhua, Pozarickij, Alfred, Ryder, Paul, Said, Saredo, Walters, Robin, Wang, Lin, Yang, Ling, Guo, Yu, Han, Xiao, Hou, Can, Liu, Chao, Pei, Pei, Chen, Junshi, Peto, Richard, Chen, Naying, Liu, Duo, Tang, Zhenzhu, Jiang, Qilian, Li, Mingqiang, Liu, Yun, Meng, Fanwen, Meng, Jinhuai, Qin, Yulu, Wang, Sisi, Wei, Liuping, Zhou, Liyuan, Dong, Caixia, Wang, Tao, Zhang, Xi, Wang, Xiaohuan, Guo, Zhendong, Weng, Min, Wu, Shukuan, Guo, Ziyan, Xu, Qinai, Fan, Lei, Feng, Shixian, Zhang, Ding, Zhou, Gang, Gao, Yulian, He, Pan, Sun, Huarong, Zhang, Xukui, Chen, Biyun, Fu, Zhongxi, Xu, Qiaohua, Long, Huajun, Zhang, Hao, Tao, Ran, Yang, Jie, Zhou, Jinyi, Zhou, Yonglin, Jin, Jianrong, Liu, Fang, Liu, Jingchao, Lu, Yan, Ma, Liangcai, Gao, Ruqin, Li, Feifei, Liu, Yongmei, Ning, Feng, Pang, Zengchang, Tian, Xiaocao, Zhai, Yaoming, Zhang, Hua, Hou, Wei, Wang, Junzheng, Chen, Xiaofang, Wu, Xianping, Luo, Guojin, Gong, Weiwei, Hu, Ruying, Wang, Hao, Chen, Lingli, Wang, Chunmei, Zhang, Xiaoyi

“…Tobacco smoking is estimated to account for more than 1 million annual deaths in China, and the epidemic continues to increase in men. Large nationwide…”
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MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults by Bennett, Derrick A, Parish, Sarah, Millwood, Iona Y, Guo, Yu, Chen, Yiping, Turnbull, Iain, Yang, Ling, Lv, Jun, Yu, Canqing, Davey Smith, George, Wang, Yongjun, Wang, Yilong, Peto, Richard, Collins, Rory, Walters, Robin G, Li, Liming, Chen, Zhengming, Clarke, Robert

“…Abstract Background The relevance of folic acid for stroke prevention in low-folate populations such as in China is uncertain. Genetic studies of the…”
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Conventional and genetic associations of BMI with major vascular and non-vascular disease incidence and mortality in a relatively lean Chinese population: U-shaped relationship revisited by Iona, Andri, Bragg, Fiona, Fairhurst-Hunter, Zammy, Millwood, Iona Y, Wright, Neil, Lin, Kuang, Yang, Ling, Du, Huaidong, Chen, Yiping, Pei, Pei, Cheng, Liang, Schmidt, Dan, Avery, Daniel, Yu, Canqing, Lv, Jun, Clarke, Robert, Walters, Robin, Li, Liming, Parish, Sarah, Chen, Zhengming

“…Higher body mass index (BMI) is associated with higher incidence of cardiovascular and some non-cardiovascular diseases (CVDs/non-CVDs). However, uncertainty…”
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Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study by Zhu, Yunqing, Fan, Junning, Lv, Jun, Guo, Yu, Pei, Pei, Yang, Ling, Chen, Yiping, Du, Huaidong, Li, Feifei, Yang, Xiaoming, Avery, Daniel, Chen, Junshi, Chen, Zhengming, Yu, Canqing, Li, Liming

“…Little is known about the effects of maintaining healthy sleep patterns on frailty transitions. Based on 23,847 Chinese adults aged 30-79 in a prospective…”
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Predictive value of 8-year blood pressure measures in intracerebral haemorrhage risk over 5 years by Zhang, Yiqian, Ding, Yinqi, Yu, Canqing, Sun, Dianjianyi, Pei, Pei, Du, Huaidong, Yang, Ling, Chen, Yiping, Schmidt, Dan, Avery, Daniel, Chen, Jianwei, Chen, Junshi, Chen, Zhengming, Li, Liming, Lv, Jun

“…Abstract Aims The relationships between long-term blood pressure (BP) measures and intracerebral haemorrhage (ICH), as well as their predictive ability on ICH,…”
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PCSK9 genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations by Holmes, Michael V, Kartsonaki, Christiana, Boxall, Ruth, Lin, Kuang, Reeve, Nicola, Yu, Canqing, Lv, Jun, Bennett, Derrick A, Hill, Michael R, Yang, Ling, Chen, Yiping, Du, Huaidong, Turnbull, Iain, Collins, Rory, Clarke, Robert J, Tobin, Martin D, Li, Liming, Millwood, Iona Y, Chen, Zhengming, Walters, Robin G

“…Abstract Aims Lowering low-density lipoprotein cholesterol (LDL-C) through PCSK9 inhibition represents a new therapeutic approach to preventing and treating…”
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Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese by Yang, Songchun, Sun, Zhijia, Yu, Canqing, Guo, Yu, Pang, Yuanjie, Pei, Pei, Yang, Ling, Millwood, Iona Y, Chen, Yiping, Du, Huaidong, Lu, Yan, Clarke, Robert, Chen, Junshi, Clarke, Robert, Collins, Rory, Guo, Yu, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Burgess, Sue, Mohamed, Ahmed Edris, Fairhurst-Hunter, Zammy, Fry, Hannah, Gilbert, Simon, Hacker, Alex, Hill, Mike, Holmes, Michael, Kakkoura, Maria, Kartsonaki, Christiana, Kerosi, Rene, Mazidi, Mohsen, Millwood, Iona, Pozarickij, Alfred, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wright, Neil, Yang, Xiaoming, Yao, Pang, Han, Xiao, Pei, Pei, Liu, Chao, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Wang, Shaojie, Du, Ranran, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Lv, Silu, Yan, Shichun, Cui, Xiaoming, Wang, Chi, Wu, Zhenyuan, Luo, Huiming, Zheng, Xiangyang, Zhou, Yonglin, Su, Jian, Liu, Fang, Zhang, Jun, Zhang, Shuo, Liu, Jingchao, Lin, Mei, Lu, Zhenzhen, Zhou, Lifang, Xie, Changping, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Wang, Sisi, Zhang, Ningmei, Yuan, Mingqiang, Wu, Xia, Jiang, Wei, Sun, Qiang, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Feng, Shixian, Tian, Huizi, Sun, Huarong, Yu, Min, Hu, Ruying, Wang, Hao, Cao, Yuan, Jin, Donghui, Chen, Jianwei, Peng, Yuan

