Search Results - "Sardone, Gian Luca"

Endothelial Cell Adhesion to the Extracellular Matrix Induces c-Src–Dependent VEGFR-3 Phosphorylation Without the Activation of the Receptor Intrinsic Kinase Activity by Galvagni, Federico, Pennacchini, Susanna, Salameh, Ahmad, Rocchigiani, Marina, Neri, Francesco, Orlandini, Maurizio, Petraglia, Felice, Gotta, Stefano, Sardone, Gian Luca, Matteucci, Giacomo, Terstappen, Georg C, Oliviero, Salvatore

“…RATIONALE:Integrins cooperate with growth factor receptors to promote downstream signaling for cell proliferation and migration. However, the mechanism of…”
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siRNA screen identifies QPCT as a druggable target for Huntington's disease by Jimenez-Sanchez, Maria, Lam, Wun, Hannus, Michael, Sönnichsen, Birte, Imarisio, Sara, Fleming, Angeleen, Tarditi, Alessia, Menzies, Fiona, Ed Dami, Teresa, Xu, Catherine, Gonzalez-Couto, Eduardo, Lazzeroni, Giulia, Heitz, Freddy, Diamanti, Daniela, Massai, Luisa, Satagopam, Venkata P, Marconi, Guido, Caramelli, Chiara, Nencini, Arianna, Andreini, Matteo, Sardone, Gian Luca, Caradonna, Nicola P, Porcari, Valentina, Scali, Carla, Schneider, Reinhard, Pollio, Giuseppe, O'Kane, Cahir J, Caricasole, Andrea, Rubinsztein, David C

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siRNA screen identifies QPCT as a druggable target for Huntington's disease by Jimenez-Sanchez, Maria, Lam, Wun, Hannus, Michael, Sönnichsen, Birte, Imarisio, Sara, Fleming, Angeleen, Tarditi, Alessia, Menzies, Fiona, Ed Dami, Teresa, Xu, Catherine, Gonzalez-Couto, Eduardo, Lazzeroni, Giulia, Heitz, Freddy, Diamanti, Daniela, Massai, Luisa, Satagopam, Venkata P, Marconi, Guido, Caramelli, Chiara, Nencini, Arianna, Andreini, Matteo, Sardone, Gian Luca, Caradonna, Nicola P, Porcari, Valentina, Scali, Carla, Schneider, Reinhard, Pollio, Giuseppe, O'Kane, Cahir J, Caricasole, Andrea, Rubinsztein, David C

“…An siRNA screen for genes that suppress mutant huntingtin toxicity in both mammalian cells and Drosophila identifies glutaminyl cyclase (QPCT). Newly generated…”
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Innovative Reversed-Phase Chromatography Platform Approach for the Fast and Accurate Characterization of Membrane Vesicles’ Protein Patterns by Nompari, Luca, Coccone, Salvatore Sanna, Sardone, Gian Luca, Corrado, Alessio, Berti, Stefania, Biagini, Massimiliano, Rovini, Michele, Magagnoli, Claudia, Cianetti, Simona, Orlandini, Serena, Furlanetto, Sandra, De Ricco, Riccardo

“…Outer membrane vesicles (OMVs) have been widely explored to develop vaccine candidates for bacterial pathogens due to their ability to combine adjuvant…”
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Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3‑d]pyrimidines for the Potential Treatment of Cystic Fibrosis by Pesci, Elisabetta, Bettinetti, Laura, Fanti, Paola, Galietta, Luis J. V, La Rosa, Salvatore, Magnoni, Letizia, Pedemonte, Nicoletta, Sardone, Gian Luca, Maccari, Laura

“…Cystic fibrosis (CF) is a lethal genetic disease caused by mutations of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) with a…”
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