Search Results - "Sardo, Luca"
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Subcutaneous infliximab CT-P13 without intravenous induction in psoriatic arthritis: A case report and pharmacokinetic considerations
Published in International journal of clinical pharmacology and therapeutics (01-03-2024)“…The biosimilar CT-P13, the first and only subcutaneous (SC) infliximab formulation, is recommended for patients with psoriatic arthritis (PsA) and can be…”
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Life of psi: How full-length HIV-1 RNAs become packaged genomes in the viral particles
Published in Virology (New York, N.Y.) (01-04-2014)“…Abstract As a member of the retrovirus family, HIV-1 packages its RNA genome into particles and replicates through a DNA intermediate that integrates into the…”
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Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant hormones, autophagy and plant immune system fine tuning during infection
Published in PloS one (28-02-2014)“…Tomato yellow leaf curl Sardinia virus (TYLCSV), a DNA virus belonging to the genus Begomovirus, causes severe losses in tomato crops. It infects only a…”
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Long-Term Outcomes and Discard Rate of Kidneys by Decade of Extended Criteria Donor Age
Published in Clinical journal of the American Society of Nephrology (07-02-2017)“…Extended criteria donors represent nowadays a main resource for kidney transplantation, and recovery criteria are becoming increasingly inclusive. However, the…”
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HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein
Published in Proceedings of the National Academy of Sciences - PNAS (12-01-2016)“…Retroviruses package a dimeric genome comprising two copies of the viral RNA. Each RNA contains all of the genetic information for viral replication. Packaging…”
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Insights Into Persistent HIV-1 Infection and Functional Cure: Novel Capabilities and Strategies
Published in Frontiers in microbiology (27-04-2022)“…Although HIV-1 replication can be efficiently suppressed to undetectable levels in peripheral blood by combination antiretroviral therapy (cART), lifelong…”
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Editorial: Novel Insights Into a Functional HIV Cure
Published in Frontiers in microbiology (01-12-2021)Get full text
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Real-time visualization of chromatin modification in isolated nuclei
Published in Journal of cell science (01-09-2017)“…Chromatin modification is traditionally assessed in biochemical assays that provide average measurements of static events given that the analysis requires…”
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Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein
Published in Proceedings of the National Academy of Sciences - PNAS (02-12-2014)“…Significance HIV-1 full-length RNA must go to specific subcellular compartments to carry out its functions as a template for translation of structural and…”
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Morphine exposure exacerbates HIV-1 Tat driven changes to neuroinflammatory factors in cultured astrocytes
Published in PloS one (25-03-2020)“…Despite antiretroviral therapy human immunodeficiency virus type-1 (HIV-1) infection results in neuroinflammation of the central nervous system that can cause…”
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Dynamics of HIV-1 RNA Near the Plasma Membrane during Virus Assembly
Published in Journal of virology (01-11-2015)“…To increase our understanding of the events that lead to HIV-1 genome packaging, we examined the dynamics of viral RNA and Gag-RNA interactions near the plasma…”
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FRET-Based Detection and Quantification of HIV-1 Virion Maturation
Published in Frontiers in microbiology (09-03-2021)“…HIV-1 infectivity is achieved through virion maturation. Virus particles undergo structural changes via cleavage of the Gag polyprotein mediated by the viral…”
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Exploring HIV-1 Maturation: A New Frontier in Antiviral Development
Published in Viruses (06-09-2024)“…HIV-1 virion maturation is an essential step in the viral replication cycle to produce infectious virus particles. Gag and Gag-Pol polyproteins are assembled…”
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Benzodiazepines Drive Alteration of Chromatin at the Integrated HIV-1 LTR
Published in Viruses (09-02-2020)“…Antiretroviral therapy (ART) lowers human immunodeficiency virus type 1 (HIV-1) viral load to undetectable levels, but does not eliminate the latent reservoir…”
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Single cell spatial profiling of FFPE splenic tissue from a humanized mouse model of HIV infection
Published in Biomarker research (08-10-2024)“…Latency remains a major obstacle to finding a cure for HIV despite the availability of antiretroviral therapy. Due to virus dormancy, limited biomarkers are…”
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Structural Determinants of the APOBEC3G N-Terminal Domain for HIV-1 RNA Association
Published in Frontiers in cellular and infection microbiology (21-05-2019)“…APOBEC3G (A3G) is a cellular protein that inhibits HIV-1 infection through virion incorporation. The interaction of the A3G N-terminal domain (NTD) with RNA is…”
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Allergic cheilitis due to stannous fluoride‐containing toothpaste: First case from Italy and mini‐review of previously published cases
Published in Contact dermatitis (01-10-2024)Get full text
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Relationship between clinical manifestations and serological profile in patients affected by Systemic Lupus Erythematosus
Published in Frontiers in immunology (2024)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by a variety of both signs and symptoms; it mainly affects women of…”
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Gag-Dependent Enrichment of HIV-1 RNA near the Uropod Membrane of Polarized T Cells
Published in Journal of Virology (01-11-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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New Onset of Giant Cell Arteritis following ChAdOx1-S (Vaxevria ® ) Vaccine Administration
Published in Vaccines (Basel) (01-02-2023)“…We report a 78-year-old man presenting with persistent headaches in vertex and temporo-parietal area; fatigue, worsening after walking; jaw claudication;…”
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