“…Background and purposePrevious studies, mostly focusing on the European population, have reported polygenic risk scores (PRSs) might achieve risk…”
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Association between health insurance cost-sharing and choice of hospital tier for cardiovascular diseases in China: a prospective cohort study by Clarke, Robert, Sun, Dianjianyi, Avery, Daniel, Zhang, Hua, Lv, Jun, Li, Liming, Yip, Winnie, Mihaylova, Borislava, Chen, Junshi, Clarke, Robert, Wang, Chen, Lv, Jun, Peto, Richard, Barnard, Maxim, Boxall, Ruth, Chan, Kahung, Chen, Yiping, Du, Huaidong, Mohamed, Ahmed Edris, Fry, Hannah, Gilbert, Simon, Im, Pek Kei, Kakkoura, Maria, Kartsonaki, Christiana, Lam, Hubert, Lin, Kuang, Liu, James, Millwood, Iona, Nie, Qunhua, Ryder, Paul, Said, Saredo, Stevens, Becky, Wang, Baihan, Wright, Neil, Yao, Pang, Han, Xiao, Hou, Can, Xia, Qingmei, Pei, Pei, Jiang, Qilian, Meng, Jinhuai, Qin, Yulu, Wang, Sisi, Ren, Xiaolan, Zhang, Hui, Wang, Xiaohuan, Guo, Zhendong, Li, Huimei, Weng, Min, Wu, Shukuan, Zou, Mingyuan, Zhou, Xue, Guo, Ziyan, Li, Yanjie, Xu, Qinai, Chang, Liang, Fan, Lei, Zhang, Ding, He, Tianyou, Sun, Huarong, Liu, Huilin, Xu, Qiaohua, Long, Huajun, Xu, Xin, Zhang, Libo, Su, Jian, Tao, Ran, Wu, Ming, Yang, Jie, Hu, Yihe, Jin, Jianrong, Liu, Jingchao, Ma, Liangcai, Tang, Aiyu, Zhang, Jun, Li, Feifei, Li, Shanpeng, Liu, Yongmei, Ning, Feng, Pang, Zengchang, Wang, Shaojie, Zhai, Yaoming, Luo, Guojin, Sun, Qiang, Gong, Weiwei, Hu, Ruying, Wang, Hao, Pan, Dongxia, Xie, Kaixu, Zhang, Xiaoyi, Wang, Xun, Zhang, Ning, Zhou, Shanshan, Ju, Naixin, Mao, Yiting, Li, Shuya, Du, Peng, Wang, Deren, Wang, Weizhi, Dong, Yi

“…Hospitals in China are classified into tiers (1, 2 or 3), with the largest (tier 3) having more equipment and specialist staff. Differential health insurance…”
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One-size-fits-all versus risk-category-based screening interval strategies for cardiovascular disease prevention in Chinese adults: a prospective cohort study by Sun, Zhijia, Sun, Dianjianyi, Pei, Pei, Yang, Ling, Zhang, Hao, Yang, Xiaoming, Barnard, Maxim, Li, Liming, Lv, Jun, Chen, Junshi, Li, Liming, Lv, Jun, Peto, Richard, Avery, Daniel, Bennett, Derrick, Chan, Ka Hung, Chen, Yiping, Clarke, Charlotte, Fry, Hannah, Gilbert, Simon, Im, Pek Kei, Iona, Andri, Kakkoura, Maria, Lam, Hubert, Mazidi, Mohsen, Millwood, Iona, Pozarickij, Alfred, Rahmati, Maryanm, Ryder, Paul, Said, Saredo, Stevens, Becky, Turnbull, Iain, Wang, Lin, Yang, Ling, Han, Xiao, Hou, Can, Xia, Qingmei, Liu, Chao, Gao, Ruqin, Li, Shanpeng, Duan, Haiping, Liu, Yongmei, Zang, Yajing, Cheng, Liang, Zhang, Hua, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Yan, Shichun, Cui, Xiaoming, Wu, Zhenyuan, Li, Yanjie, Kang, Quan, Luo, Huiming, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Yang, Jie, Fang Liu, Jian Su, Zhang, Jun, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Lin, Mei, Lu, Zhenzhen, Zhou, Lifang, Xie, Changping, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Wang, Sisi, Yuan, Mingqiang, Wu, Xia, Jiang, Wei, Sun, Qiang, Ren, Xiaolan, Dong, Caixia, Wang, Tao, Zhang, Xi, Kang, Kai, Feng, Shixian, Fan, Lei, Sun, Huarong, He, Pan, Zhang, Xukui, Hu, Ruying, Wang, Hao, Xie, Kaixu, Shen, Dun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Xin, Zhang, Hao, Qu, Chan

“…In non-high-risk individuals, risk-category-based atherosclerotic cardiovascular disease (ASCVD) screening strategies may be more cost-effective than…”
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